Søgning på udtrykket 'pep' giver 43 resultater
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Dokumenter [1]
Version: 3. Endelig guideline: 01.09.2020. Guideline skal revideres senest: 01.09.2023
Arbejdsgruppens medlemmer: Peer Brehm Christensen, Christian Erikstrup, Jan Gerstoft, Terese Katzenstein, Alex Laursen, Suzanne Lunding, Birgitte Mørn og Nina Weis.
Sider [1]
fected Host: Epidemiology and Pathogenesis in the Antiretroviral Era Curr HIV/AIDS Rep. 2015; 12: 6?15.
HIV - persistence on ART & cure research:. Margolis et al: Latency reversal and viral clearance to cure HIV-1. Science. 2016; 253: aaf6517.
PREP og PEP:. Fonner et al. Effectiveness and safety of oral HIV preexposure prophylaxis for all populations: AIDS 2016 Jul 31;30(12):1973-83. Rodger et al. Sexual Activity Without Condoms and Risk of HIV Transmission in Serodifferent Couples When the HIV-Positive
Kalender [1]
25. november 2019, Auditorium 3 og 4, Hvidovre Hospital
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Clinical Infectious Diseases
19.03.2024
BMJ Open
15.03.2024
. Objective. Dipeptidase-1 (DPEP-1) is a recently discovered leucocyte adhesion receptor for neutrophils and monocytes in the lungs and kidneys and serves as a potential therapeutic target to attenuate inflammation in moderate-to-severe COVID-19. We aimed to evaluate the safety and efficacy of the DPEP-1 inhibitor, LSALT peptide, to prevent specific organ dysfunction in patients hospitalised with COVID-19. . Design. Phase 2a randomised, placebo-controlled, double-blinded, trial. . Setting. Hospitals in Ca
BMJ Open
15.03.2024
. Objective. Dipeptidase-1 (DPEP-1) is a recently discovered leucocyte adhesion receptor for neutrophils and monocytes in the lungs and kidneys and serves as a potential therapeutic target to attenuate inflammation in moderate-to-severe COVID-19. We aimed to evaluate the safety and efficacy of the DPEP-1 inhibitor, LSALT peptide, to prevent specific organ dysfunction in patients hospitalised with COVID-19. . Design. Phase 2a randomised, placebo-controlled, double-blinded, trial. . Setting. Hospitals in Ca
BMJ Open
15.03.2024
. Objective. Dipeptidase-1 (DPEP-1) is a recently discovered leucocyte adhesion receptor for neutrophils and monocytes in the lungs and kidneys and serves as a potential therapeutic target to attenuate inflammation in moderate-to-severe COVID-19. We aimed to evaluate the safety and efficacy of the DPEP-1 inhibitor, LSALT peptide, to prevent specific organ dysfunction in patients hospitalised with COVID-19. . Design. Phase 2a randomised, placebo-controlled, double-blinded, trial. . Setting. Hospitals in Ca
Journal of Medical Virology
7.03.2024
Journal of Medical Virology, Volume 96, Issue 3, March 2024.
Antimicrobial Agents And Chemotherapy
29.02.2024
Antimicrobial Agents and Chemotherapy, Ahead of Print.
Antimicrobial Agents And Chemotherapy
22.02.2024
Antimicrobial Agents and Chemotherapy, Ahead of Print.
BMC Infectious Diseases
21.02.2024
Abstract. . Background. Leprosy is an infectious disease with a slow decline in global annual caseload in the past two decades. Active case finding and post-exposure prophylaxis (PEP) with a single dose of rifampicin (SDR) are recommended by the World Health Organization as measures for leprosy elimination. However, more potent PEP regimens are needed to increase the effect in groups highest at risk (i.e., household members and blo
Proceedings of the National Academy of Sciences
7.02.2024
Proceedings of the National Academy of Sciences, Volume 121, Issue 6, February 2024.
Proceedings of the National Academy of Sciences: Immunology and Inflammation
3.02.2024
Proceedings of the National Academy of Sciences, Volume 121, Issue 6, February 2024.
Proceedings of the National Academy of Sciences
31.01.2024
Proceedings of the National Academy of Sciences, Volume 121, Issue 5, January 2024.
PLoS One Infectious Diseases
23.01.2024
, David S. Courson, Myriam L. Cotten, Erin B. Purcell . The spore-forming intestinal pathogen Clostridioides difficile causes multidrug resistant infection with a high rate of recurrence after treatment. Piscidins 1 (p1) and 3 (p3), cationic host defense peptides with micromolar cytotoxicity against C. difficile, sensitize C. difficile to clinically relevant antibiotics tested at sublethal concentrations. Both peptides bind to Cu2+ using an amino terminal copper and nickel binding motif. Here, we investiga
Journal of Medical Virology
19.01.2024
Journal of Medical Virology, Volume 96, Issue 1, January 2024.
BMJ Open
22.12.2023
. Objectives. This study examined whether the US President’s Emergency Plan for AIDS Relief (PEPFAR) funding had effects beyond HIV, specifically on several measures of maternal and child health in low-income and middle-income countries (LMICs). The results of previous research on the question of PEPFAR health spillovers have been inconsistent. This study, using a large, multicountry panel data set of 157 LMICs including 90 recipient countries, adds to the literature. . Design. Seven indicators including
Virulence
28.11.2023
Volume 14, Issue 1, December 2023 .
PLoS One Infectious Diseases
28.11.2023
metagenomic information of the activated sludge (AS) microbiome, which is thought to contain unutilized biological resources. We first performed genome-resolved metagenomics for AS taken from a municipal sewage treatment plant and obtained 97 nonribosomal peptide synthetase (NRPS)/polyketide synthase (PKS)-related gene sequences from 43 metagenomic assembled bins, most of which were assigned to the phyla Proteobacteria and Myxococcota. Furthermore, these NRPS/PKS-related genes are predicted to be novel beca
Infection and Immunity
27.11.2023
Infection and Immunity, Ahead of Print.
International Journal of Infectious Diseases
26.11.2023
During the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), different vaccines have been successfully developed [1-3]. Although neutralizing antibodies provide the first line of antiviral defense [4, 5], spike-specific antibody titers tend to wane quickly and show limited neutralizing activity against newly arising variants of concern (VOCs) [6]. In contrast, T cells were shown to mediate long-term immunity that is largely conserved ag
Journal of the American Medical Association
15.11.2023
This Viewpoint discusses the importance of the US Congress reauthorizing funding for the President’s Emergency Plan for AIDS Relief, a program developed in 2003 that has played a critical role in fighting HIV/AIDS worldwide as well as other emerging infections and noncommunicable diseases.
Proceedings of the National Academy of Sciences
2.11.2023
Proceedings of the National Academy of Sciences, Volume 120, Issue 44, October 2023.
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Medscape Infectious Diseases
6.03.2024
Postexposure prophylaxis with doxycycline reduced some sexually transmitted infection rates in half in certain populations but concerns about antibiotic resistance remain. . Medscape Medical News
Medscape Infectious Diseases
19.05.2023
Those antibiotics may kill 99.9% of germs, but what about the 0.1% that gets left behind? . MDedge News
ProMED
5.04.2023
Rabies -- United StatesAbstract--------Background: No rabies post-exposure prophylaxis (PEP) failure has been documented in humans in the United States using modern cell-culture vaccines. In January 2021, an 84 year old male died from rabies 6 months after being bitten by a rabid bat despite receiving timely rabies post-exposure prophylaxis (PEP). We investigated the cause of breakthrough infection.Methods: We reviewed medical records, laboratory results, and autopsy findings, and performed whole genome
ProMED
1.04.2023
Botulism -- CanadaKomera Original / Seasoned Hot Pepper Sauce / 148 mL / 6 27987 43939 7 All units sold up to and including 30 Mar 2023As of the posting of this recall, there have been no reported illnesses associated with the consumption of this product.The symptoms of botulism may include some or all of the following: double vision, blurred vision, drooping eyelids, slurred speech, difficulty swallowing, difficulty breathing, a thick-feeling tongue, dry mouth, and muscle weakness. People with botulism
Eurosurveillance latest updates
16.03.2023
An individualised blood donor selection policy was implemented in the United Kingdom from summer 2021. We have investigated the impact of this policy by comparing the extent of undeclared use of HIV pre-exposure or post-exposure prophylaxis (PrEP/PEP) before and after this change. The rate of PrEP usage in syphilis-positive male blood donors has not changed since individualised donor assessment was implemented but provides continuing evidence of undisclosed PrEP use which may be associated with current or p
Medscape Infectious Diseases
24.02.2023
Postexposure prophylaxis with doxycycline has been shown to significantly reduce the risk of STIs in men and transgender women. Now a study looks at its efficacy in cisgender women taking HIV PrEP. . Medscape Medical News
Morbidity and Mortality Weekly Report (MMWR)
14.07.2022
This report describes HIV testing among children and adolescents in PEPFAR-supported countries during the COVID-19 pandemic.
ProMED
21.04.2022
Botulism -- United States
Morbidity and Mortality Weekly Report (MMWR)
24.03.2022
This report describes programmatic gains of HIV treatment during the pandemic.
Morbidity and Mortality Weekly Report (MMWR)
24.11.2021
This report describes early sexual debut and associated risks factors among adolescent girls in nine PEPFAR countries.
ProMED
21.07.2021
Other Plant Disease -- RussiaA 20-ton consignment of Uzbek fresh tomatoes arrived in the Irkutsk region [Russia]. Rosselkhoznadzor [Federal Service for Veterinary and Phytosanitary Surveillance] sent samples for examination. Virological results revealed _Pepino mosaic virus_ by PCR method. The test confirms the presence of a dangerous virus in the product. The virus was detected for the 1st time in Irkutsk region. Currently, there is no means of combating the disease. Preventive measures should be observed
ProMED
1.07.2021
Other Plant Disease -- New ZealandNew Zealand tomato exports to six countries have been stopped, after the _Pepino mosaic virus_ (PepMV) was discovered on crops. The Ministry for Primary Industries (MPI) has notified Australia, Japan, Thailand, Fiji, Tonga, and New Caledonia, because these countries consider PepMV a quarantine risk. The virus was first detected in an Auckland glasshouse and has subsequently been found in tomato production facilities in the wider region. The premises where PepMV has been fou
Morbidity and Mortality Weekly Report (MMWR)
27.05.2021
This report describes the impact of COVID-19 on HIV viral load testing in PEPFAR-supported countries.
ProMED
13.04.2021
Other Plant Disease -- SerbiaDuring a survey on tomato viruses conducted in Serbia, virus-like symptoms were observed in July 2019 in tomato plants (_Solanum lycopersicum_) grown in 2 separate plastic tunnels in Jablanica district. Affected plants showed yellow angular spots on the leaves accompanied by necrosis and distortion, as well as fruit discoloration. In these 2 tomato crops, disease incidence was estimated at 80%. Laboratory analysis (serological, molecular and biological tests) confirmed the pres
Morbidity and Mortality Weekly Report (MMWR)
3.12.2020
This report describes sex differences in human immunodeficiency virus testing in sub-Saharan African countries.
Morbidity and Mortality Weekly Report (MMWR)
27.02.2020
When taken daily, preexposure prophylaxis (PrEP) reduces the risk of acquiring human immunodeficiency virus (HIV). PrEP is an important tool for preventing HIV among persons at substantial risk for HIV infection, including female sex workers, men who have sex with men, transgender women, and persons who inject drugs.
Morbidity and Mortality Weekly Report (MMWR)
27.11.2019
Human immunodeficiency virus (HIV) case-based surveillance continuously and systematically monitors HIV-positive patients throughout their clinical care until death.
Statens Serum Institut
14.12.2017
WHO har 1/12-2017 i en rapport fra Strategic Advisory Group of Experts on Immunization, SAGE, udgivet nye retningslinjer på baggrund af ny evidens om brugen af rabiesvacciner og rabies-immunglobulin (RIG).
Medscape Infectious Diseases
22.07.2023
Is it time to add the antibiotic doxycycline post exposure for more STIs? Doxy-PEP use is a clinical controversy that will be debated at the upcoming International AIDS Society Conference. . Medscape Medical News
Eurosurveillance latest updates
16.06.2023
tbreak of mpox outside endemic areas in 2022, yet few studies have provided information on mpox vaccine effectiveness (VE). . . Aim. To assess VE after one dose of a third-generation smallpox vaccine against mpox when given as post-exposure prophylaxis (PEP) within 14 days. . . Methods. A survival analysis in a prospective cohort of close contacts of laboratory-confirmed mpox cases was conducted from the beginning of the outbreak in the region of Madrid in May 2022. The study included contacts of cases