Sidst opdateret 08.01.2020
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Søgeord (hepatitis c) valgt. Opdateret for 3 timer siden.10 emner vises.
Klebsiella pneumoniae, Tuberculosis, Other Human Disease, HIV/AIDS, Yellow Fever, Hepatitis, E. coli, Dengue, Trichinosis, Gastroenteritis, Staph, Hepatitis B, Pasteurellosis, Zika virus, Chikungunya, Hepatitis C, Pneumonia, Lassa Fever, Meningitis - Neisseria, Mycobacteria, non-TB, Taeniasis, Q Fever -- NepalGeographical variability in anticapsular IgG levels elicited by pneumococcal conjugate vaccines: Implications for clinical protection?Int J Infect Dis. 2020; 92(Mar): 259-260.William P
T. Sonia Boender, Eline Op de Coul, Joop Arends, Maria Prins, Marc van der Valk, Jan T.M. van der Meer, Birgit van Benthem, Peter Reiss and Colette Smit
With regards to the global strategy towards eliminating viral hepatitis, reliable surveillance systems are essential to assess the national response for eliminating hepatitis C virus (HCV).
We aimed to assess the completeness of the two national registries with data on acute HCV infection in people with HIV, and estimated the number of acute HCV infections among adults (aged ≥ 18 years) with HIV in the Netherlands.
In this observational study, cases of HCV infection and reinfection among adults with a positive or unknown HIV-serostatus were identified from 2003 to 2016 in two national registries: the ATHENA cohort and the National Registry for Notifiable Diseases. For 2013–2016, cases were linked, and two-way capture–recapture analysis was carried out.
During 2013–2016, there were an estimated 282 (95% confidence interval (CI): 264–301) acute HCV infections among adults with HIV. The addition of cases with an unknown HIV-serostatus increased the matches (from n = 107 to n = 129), and subsequently increased the estimated total: 330 (95%CI: 309–351). Under-reporting was estimated at 14–20%.
Under-reporting of acute HCV infection among people with HIV could partially be explained by an unknown HIV-serostatus, or by differences in HCV stage (acute or chronic) at first diagnosis. Surveillance data should ideally include both acute and chronic HCV infections, and enable to distinguish these as well as initial- and re-infections. National surveillance of acute HCV can be improved by increased notification of infections.
Coronavirus, Polio, Meningitis, Pneumonia, Tuberculosis, Dengue, Other Human Disease, Typhus, Hepatitis B, Chikungunya, Zika virus, Mumps, Measles, Rubella, Yellow Fever, West Nile Virus, Cytomegalovirus, HIV/AIDS, Malaria, Chagas, Avian Influenza, Legionnaires', Whooping Cough, Hepatitis E, Tick-borne Encephalitis, Hepatitis C -- ChinaThe continuing 2019-nCoV epidemic threat of novel coronaviruses to global health: the latest 2019 novel coronavirus outbreak in Wuhan, China.David S Hui, Esam I Azhar, Tariq A Madani, Francine Ntoumi, Richard Kock, Osman Dar, et al.Int J Infect Dis. 2020; 91(Feb): 264-266.Extra time and penalties in the polio endgame.Melinda Suchard, Oyewale Tomori, Lucille BlumbergInt J Infect Dis. 2020; 91(Feb): 252-254.Original reportsBacterial
Opioid use disorder and hepatitis C virus infection rates significantly increased during 2000-2015 among women delivering in hospitals in the United States.
In April 2015, the country of Georgia, with a high prevalence of hepatitis C virus (HCV) infection (5.4% of the adult population, approximately 150,000 persons), embarked on the world's first national elimination program.
May is Hepatitis Awareness Month, and May 19 is Hepatitis Testing Day. Many people with hepatitis B and hepatitis C remain unaware of their infection until serious complications occur.
Investigation identified an outbreak of at least 12 hepatitis C virus infections in patients who had received opioid injections from a nurse who admitted to diverting injectable narcotic drugs.
The number and proportion of increased risk donors have increased since 2010, likely because of the epidemic of opioid overdose deaths. Compared with standard risk donors, increased risk donors were significantly more likely to have hepatitis B virus and hepatitis C virus infection.
G Ireland, R Simmons, M Hickman, M Ramsay, C Sabin and S Mandal
Liver transplantation is an important measure of burden from hepatitis C virus (HCV)-associated liver disease.
To describe transplant rates and survival in individuals with HCV infection from 2008 to 2017 in England through data linkage.
This is a retrospective observational cohort study. Laboratory reports of HCV infection were linked to the Liver Transplant Registry for individuals aged 15 years and over, first diagnosed between 1998 and 2017. We estimated age-sex standardised incidence rates and used Poisson regression to investigate predictors of liver transplantation and test for a change in incidence after introduction of direct-acting antivirals (DAAs) in 2014. Kaplan-Meier survival analysis was used to calculate post-transplant survival rates.
Of 124,238 individuals diagnosed with HCV infection, 1,480 were registered and 1,217 received a liver transplant. Of individuals registered, 1,395 had post-HCV cirrhosis and 636 had hepatocellular carcinoma (618 also had post-HCV cirrhosis). Median time from HCV diagnosis to transplant was 3.4 years (interquartile range: 1.3–6.8 years). Liver transplant rates were lower 2014–17 compared with 2011–13 (incidence rate ratio: 0.64; 95% confidence interval: 0.55–0.76). Survival rates were 93.4%, 79.9% and 67.9% at 1, 5 and 10 years, respectively. Data linkage showed minimal under-reporting of HCV in the transplant registry.
In the post-DAA era, liver transplant rates have fallen in individuals with HCV infection, showing early impact of HCV treatment scale-up; but the short time from HCV diagnosis to liver transplant suggests late diagnosis is a problem.
The US Food and Drug Agency has warned that three direct-acting antiviral drugs have been associated with rare cases of severe liver injury in patients being treated for hepatitis C virus infection.
Clinical Immunology Society (CIS) annual meeting 2020
Denver, Colorado, USA
2.04.2020 - 5.04.2020
International Liver Congress (ILC) 2020
15.04.2020 - 19.04.2020
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 2020
18.04.2020 - 21.04.2020
DSI årsmøde 2020 (aflyst)
Hindsgavl Slot, Middelfart
1.05.2020 - 2.05.2020
Kursus i rejsemedicin 2020
Statens Serum Institut
4.05.2020 - 6.05.2020
COVID-19 retningslinje (2020)
National handlingsplan for antibiotika til mennesker (2017)
Retningslinjer til sundhedsprofessionelle vedr. håndtering af infektion med zikavirus (2019)
Antiviral behandling af hiv smittede personer (2019)
Clinical Features and Short-term Outcomes of 102 Patients with Corona Virus Disease 2019 in Wuhan, China
2.04.2020Clinical Infectious Diseases Advance Access
A randomized clinical trial to compare P. falciparum gametocytaemia and infectivity following blood-stage or mosquito bite induced controlled malaria infection
2.04.2020The Journal of Infectious Diseases Advance Access
Vertical transmission of gut microbiome and antimicrobial resistance genes in infants exposed to antibiotics at birth
2.04.2020The Journal of Infectious Diseases Advance Access
Safeguard research in the time of COVID-19
Modelling COVID-19 transmission: from data to intervention
2.04.2020The Lancet Infectious Diseases
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