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Dokumenter (1)

Senest revideret i maj 2016. Arbejdsgruppen bestod af: Jan Gerstoft, Alex Laursen, Suzanne Lunding, Peer Brehm Christensen, Christian Erikstrup, Terese Katzenstein, Alex Laursen, Birgitte Mørn og Nina Weis.


Sider (1)

…re research:Margolis et al: Latency reversal and viral clearance to cure HIV-1. Science. 2016; 253: aaf6517 PREP og PEP:Fonner et al. Effectiveness and safety of oral HIV preexposure prophylaxis for all populations: AIDS 2016 Jul 31;30(1…


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Nyt fra tidsskrifterne (10)

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13.07.2017
Figure 1.

10.07.2017
…chanisms of their activation and regulation remain unknown. The expression of epithelium and neutrophil-derived host defense peptides (HDPs; LL-37, human β-defensin-3), which activate mast cells via Mas-related G protein coupled receptor X2 (MRG…

19.06.2017
…elated to that link have not been fully elucidated. Porphyromonas gingivalis, a major pathogen of periodontitis, expresses dipeptidyl peptidase 4 (DPP4), which is involved in regulation of blood glucose levels by cleaving incretins in humans. We exam…

31.05.2017
Glucagon-like peptide 1 (GLP-1) regulates glucose homeostasis through the control of insulin release from the pancreas. GLP-1 peptide agonists are efficacious drugs for the treatment of diabetes. To gain insight into the molecular mechanism of action…

10.04.2017
…mong the mutants, one was noteworthy for its particularly low virulence gene expression level and mapped to an x-prolyl aminopeptidase (PepP). We show that this peptidase plays a role in posttranslational activation of the major virulence regulator, …

27.03.2017
…one of the two incomplete oppABCDF operons and a further three had insertions in distinct hypothetical genes, two containing peptidase motifs and one a member of a gene family. The three hypothetical gene mutants and the two with insertions in oppD1 …

13.02.2017
…ing mechanisms, could provide novel prevention and treatment options for pneumococcal diseases. Streptococcus pneumoniae endopeptidase O (PepO) is a newly discovered and ubiquitously expressed pneumococcal virulence protein. A PepO-mutant strain show…

10.02.2017
The quest to discover novel antigenic targets for the differential diagnosis of active and latent tuberculosis (TB) presents a challenging task. Although efforts are manifold and performed on a global scale, biological markers derived from Mycobacter…

7.02.2017
…sociated with increased resistance to host immune defences and antimicrobial agents. Here, we demonstrate that antimicrobial peptides (AMPs) are an effective anti-biofilm treatment when applied as catheter lock solutions (CLSs) in the treatment of &l…

9.01.2017
Embedded in the colonic mucus are cathelicidins, small cationic peptides secreted by colonic epithelial cells. Humans and mice have one cathelicidin-related antimicrobial peptide (CRAMP), LL-37/hCAP-18 and Cramp respectively, with related structure a…


Aktuelle smitsomme sygdomme (5)

30.06.2017
Salmonella -- United StatesFoodborne salmonellosis causes an estimated one million illnesses and 400 deaths annually in the USA (1). _Salmonella [enterica_ serotype] Anatum is one of the top 20 Salmonella serotypes in the USA. During 2013-2015 t…

16.05.2017
Other Plant Disease -- United KingdomPepino mosaic virus (PepMV) is one of the most economically important diseases of tomatoes. There are known to be 3 strains present on UK crops. Fruit infected with multiple strains of the virus experience mo…

3.03.2017
Other Plant Disease -- VietnamThe farmers in Dak Nong Province will have to bear huge losses as thousands of pepper trees suddenly died just before they were harvested. Farmers have to destroy most of the trees because of disease.A farmer [s…

6.09.2016
…ely 40 Milton-Union Middle School students were treated on Friday [2 Sep 2016] by medics after they ingested suspected ghost peppers at the school, officials said.The incident happened during the lunch period, and the district was still working t…

13.08.2016
Rabies -- South AfricaIn response to the RFI (request for information) sent to EpiCore members in South Africa, we received the following information:The 2 people were receiving post-exposure prophylaxis, according to contacts in the NICD [N…