Søgeord (dengue) valgt.
53 emner vises.
1
Gut microbe blocks dengue and Zika viruses in mosquitoes
Catherine Offord
Science, 18.04.2024
Tilføjet 18.04.2024
2
Epidemiological investigation of dengue fever outbreak and its socioeconomic determinants in Banadir region, Somalia
BMC Infectious Diseases, 12.04.2024
Tilføjet 12.04.2024
Abstract Background Dengue has become an alarming global problem and is endemic in many countries, particularly in tropical and subtropical countries. The aim of this study was to investigate dengue fever outbreak in Banadir Region, Somalia, to understand the risk factors (time, place, personal characteristics). Methods A descriptive cross-sectional study was undertaken to determine the levels of circulating anti-dengue virus antibodies and DENV NS1 antigen among Banadir Region residents, while a questionnaire survey was conducted to understand the clinical and demographic characteristics of the patients. Results A total of 735 febrile patients were studied, with 55.6% men and 44.3% women. The majority of the participants were children aged 14 years and younger. Among them, 10.8% tested positive for IgM antibodies against dengue virus (DENV), while the prevalence of DENV NS1 antigen was 11.8%. Fever and myalgia were the most common symptoms observed in the DENV-positive patients. Conclusions A dengue fever outbreak has been confirmed in Banadir region, Somalia. This study provides information on the most affected districts and identifies risk factors contributing to DF outbreaks. The study recommends improving outbreak readiness and response, particularly in surveillance and laboratory diagnostics, by fostering intersectoral collaboration and establishing regulatory frameworks for financial and operational participation.
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3
Molecular identification and phylogenetic analysis of chikungunya virus among dengue-negative patients in Kolkata, India
Rajendra Prasad Chatterjee, Aroni Chatterjee, Sabbir Ansari, Shilpa Chatterjee, Shyamalendu Chatterjee, Nilanjan Chakraborty
PLoS One Infectious Diseases, 4.04.2024
Tilføjet 4.04.2024
by Rajendra Prasad Chatterjee, Aroni Chatterjee, Sabbir Ansari, Shilpa Chatterjee, Shyamalendu Chatterjee, Nilanjan Chakraborty Dengue and chikungunya are co-circulating vector-borne diseases that share a significant number of clinical symptoms. To identify variables to aid physicians in making rapid and effective diagnostic decisions, we performed molecular diagnosis of the chikungunya virus and examined the clinical manifestations of chikungunya cases to identify the prevalence among dengue-negative individuals in Kolkata. Dengue suspected patients’ samples were collected during January 2020—December 2021 and Enzyme-linked immunosorbent assay (ELISA) and reverse transcription-polymerase chain reaction (RT-PCR) methods have been performed to confirm the prevalence of chikungunya infection among dengue-negative patients. By performing phylogenetic analysis, comparing clinical classifications, identifying disease aetiology using clinical and laboratory factors, and evaluating the time course of several clinical variables, we have evaluated the clinical manifestations linked to dengue and chikungunya virus infections. Chikungunya infection was found in 15.1% and 6.3% of the 635 dengue-negative patients, as determined by ELISA and RT-PCR, respectively. Arthritis and myalgia were more common in chikungunya-infected patients at the time of hospital admission while conjunctivitis, photosensitivity, arthralgia, Anorexia, fatigue, retro-orbital pain, vomiting, dermatitis, or swollen glands were significantly presented as an overlapping symptom. Although dengue and chikungunya infections have significant clinical overlap, basic clinical and laboratory criteria can predict these diseases at presentation for proper management. Effective management enables doctors to treat and care for patients properly and contributes to the development of control measures for these infections in a medical setting.
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4
Historical Hot Spots of Dengue and Zika Viruses to Guide Targeted Vector Control in San Juan, Puerto Rico (2010–2022)
American Journal of Tropical Medicine and Hygiene, 3.04.2024
Tilføjet 3.04.2024
Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 110 Issue: 4 Pages: 731-737
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5
Low Rate of Asymptomatic Dengue Infection Detected in Coastal Kenya Using Pooled Polymerase Chain Reaction Testing
American Journal of Tropical Medicine and Hygiene, 3.04.2024
Tilføjet 3.04.2024
Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 110 Issue: 4 Pages: 738-740
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6
First-in-human trial evaluating safety and pharmacokinetics of AT-752, a novel nucleotide prodrug with pan-serotype activity against dengue virus
Xiao-Jian ZhouJason LickliterMaureen MontrondLaura IshakKeith PietropaoloDayle JamesBruce BelangerArantxa HorgaJanet Hammond1Atea Pharmaceuticals Inc, Boston, Massachusetts, USA2Nucleus Network, Melbourne, Australia, Miguel Angel Martinez
Antimicrobial Agents And Chemotherapy, 26.03.2024
Tilføjet 26.03.2024
7
[Articles] Effect of single-dose, live, attenuated dengue vaccine in children with or without previous dengue on risk of subsequent, virologically confirmed dengue in Cebu, the Philippines: a longitudinal, prospective, population-based cohort study
Michelle Ylade, Maria Vinna Crisostomo, Jedas Veronica Daag, Kristal An Agrupis, Anna Maureen Cuachin, Ava Kristy Sy, Deok Ryun Kim, Hyeon Seon Ahn, Ana Coello Escoto, Leah C Katzelnick, Cameron Adams, Laura White, Aravinda M de Silva, Jacqueline Deen, Anna Lena Lopez
Lancet Infectious Diseases, 23.03.2024
Tilføjet 23.03.2024
The risk of developing virologically confirmed dengue after a single dose of CYD-TDV varied by baseline DENV serostatus. Since the study assessed the effect of only a single dose, the findings cannot inform decisions on vaccination by public health officers. However, the findings have implications for children who receive an incomplete vaccination regimen and these results should prompt more detailed analyses in future trials on dengue vaccines.
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8
Improving dengue fever predictions in Taiwan based on feature selection and random forests
BMC Infectious Diseases, 20.03.2024
Tilføjet 20.03.2024
Abstract Background Dengue fever is a well-studied vector-borne disease in tropical and subtropical areas of the world. Several methods for predicting the occurrence of dengue fever in Taiwan have been proposed. However, to the best of our knowledge, no study has investigated the relationship between air quality indices (AQIs) and dengue fever in Taiwan. Results This study aimed to develop a dengue fever prediction model in which meteorological factors, a vector index, and AQIs were incorporated into different machine learning algorithms. A total of 805 meteorological records from 2013 to 2015 were collected from government open-source data after preprocessing. In addition to well-known dengue-related factors, we investigated the effects of novel variables, including particulate matter with an aerodynamic diameter
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9
Dengue encephalopathy in an adult due to dengue virus type 1 infection
BMC Infectious Diseases, 15.03.2024
Tilføjet 15.03.2024
Abstract Background Dengue is an important public health problem, which caused by the dengue virus (DENV), a single-stranded RNA virus consisted of four serotypes. Central nervus system (CNS) impairment in dengue usually results from DENV-2 or DENV-3 infection, which lead to life-threatening outcomes. Furthermore, neurological complications due to DENV-1 was rare especially in adult patients. Case presentation A 44-year-old man without comorbidities had lethargy after hyperpyrexia and a positive DENV NS1 antigen was detected for confirming the diagnosis of dengue on day 8 of onset. Then logagnosia, decreased muscle strength, delirium and irritability were occurred even radiographic examination were normal. He was treated with low-dose hormone, sedatives and gamma goblin with a short duration of 6 days. The cerebrospinal fluid (CSF) tests were persistent normal. However, presence of DENV-1 RNA was confirmed both in CSF and serum. Furthermore, the complete sequence of the DENV isolated from the patient’s serum was performed (GenBank No.: MW261838). The cytokines as IL-6, IL-10 and sVCAM-1 were increased in critical phase of disease. Finally, the patient was discharged on day 24 of onset without any neurological sequelae. Conclusion Encephalopathy caused by a direct CNS invasion due to DENV-1 during viremia was described in an adult patient. Treatment with low-dose hormone and gamma goblin was helpful for admission.
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10
Exploring community behaviours and stakeholder challenges in engaging communities with dengue prevention behaviour in Malaysia: implementation research for a qualitative study with a community-based participatory research design
Samsudin, N. A., Karim, N., Othman, H., Naserrudin, N. A., Sahani, M., Hod, R., Siau, C. S., Harif, M. N., Abd. Samad, B. H., Zaini, Z.-I. I.
BMJ Open, 13.03.2024
Tilføjet 13.03.2024
ObjectivesTo use a community-based participatory research (CBPR) design to explore local community behaviours and stakeholders’ challenges in engaging communities in dengue prevention behaviours in Hulu Langat, Selangor, Malaysia. DesignThis CBPR design in implementation comprised in-depth interviews (IDIs) and focus group discussions (FGDs). Themes were identified from the data with inductive and deductive thematic analysis. SettingFGDs were conducted in local community areas and IDIs were conducted in the local authority (LA) office and the Hulu Langat district health office. ParticipantsAll FGD and IDI participants consented to the study, and included health authorities (n=4), LAs (n=7), community leader (n=1), faith leader (n=1), patients diagnosed with dengue (IDIs, n=2) and permanent residents of Hulu Langat who had been exposed to dengue infectious disease (FGDs, n=27). ResultsThe main themes were categorised into community behaviour and stakeholder challenges. The community behaviour-related themes were awareness of dengue disease and Aedes mosquitoes, perception of risk and severity, and involvement of authorities. The themes related to stakeholder challenges were resource constraints and capacity issues, jurisdictional constraints and coordination, and educational dissemination and vandalism. ConclusionsThe actions of the authorities shape community and stakeholder behaviours. Effective communication, including clear and aesthetically pleasing messages, motivates individuals to take appropriate actions. It is crucial for the authorities to engage in inclusive communication and consider diverse perspectives, such as those of residents and individuals exposed to dengue infection. Authorities that provide accurate and unbiased information foster transparency and enable informed decision-making by all stakeholders.
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11
Forecasting weekly dengue incidence in Sri Lanka: Modified Autoregressive Integrated Moving Average modeling approach
Nilantha Karasinghe, Sarath Peiris, Ruwan Jayathilaka, Thanuja Dharmasena
PLoS One Infectious Diseases, 8.03.2024
Tilføjet 8.03.2024
by Nilantha Karasinghe, Sarath Peiris, Ruwan Jayathilaka, Thanuja Dharmasena Dengue poses a significant and multifaceted public health challenge in Sri Lanka, encompassing both preventive and curative aspects. Accurate dengue incidence forecasting is pivotal for effective surveillance and disease control. To address this, we developed an Autoregressive Integrated Moving Average (ARIMA) model tailored for predicting weekly dengue cases in the Colombo district. The modeling process drew on comprehensive weekly dengue fever data from the Weekly Epidemiological Reports (WER), spanning January 2015 to August 2020. Following rigorous model selection, the ARIMA (2,1,0) model, augmented with an autoregressive component (AR) of order 16, emerged as the best-fitted model. It underwent initial calibration and fine-tuning using data from January 2015 to August 2020, and was validated against independent 2000 data. Selection criteria included parameter significance, the Akaike Information Criterion (AIC), and Schwarz Bayesian Information Criterion (SBIC). Importantly, the residuals of the ARIMA model conformed to the assumptions of randomness, constant variance, and normality affirming its suitability. The forecasts closely matched observed dengue incidence, offering a valuable tool for public health decision-makers. However, an increased percentage error was noted in late 2020, likely attributed to factors including potential underreporting due to COVID-19-related disruptions amid rising dengue cases. This research contributes to the critical task of managing dengue outbreaks and underscores the dynamic challenges posed by external influences on disease surveillance.
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12
A dengue virus infection in Ethiopia: a systematic review and meta-analysis
BMC Infectious Diseases, 8.03.2024
Tilføjet 8.03.2024
Abstract Background Dengue is caused by a positive-stranded RNA virus called dengue virus, which is spread by Aedes mosquito species. It is a fast-growing acute febrile disease with potentially lethal consequences that is a global public health problem, mostly in tropical and subtropical countries. In Ethiopia, dengue fever is understudied, although the virus is still being transmitted and viral infection rates are rising. This systematic review and meta-analysis was aimed at estimating the pooled prevalence of DENV infection in Ethiopia. Methods A literature search was done on the PubMed, Hinari and Google Scholar databases to identify studies published before July, 2023. Random effects and fixed effects models were used to estimate the pooled prevalence of all three markers. The Inconsistency Index was used to assess the level of heterogeneity. Results A total of 11 studies conducted on suspected individuals with dengue fever and acutely febrile participants were included in this review. The majority of the studies had a moderate risk of bias and no study had a high risk of bias. A meta-analysis estimated a pooled IgG prevalence of 21% (95% CI: 19–23), a pooled IgM prevalence of 9% (95%CI: 4–13) and a pooled DENV-RNA prevalence of 48% (95% CI: 33–62). There is evidence of possible publication bias in IgG but not in the rest of the markers. Conclusion Dengue is prevalent among the dengue fever suspected and febrile population in Ethiopia. Healthcare providers, researchers and policymakers should give more attention to dengue fever.
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13
Brazil is hoping and waiting for a new vaccine as dengue rages
Marcia Triunfol
Science, 8.03.2024
Tilføjet 8.03.2024
14
A dengue virus infection in Ethiopia: a systematic review and meta-analysis
BMC Infectious Diseases, 7.03.2024
Tilføjet 7.03.2024
Abstract Background Dengue is caused by a positive-stranded RNA virus called dengue virus, which is spread by Aedes mosquito species. It is a fast-growing acute febrile disease with potentially lethal consequences that is a global public health problem, mostly in tropical and subtropical countries. In Ethiopia, dengue fever is understudied, although the virus is still being transmitted and viral infection rates are rising. This systematic review and meta-analysis was aimed at estimating the pooled prevalence of DENV infection in Ethiopia. Methods A literature search was done on the PubMed, Hinari and Google Scholar databases to identify studies published before July, 2023. Random effects and fixed effects models were used to estimate the pooled prevalence of all three markers. The Inconsistency Index was used to assess the level of heterogeneity. Results A total of 11 studies conducted on suspected individuals with dengue fever and acutely febrile participants were included in this review. The majority of the studies had a moderate risk of bias and no study had a high risk of bias. A meta-analysis estimated a pooled IgG prevalence of 21% (95% CI: 19–23), a pooled IgM prevalence of 9% (95%CI: 4–13) and a pooled DENV-RNA prevalence of 48% (95% CI: 33–62). There is evidence of possible publication bias in IgG but not in the rest of the markers. Conclusion Dengue is prevalent among the dengue fever suspected and febrile population in Ethiopia. Healthcare providers, researchers and policymakers should give more attention to dengue fever.
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15
Preferences and Demand for Mosquito Control among Dengue-Endemic Communities in Peñuelas, Puerto Rico: An Application of the Best-Worst Choice Model
American Journal of Tropical Medicine and Hygiene, 6.03.2024
Tilføjet 6.03.2024
Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 110 Issue: 3 Pages: 540-548
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16
Use of Household Insecticides against Mosquitoes in Dengue-Endemic Areas in Sri Lanka
American Journal of Tropical Medicine and Hygiene, 6.03.2024
Tilføjet 6.03.2024
Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 110 Issue: 3 Pages: 549-556
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17
Arbovirus impact on mosquito behavior: the jury is still out
Théo Maire, Louis Lambrechts, Felix J.H. Hol
Trends in Parasitology, 29.02.2024
Tilføjet 29.02.2024
Parasites can manipulate host behavior to enhance transmission, but our understanding of arbovirus-induced changes in mosquito behavior is limited. Here, we explore current knowledge on such behavioral alterations in mosquito vectors, focusing on host-seeking and blood-feeding behaviors. Reviewing studies on dengue, Zika, La Crosse, Sindbis, and West Nile viruses in Aedes or Culex mosquitoes reveals subtle yet potentially significant effects. However, assay heterogeneity and limited sample sizes challenge definitive conclusions. To enhance robustness, we propose using deep-learning tools for automated behavior quantification and stress the need for standardized assays. Additionally, conducting longitudinal studies across the extrinsic incubation period and integrating diverse traits into modeling frameworks are crucial for understanding the nuanced implications of arbovirus-induced behavioral changes for virus transmission dynamics.
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18
[Articles] An observer-blind, randomised, placebo-controlled, phase 1, single ascending dose study of dengue monoclonal antibody in healthy adults in Australia
Bhagwat Gunale, Nicholas Farinola, Chandrashekhar D Kamat, Cyrus S Poonawalla, Sambhaji S Pisal, Rajeev M Dhere, Claire Miller, Prasad S Kulkarni
Lancet Infectious Diseases, 24.02.2024
Tilføjet 24.02.2024
Dengue monoclonal antibody was safe and well tolerated. It showed a dose-proportionate increase in pharmacokinetic exposure. These data support further evaluation of dengue monoclonal antibody in patients with dengue for safety and efficacy.
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19
Dominant epitopes of cross‐reactive anti‐domain III human antibody response change from early to late convalescence of infection with dengue virus
Luis Gabriel González‐Lodeiro, Alejandro Martín Dunn, Dayron Martín Prieto, Danya Medina‐Carrasco, Lisandra E. García de Castro, Daniela Maldonado Bauzá, Glay Chinea Santiago, Vivian Huerta Galindo
Journal of Medical Virology, 20.02.2024
Tilføjet 20.02.2024
20
Initiatives and Challenges of Dengue Incidence in the Philippines
Journal of Infectious Diseases, 20.02.2024
Tilføjet 20.02.2024
21
Integration of population-level data sources into an individual-level clinical prediction model for dengue virus test positivity
Robert J. Williams, Ben J. Brintz, Gabriel Ribeiro Dos Santos, Angkana T. Huang, Darunee Buddhari, Surachai Kaewhiran, Sopon Iamsirithaworn, Alan L. Rothman, Stephen Thomas, Aaron Farmer, Stefan Fernandez, Derek A. T. Cummings, Kathryn B. Anderson, Henrik Salje, Daniel T. Leung
Science Advances, 17.02.2024
Tilføjet 17.02.2024
22
[Seminar] Dengue
Gabriela Paz-Bailey, Laura E Adams, Jacqueline Deen, Kathryn B Anderson, Leah C Katzelnick
Lancet, 16.02.2024
Tilføjet 16.02.2024
Dengue, caused by four closely related viruses, is a growing global public health concern, with outbreaks capable of overwhelming health-care systems and disrupting economies. Dengue is endemic in more than 100 countries across tropical and subtropical regions worldwide, and the expanding range of the mosquito vector, affected in part by climate change, increases risk in new areas such as Spain, Portugal, and the southern USA, while emerging evidence points to silent epidemics in Africa. Substantial advances in our understanding of the virus, immune responses, and disease progression have been made within the past decade.
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23
Within-host models unravelling the dynamics of dengue reinfections
Infectious Disease Modelling, 7.02.2024
Tilføjet 7.02.2024
Publication date: Available online 7 February 2024 Source: Infectious Disease Modelling Author(s): Vizda Anam, Bruno V. Guerrero, Akhil Kumar Srivastav, Nico Stollenwerk, Maíra Aguiar
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24
Chronic and neurotropic: A paradigm-challenging case of dengue virus encephalitis in patient with advanced human immunodeficiency virus infection
Clinical Infectious Diseases, 7.02.2024
Tilføjet 7.02.2024
Abstract A 32-year-old female with advanced HIV infection presented to an Australian hospital with subacute but worsening symptoms of encephalitis. Metagenomic sequencing and Dengue NS3 antigen staining of brain tissue confirmed active Dengue virus (DENV) encephalitis. The most recent possible DENV exposure was months prior in West Africa, indicating chronicity.
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25
Severe disease during both primary and secondary dengue virus infections in pediatric populations
Charu Aggarwal, Hasan Ahmed, Pragati Sharma, Elluri Seetharami Reddy, Kaustuv Nayak, Mohit Singla, Deepti Maheshwari, Yadya M. Chawla, Harekrushna Panda, Ramesh Chandra Rai, Sivaram Gunisetty, Lalita Priyamvada, Siddhartha Kumar Bhaumik, Syed Fazil Ahamed, Rosario Vivek, Priya Bhatnagar, Prabhat Singh, Manpreet Kaur, Kritika Dixit, Sanjeev Kumar, Kamal Gottimukkala, Keshav Saini, Prashant Bajpai, Gopinathan Pillai Sreekanth, Shobha Mammen, Anand Rajan, Valsan Philip Verghese, Asha Mary Abraham, Paresh Shah, Kalichamy Alagarasu, Tianwei Yu, Carl W. Davis, Jens Wrammert, Aftab Ansari, Rustom Antia, Sushil Kumar Kabra, Guruprasad R. Medigeshi, Rafi Ahmed, Rakesh Lodha, Anita Shet, Anmol Chandele, Kaja Murali-Krishna
Nature, 6.02.2024
Tilføjet 6.02.2024
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Assessing the basic knowledge and awareness of dengue fever prevention among migrant workers in Klang Valley, Malaysia
Maryam N. Chaudhary, Voon-Ching Lim, Erwin Martinez Faller, Pramod Regmi, Nirmal Aryal, Siti Nursheena Mohd Zain, Adzzie Shazleen Azman, Norhidayu Sahimin
PLoS One Infectious Diseases, 1.02.2024
Tilføjet 1.02.2024
by Maryam N. Chaudhary, Voon-Ching Lim, Erwin Martinez Faller, Pramod Regmi, Nirmal Aryal, Siti Nursheena Mohd Zain, Adzzie Shazleen Azman, Norhidayu Sahimin Background Globally, 390 million dengue virus infections occur per year. In Malaysia, migrant workers are particularly vulnerable to dengue fever (DF) due to mosquito breeding sites exposure and poor health literacy. Therefore, this study aimed to (i) assess the current DF knowledge, attitudes and practices (KAP), and (ii) identify strategies to promote DF awareness, among migrant workers in Klang Valley. Method A survey was conducted with 403 Nepali, Filipino and Indonesian migrant workers through phone interviews and online self-administered questionnaires. Piecewise structural equation modelling was applied to identify predictor variables for DF KAP. Results Most respondents were male, working in the services industry, had completed high school, aged between 30–39 years and with less than ten years work experience in Malaysia. Overall, respondents’ knowledge was positively correlated with attitude but negatively with practices. Older respondents, who had completed higher education, obtained higher knowledge scores. Similarly, those with working experience of >20 years in Malaysia obtained higher attitude scores. Respondents with a previous history of DF strongly considered the removal of mosquito breeding sites as their own responsibility, hence tended to frequently practise DF preventive measures. Respondents’ knowledge was also positively correlated to their understanding of DF information sourced from social media platforms. Conclusion These findings highlighted: (i) the need for targeted DF educational intervention among younger and newly arrived workers with lower levels of education and (ii) maximising the usage of social media platforms to improve DF public awareness.
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27
Live, Attenuated, Tetravalent Butantan–Dengue Vaccine in Children and Adults
Esper G. Kallás, Monica A.T. Cintra, José A. Moreira, Elizabeth G. Patiño, Patricia Emilia Braga, Juliana C.V. Tenório, Vanessa Infante, Ricardo Palacios, Marcus Vínicius Guimarães de Lacerda, Dhelio Batista Pereira, Allex Jardim da Fonseca, Ricardo Queiroz Gurgel, Ivo Castelo-Branco Coelho, Cor Jesus Fernandes Fontes, Ernesto T.A. Marques, Gustavo Adolfo Sierra Romero, Mauro Martins Teixeira, André M. Siqueira, Aldina Maria Prado Barral, Viviane Sampaio Boaventura, Fabiano Ramos, Erivaldo Elias Júnior, José Cassio de Moraes, Dimas T. Covas, Jorge Kalil, Alexander Roberto Precioso, Stephen S. Whitehead, Alejandra Esteves-Jaramillo, Tulin Shekar, Jung-Jin Lee, Julieta Macey, Sabrina Gozlan Kelner, Beth-Ann G. Coller, Fernanda Castro Boulos, Mauricio L. Nogueira
New England Journal of Medicine, 1.02.2024
Tilføjet 1.02.2024
28
Three Dengue Vaccines — What Now?
Scott B. Halstead
New England Journal of Medicine, 1.02.2024
Tilføjet 1.02.2024
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Whole genome sequencing unravels cryptic circulation of divergent dengue virus lineages in the rainforest region of Nigeria
Bernard Anyebe OnojaJudith Uche OguzieUwem Etop GeorgeKaego Emmanuel AsohPhilip AjayiToluwanimi Faithful OmofayeImafidon Oluwatoyin IgelekePhilomena EromonSoumare HarounaEdyth ParkerAdekunle Johnson AdenijiChristian T. Happia Department of Virology, College of Medicine, University of Ibadan, Ibadan, Oyo State, Nigeriab Department of Biological Sciences, Faculty of Natural Sciences, Redeemer’s University, Ede, Osun State, Nigeriac African Center of Excellence for Genomics of Infectious Diseases, Redeemer’s University, Ede, Osun State, Nigeriad Department of Medical Laboratory Science, College of Medicine, University of Ibadan, Ibadan, State Nigeriae Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA, USAf Department of Immunology and Infectious Diseases, Harvard T H Chan School of Public Health, Boston, MA, USA
Emerg Microbes Infect, 31.01.2024
Tilføjet 31.01.2024
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Risk factors associated with severe dengue in Latin America: A systematic review and meta‐analysis
Victoria Cruz Paraná, Caroline Alves Feitosa, Greice Carolina Santos da Silva, Luana Leandro Gois, Luciane Amorim Santos
Tropical Medicine & International Health, 24.01.2024
Tilføjet 24.01.2024
31
Detection of anti-premembrane antibody as a specific marker of four flavivirus serocomplexes and its application to serosurveillance in endemic regions
Guan-Hua ChenYu-Ching DaiSzu-Chia HsiehJih-Jin TsaiAva Kristy SyMario JizCelia PedrosoCarlos BritesEduardo Martins NettoPhyllis J. KankiDanielle R. D. SaundersDana L. VanlandinghamStephen HiggsYan-Jang S. HuangWei-Kung Wanga Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, HI, USAb Tropical Medicine Center, Kaohsiung Medical University Hospital, Kaohsiung, Taiwanc Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwand School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwane National Reference Laboratory for Dengue and Other Arbovirus, Virology Department, Research Institute for Tropical Medicine, Muntinlupa City, Philippinesf Immunology Department, Research Institute for Tropical Medicine, Muntinlupa City, Philippinesg LAPI-Laboratório de Pesquisa em Infectologia-School of Medicine, Federal University of Bahia, Salvador, Brazilh Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA, USAi Department of Biology, United States Air Force Academy, Colorado Springs, CO, USAj Biosecurity Research Institute and Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, USA
Emerg Microbes Infect, 23.01.2024
Tilføjet 23.01.2024
32
The burden of dengue in children and risk factors of transmission in nine districts in Sri Lanka
Chandima Jeewandara, Maneshka Vindesh Karunananda, Suranga Fernando, Saubhagya Danasekara, Gamini Jayakody, Segarajasingam Arulkumaran, Nayana Yasindu Samaraweera, Sarathchandra Kumarawansha, Subramaniyam Sivaganesh, Priyadarshanie Geethika Amarasinghe, Chintha Jayasinghe, Dilini Wijesekara, Manonath Bandara Marasinghe, Udari Mambulage, Helanka Wijayatilake, Kasun Senevirathne, Aththidayage Don Priyantha Bandara, Chandana Pushpalal Gallage, Nilu Ranmali Colambage, Ampe Arachchige Thilak Udayasiri, Tharaka Lokumarambage, Yasanayakalage Upasena, Wickramasinghe Pathiranalage Kasun Paramee Weerasooriya, Seroprevalence Study Group, Lahiru Perera, Pradeep Pushpakumara, Laksiri Gomes, Jeewantha Jayamali, Inoka Sepali Aberathna, Thashmi Nimasha, Madushika Dissanayake, Shyrar Ramu, Deneshan Peranantharajah, Hashini Colambage, Rivindu Wickramanayake, Harshani Chathurangika, Farha Bary, Sathsara Yatiwelle, Michael Harvie, Maheli Deheragoda, Tibutius Jayadas, Shashini Ishara, Dinuka Ariyaratne, Shashika Dayarathna, Ruwanthi Wijekulasuriya, Chathura Ranathunga, Graham S. Ogg, Gathsaurie N. Malavige
Journal of Medical Virology, 19.01.2024
Tilføjet 19.01.2024
33
[World Report] Brazil to start widespread dengue vaccinations
Lise Alves
Lancet, 12.01.2024
Tilføjet 12.01.2024
Millions will be eligible as Brazil becomes the first country to include Qdenga in its public health system. Lise Alves reports from São Paulo.
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34
The mosquito core virome: beyond the buzz
Lander De Coninck, Jelle Matthijnssens
Trends in Parasitology, 7.01.2024
Tilføjet 7.01.2024
Mosquito-specific viruses (MSVs), and mosquito viromes in general, have been a hot topic in research for the past few years. The general belief is that MSVs could have an influence on the vector competence of mosquitoes and thereby reduce the burden of disease of arboviruses. This idea is strengthened by studies that have shown an influence of MSVs on arbovirus infection in mosquitoes [1–3], and additionally by the recent success of release programs involving Aedes aegypti infected with the endobacterium Wolbachia, which result in a reduction of dengue cases up to 97% [4,5].
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35
Dengue in Cebu City, Philippines: A Pilot Study of Predictive Models and Visualizations for Public Health
American Journal of Tropical Medicine and Hygiene, 3.01.2024
Tilføjet 3.01.2024
Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 110 Issue: 1 Pages: 179-187
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36
Dengue in Cebu City, Philippines: A Pilot Study of Predictive Models and Visualizations for Public Health
American Journal of Tropical Medicine and Hygiene, 3.01.2024
Tilføjet 3.01.2024
Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 110 Issue: 1 Pages: 179-187
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37
Expanding the roles of community health workers to sustain programmes during malaria elimination: a meeting report on operational research in Southeast Asia
Malaria Journal, 2.01.2024
Tilføjet 2.01.2024
Abstract In Southeast Asia malaria elimination is targeted by 2030. Cambodia aims to achieve this by 2025, driven in large part by the urgent need to control the spread of artemisinin-resistant falciparum malaria infections. Rapid elimination depends on sustaining early access to diagnosis and effective treatment. In much of Cambodia, rapid elimination will rely on a village malaria worker (VMW) network. Yet as malaria declines and is no longer a common cause of febrile illness, VMWs may become less popular with febrile patients, as VMWs do not diagnose or treat other conditions at present. There is a risk that VMWs become inactive and malaria rebounds before the complete interruption of transmission is achieved. During 2021–23 a large-scale operational research study was conducted in western Cambodia to explore how a VMW network could be sustained by including health activities that cover non-malarial illnesses to encourage febrile patients to continue to attend. 105 VMWs received new rapid diagnostic tests (including dengue antigen–antibody and combined malaria/C-reactive protein tests), were trained in electronic data collection, and attended health education packages on hygiene and sanitation, disease surveillance and first aid, management of mild illness, and vaccination and antenatal care. In August 2023 the National Malaria Control Programme of Cambodia convened a stakeholder meeting in Battambang, Cambodia. Findings from the study were reviewed in the context of current malaria elimination strategies. The discussions informed policy options to sustain the relevance of the VMW network in Cambodia, and the potential for its integration with other health worker networks. This expansion could ensure VMWs remain active and relevant until malaria elimination is accomplished.
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38
Wastewater-based surveillance of vector-borne pathogens: a cautionary note
Farah Ishtiaq
Trends in Parasitology, 30.12.2023
Tilføjet 30.12.2023
Diamond et al. recently identified malaria and dengue as high-priority diseases in wastewater surveillance for climate-change-driven shifts in pathogen dynamics. When employing wastewater surveillance for vector-borne pathogens it is essential to take into account the geographical context, pathogen biology, and the availability of sewage networks for meaningful interventions.
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39
Spatial analysis of Dengue through the reproduction numbers relating to socioeconomic features: Case studies on two Brazilian urban centers
Infectious Disease Modelling, 23.12.2023
Tilføjet 23.12.2023
Publication date: Available online 22 December 2023 Source: Infectious Disease Modelling Author(s): Ana T.C. Silva, Rejane C. Dorn, Lívia R. Tomás, Leonardo B.L. Santos, Lacita M. Skalinski, Suani T.R. Pinho
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40
Downscaling epidemiological time series data for improving forecasting accuracy: An algorithmic approach
Mahadee Al Mobin, Md. Kamrujjaman
PLoS One Infectious Diseases, 15.12.2023
Tilføjet 15.12.2023
by Mahadee Al Mobin, Md. Kamrujjaman Data scarcity and discontinuity are common occurrences in the healthcare and epidemiological dataset and often is needed to form an educative decision and forecast the upcoming scenario. Often to avoid these problems, these data are processed as monthly/yearly aggregate where the prevalent forecasting tools like Autoregressive Integrated Moving Average (ARIMA), Seasonal Autoregressive Integrated Moving Average (SARIMA), and TBATS often fail to provide satisfactory results. Artificial data synthesis methods have been proven to be a powerful tool for tackling these challenges. The paper aims to propose a novel algorithm named Stochastic Bayesian Downscaling (SBD) algorithm based on the Bayesian approach that can regenerate downscaled time series of varying time lengths from aggregated data, preserving most of the statistical characteristics and the aggregated sum of the original data. The paper presents two epidemiological time series case studies of Bangladesh (Dengue, Covid-19) to showcase the workflow of the algorithm. The case studies illustrate that the synthesized data agrees with the original data regarding its statistical properties, trend, seasonality, and residuals. In the case of forecasting performance, using the last 12 years data of Dengue infection data in Bangladesh, we were able to decrease error terms up to 72.76% using synthetic data over actual aggregated data.
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41
Climate change and the rising incidence of vector-borne diseases globally
Angella M. George, Rashid Ansumana, Dziedzom K. de Souza, Vettakkara Kandy Muhammed Niyas, Alimuddin Zumla, Moses J Bockarie
International Journal of Infectious Diseases, 13.12.2023
Tilføjet 13.12.2023
As the world experiences warmer weather, heat waves and flooding, the climate change is leading to the geographical expansion of mosquitos, which are known vectors of a range of infectious diseases like dengue, malaria, chikungunya, yellow fever, rift valley fever, West Nile fever, Japanese encephalitis and Zika which affect millions of people worldwide (1). Climate change now threatens the spread of vector-borne diseases to previously low-risk areas in Africa, Asia, Europe, and the Americas (2-7) According to the World Health Organization (WHO), an additional 250,000 deaths per year will occur in the next decades as a result of malnutrition, heat stress and vector-borne diseases (8).
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42
Severity of Dengue Viral Infection Based on Clinical and Hematological Parameters among Pakistani Patients
American Journal of Tropical Medicine and Hygiene, 7.12.2023
Tilføjet 7.12.2023
Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 109 Issue: 6 Pages: 1284-1289
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43
Did COVID-19 or COVID-19 Vaccines Influence the Patterns of Dengue in 2021? An Exploratory Analysis of Two Observational Studies from North India
American Journal of Tropical Medicine and Hygiene, 7.12.2023
Tilføjet 7.12.2023
Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 109 Issue: 6 Pages: 1290-1297
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44
Characterization of Dengue Virus Serotype 2 Cosmopolitan Genotype Circulating in Colombia
American Journal of Tropical Medicine and Hygiene, 7.12.2023
Tilføjet 7.12.2023
Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 109 Issue: 6 Pages: 1298-1302
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45
Effect of previous heterologous flavivirus vaccinations on human antibody responses in tick‐borne encephalitis and dengue virus infections
Lena Roßbacher, Stefan Malafa, Kristina Huber, Melissa Thaler, Stephan W. Aberle, Judith H. Aberle, Franz X. Heinz, Karin Stiasny
Journal of Medical Virology, 28.11.2023
Tilføjet 28.11.2023
46
An outbreak of a novel lineage of dengue virus 2 in Vietnam in 2022
Takeshi Nabeshima, Mya Myat Ngwe Tun, Nguyen Thi Thu Thuy, Nguyen Le Khanh Hang, Le Thi Quynh Mai, Futoshi Hasebe, Yuki Takamatsu, Nagasaki University Vietnam Research Group
Journal of Medical Virology, 28.11.2023
Tilføjet 28.11.2023
47
Role of pre-existing immunity in driving the dengue virus serotype 2 genotype shift in the Philippines: A retrospective analysis of serological data
Jean Claude Balingit, Mark Pierre S. Dimamay, Ryosuke Suzuki, Mami Matsuda, Dalouny Xayavong, Mya Myat Ngwe Tun, Ronald R. Matias, Filipinas F. Natividad, Meng Ling Moi, Yuki Takamatsu, Richard Culleton, Corazon C. Buerano, Kouichi Morita
International Journal of Infectious Diseases, 28.11.2023
Tilføjet 28.11.2023
The dengue virus (DENV) consists of four distinct serotypes (DENV1-4) [1], with each serotype further classified into genetically distinct genotypes. Following primary infection with DENV, serotype-specific and cross-serotype antibodies provide protection from re-infection. However, only serotype-specific neutralizing antibodies are thought to provide complete protection against re-infection with the same serotype. Cross-serotype antibodies with neutralizing activity against the remaining serotypes wane over time [2,3], and may eventually enhance secondary infection with a different serotype [4].
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48
Alarming trends in dengue incidence and mortality in Bangladesh
Journal of Infectious Diseases, 25.11.2023
Tilføjet 25.11.2023
AbstractBangladesh is currently experiencing the country’s largest and deadliest dengue outbreak on record. This year’s outbreak has been characterized by an early seasonal surge in cases, rapid geographic spread, and a high fatality rate. The alarming trends in dengue incidence and mortality this year is an urgent wake-up call for public health policymakers and researchers to pay closer attention to dengue dynamics in South Asia, to strengthen the surveillance system and diagnostic capabilities, and to develop tools and methods for guiding strategic resource allocation and control efforts.
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49
Advances and challenges in synthetic biology for mosquito control
Shih-Che Weng, Reem A. Masri, Omar S. Akbari
Trends in Parasitology, 24.11.2023
Tilføjet 24.11.2023
Mosquito-borne illnesses represent a significant global health peril, resulting in approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are continuously expanding their global reach, driven by factors that escalate mosquito populations and pathogen transmission. Innovative control measures are imperative to combat these catastrophic ailments. Conventional approaches, such as eliminating breeding sites and using insecticides, have been helpful, but they face challenges such as insecticide resistance and environmental harm. Given the mounting severity of mosquito-borne diseases, there is promise in exploring innovative approaches using synthetic biology to bolster mosquitoes\' resistance to pathogens, or even eliminate the mosquito vectors, as a means of control. This review outlines current strategies, future goals, and the importance of gene editing for global health defenses against mosquito-borne diseases.
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50
Lambda-free light chain: A serum marker of dengue disease via NS3 protease-mediated antibody cleavage
Sheng-Hsuan WangBai-Jiun KuoTzu-Chuan HoShu-Wen WanKo-Lun YenPo-Hui HuangOscar Guey Chuen PerngPo-Lin ChenYu-Wen ChienYu-Chih Loa Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwanb Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwanc Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwand Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan, Taiwane Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwanf Center for Infection Control, National Cheng Kung University Medical College and Hospital, Tainan, Taiwang Department of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwanh Department of Occupational and Environmental Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
Virulence, 21.11.2023
Tilføjet 21.11.2023