Manfredi Gagliano, Costanza Marchiani, Giulia Bandini, Paolo Bernardi, Nicolas Palagano, Elisa Cioni, Martina Finocchi, Silvia Bellando Randone, Alberto Moggi Pignone

Spondylodiscitis are infections whose incidence has been rising through an increase in the susceptible population and improved diagnostic skills. Fungal spondylodiscitis is uncommon (0.5%–1.6%) and usually due to Candida albicans (Gouliouris et al., 2010; Berbari et al., 2015). Candida glabrata, formerly known as Torulopsis glabrata, is a common saprophyte in the gastrointestinal, genitourinary, and respiratory tracts and an opportunistic pathogen of low virulence (Berkowitz et al., 1979). Infections caused by C.

Jeroen G.V. Habets J, Onno P.M. Teernstra, Wouter L.W. van Hemert, Catharina K. Linssen, Roel J.J. Heijboer, Kim Rijkers

Abstract Introduction Many clinical manifestations can be related to Tropheryma whipplei infection. Case report We report a Tropheryma whipplei limbic encephalitis developed as a relapse of classical Whipple’s disease. Discussion This case is to the best of our knowledge the first proof of the effective brain–blood barrier crossing of both doxycycline and hydroxychloroquine as demonstrated by direct concentration monitoring on brain biopsy.

Safia Nadji, Marie-Charlotte Chopin, Camille Bourdon, R. Desbarbieux, Jean-Marie Marissael, Sylvie Armand, Frédéric Wallet, Caroline Loiez

Abstract Introduction Aerococccus urinae (AU) is a pathogen mainly identified in male urinary tract infections and responsible for bacteremia and endocarditis. To the best of our knowledge, there are only five patients with osteomyelitis due to AU described in the literature. All of them had urinary tract disease or systemic conditions such as diabetes, and two were associated with an endocarditis. Case report We described the first case of isolated spondylodiscitis without general or local predisposing condition, excepted age > 65 years.