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Avian Influenza H5N6 -- ChinaChina's agriculture ministry said on [Thu 16 Jan 2020] it had found a new case of highly pathogenic H5N6 avian flu in a flock of about 150 wild swans in the western Xinjiang region.One had died and another was sick, it said in a statement on its website.The ministry reported a case of the same strain of bird flu in swans in the region last week [week of 6 Jan 2020].--Communicated by:ProMED-mail[A highly pathogenic avian influenza (HPAI) subtype H5N6 was detected in wild
Avian Influenza H5N8 -- HungaryInformation received on [and dated] 15 Jan 2020 from Dr Lajos Bognar, Deputy State Secretary Chief Veterinary Officer, Food Chain Safety Department, Ministry of Agriculture, Budapest, HungarySummaryReport type: immediate notificationDate of start of the event: 10 Jan 2020Date of confirmation of the event: 14 Jan 2020Report date: 15 Jan 2020Date submitted to OIE: 15 Jan 2020Reason for notification: recurrence of a listed diseaseDate of previous occurrence: 24 Apr
Avian Influenza H5N8 -- RomaniaInformation received on [and dated] on 14 Jan 2020 from Dr Robert Viorel Chioveanu, President, Secretary of State, Chief Veterinary Officer, Veterinary Services, National Sanitary Veterinary and Food Safety Authority, Bucharest, RomaniaSummaryReport type: immediate notificationDate of start of the event: 13 Jan 2020Date of confirmation of the event: 14 Jan 2020Report date: 14 Jan 2020Date submitted to OIE: 14 Jan 2020Reason for notification: recurrence of a listed diseaseDate
Influenza season is still in full swing and children are especially hard hit, in part as a result of a vaccine that is poorly matched to the currently predominant strain.
Avian Influenza H5N8 -- HungaryThe H5N8 bird flu virus has been detected at a farm outside Acs, in Komarom-Esztergom county, national food safety authority Nebih said on Monday [12 Jan 2020].The chief public health officer has ordered that the entire stock of the farm, over 53 000 turkeys, should be culled and that poultry be kept indoors across the country, Nebih said.Nebih also said that the H5N8 strain has not spread to humans in Europe, and poultry products are safe to eat.Nebih has started monitoring
Avian Influenza H5N6 -- ChinaInformation received on [and dated] 10 Jan 2020 from Dr Huang Baoxu, Secretary of the Party Leadership Group, Animal Health and Epidemiology Centre, Ministry of Agriculture and Rural Affairs, Qingdao, China (People's Rep. of)SummaryReport type: immediate notificationDate of start of the event: 29 Dec 2019Date of confirmation of the event: 8 Jan 2020Report date: 10 Jan 2020Date submitted to OIE: 10 Jan 2020Reason for notification: recurrence of a listed diseaseDate of previous
Avian Influenza H5N8 -- SlovakiaInformation received on [and dated] 10 Jan 2020 from Dr. Jozef Bires, Director & Chief Veterinary Officer, State Veterinary and Food Administration, Ministry of Agriculture, Bratislava, SlovakiaSummaryReport type: Immediate notificationDate of start of the event: 9 Jan 2020Date of confirmation of the event: 9 Jan 2020Report date: 10 Jan 2020Date submitted to OIE: 10 Jan 2020Reason for notification: Recurrence of a listed diseaseDate of previous occurrence: 22 May 2017Causal
Other Human Disease -- CanadaHealth officials are asking visitors to stay away from Talarico Place [extended care home in Castlegar, British Columbia] as they are trying to contain a respiratory infection outbreak at the facility.Interior Health declared the outbreak at the extended care home on [27 Dec 2019] and expects it to be a bit longer before the status changes. 2 incubation periods of 4 to 14 days (depending on the infection's cause) must pass with no new cases before the outbreak can be declared
This report describes CDC's and Louisiana health officials' investigation of the state's early and intense flu activity in the fall of 2019
Jeffrey C Kwong, Hannah Chung, James KH Jung, Sarah A Buchan, Aaron Campigotto, Michael A Campitelli, Natasha S Crowcroft, Jonathan B Gubbay, Timothy Karnauchow, Kevin Katz, Allison J McGeer, J Dayre McNally, David C Richardson, Susan E Richardson, Laura C Rosella, Kevin L Schwartz, Andrew Simor, Marek Smieja, George Zahariadis and on behalf of the Canadian Immunization Research Network (CIRN) investigators
Annual influenza vaccination is recommended for older adults, but evidence regarding the impact of repeated vaccination has been inconclusive.
We investigated vaccine effectiveness (VE) against laboratory-confirmed influenza and the impact of repeated vaccination over 10 previous seasons on current season VE among older adults.
We conducted an observational test-negative study in community-dwelling adults aged > 65 years in Ontario, Canada for the 2010/11 to 2015/16 seasons by linking laboratory and health administrative data. We estimated VE using multivariable logistic regression. We assessed the impact of repeated vaccination by stratifying by previous vaccination history.
We included 58,304 testing episodes for respiratory viruses, with 11,496 (20%) testing positive for influenza and 31,004 (53%) vaccinated. Adjusted VE against laboratory-confirmed influenza for the six seasons combined was 21% (95% confidence interval (CI): 18 to 24%). Patients who were vaccinated in the current season, but had received no vaccinations in the previous 10 seasons, had higher current season VE (34%; 95%CI: 9 to 52%) than patients who had received 1–3 (26%; 95%CI: 13 to 37%), 4–6 (24%; 95%CI: 15 to 33%), 7–8 (13%; 95%CI: 2 to 22%), or 9–10 (7%; 95%CI: −4 to 16%) vaccinations (trend test p = 0.001). All estimates were higher after correcting for misclassification of current season vaccination status. For patients who were not vaccinated in the current season, residual protection rose significantly with increasing numbers of vaccinations received previously.
Although VE appeared to decrease with increasing numbers of previous vaccinations, current season vaccination likely provides some protection against influenza regardless of the number of vaccinations received over the previous 10 influenza seasons.
Influenza -- Bangladesh- If you get very sick, are pregnant, or are 65 years or older, or are otherwise at high risk of flu-related complications, call your doctor. You might need antiviral drugs to treat flu.- Stay at home and rest.- Avoid close contact with well people in your house so you won't make them sick.- Drink plenty of water and other clear liquids to prevent fluid loss (dehydration).When caring for people who have the flu---------------------------------------- Avoid being face to face with
Avian Influenza -- United KingdomThe authorities are investigating a suspected case of a notifiable bird disease on a poultry farm in County Fermanagh. It was discovered 4 days ago [4 Jan 2020] when a vet became concerned about increased mortality among the broiler birds.Tests are being run to see if it is bird flu or another disease called Newcastle disease. It will be several days before final results are back. Restrictions have been put in place on the farm as a precautionary measure.The Department of Agriculture
Avian Influenza H5N1 -- IndiaInformation received on [and dated] 8 Jan 2020 from Dr Atul Chaturvedi, secretary, Department of Animal Husbandry and Dairying, Ministry of Fisheries, Animal Husbandry and Dairying, New Delhi, IndiaSummaryReport type: immediate notificationDate of start of the event: 7 Dec 2019Date of confirmation of the event: 23 Dec 2019Reason for notification: recurrence of a listed diseaseDate of previous occurrence: 2 Sep 2019Manifestation of disease: clinical diseaseCausal agent: highly
Avian Influenza H5N8 -- PolandSummary of the epizootic situation associated with highly pathogenic avian influenza (HPAI) in poultry during the period 31 Dec 2019-3 Jan 2020.Based on the results of tests received from the national reference laboratory for avian influenza, i.e. the National Veterinary Institute - National Research Institute in Pulawy, a total of 7 new outbreaks of HPAI H5N8 have been confirmed in poultry during the said period, of which 3 were in 2019 and 4 in 2020.Outbreak No. 2019/1 involved a
Influenza-like illness activity is on the rise and 800 deaths were reported in the last week alone; the illness has killed at least 2900 so far this season.
Avian Influenza H5N8 -- Worldwide/UnknownInformation received on [and dated] 2 Jan 2020 from Dr Bogdan Konopka, Chief Veterinary Officer, Ministry of Agriculture and Rural Development, General Veterinary Inspectorate, Warszaw, PolandSummaryReport type: immediate notificationDate of start of the event: 30 Dec 2019Date of confirmation of the event: 31 Dec 2019Report date: 2 Jan 2020Date submitted to OIE: 2 Jan 2020Reason for notification: recurrence of a listed diseaseDate of previous occurrence: 20 Apr 2017Causal
Tuberculosis, Antimicrobial resistance, Other Human Disease, Pneumonia, Respiratory Syncytial Virus, Q Fever, HIV/AIDS, Measles, Influenza, Dengue, Hepatitis B, Hantavirus, Gastroenteritis, Schistosomiasis, Leishmaniasis, Chikungunya, Rickettsia -- SyriaFrequent testicular involvement in multibacillary leprosyHendra Gunawan, Pati Aji Achdiat, Rachel Marsella Rahardjo, Reti Hindritiani, Oki SuwarsaInternational Journal of Infectious Diseases, Volume 90, January 2020, pp. 60-64Antibiotic use among hospitalized adult patients in a setting with limited laboratory infrastructure in Freetown Sierra Leone, 2017-2018Sulaiman Lakoh, Olukemi Adekanmbi, Darlinda F. Jiba, Gibrilla F. Deen, Wadzani Gashau, Stephen Sevalie, Eili Y.
Influenza activity has been above the national baseline for the past 7 weeks, and the number of children who have died is twice as high as last season at this time.
Influenza -- Worldwide/UnknownInformation in this report is categorized by influenza transmission zones, which are geographical groups of countries, areas or territories with similar influenza transmission patterns.Summary------------- In the temperate zone of the northern hemisphere, respiratory illness indicators and influenza activity continued to increase in most countries.- In the Caribbean and Central American countries, influenza activity was low overall, except for Cuba, where increased detections of
Avian Influenza H5N6 -- NigeriaThe URL of the OIE report published by ProMED-mail on 29 Nov 2019, archive number http://promedmail.org/post/20191129.6802815, is no longer available. On 23 Dec 2019, Nigeria sent a new immediate notification to the OIE replacing the report sent in November.The epidemiological comments made in this latest OIE report noted: "The original report submitted [on 27 Nov 2019] for highly pathogenic avian influenza (HPAI) with OIE reference number 32493 was deleted and replaced with the report
Avian Influenza H5N6 -- NigeriaInformation received on [and dated] 23 Dec 2019 from Dr Olaniran Alabi, director, chief veterinary officer, Veterinary and Pest Control Services, Federal Ministry of Agriculture and Rural Development, Abuja, NigeriaSummaryReport type: immediate notificationDate of start of the event: 25 Jun 2019Date of confirmation of the event: 27 Nov 2019Reason for notification: new strain of a listed disease in the countryCausal agent: highly pathogenic avian influenza virusSerotype:
Influenza continues to spread across the United States; reports of nine pediatric deaths were reported to the CDC this week, bringing this year's total to 19.
Timely state- or local-level estimates of the number of persons who are ill and seek medical care due to influenza (flu) contribute to preparedness and communication messages needed during flu season and in the event of a flu pandemic.
Thanks to adaptive immunity, exposure to a seasonal influenza virus may decrease the risk of coming down with a cold.
Influenza activity has been at or above the national baseline for 5 weeks and at least 1300 influenza-related deaths have occurred.
Favipiravir and oseltamivir were more effective for severe influenza than oseltamivir alone, a study found.
Influenza -- Worldwide/UnknownSummary- In the temperate zone of the northern hemisphere, respiratory illness indicators and influenza activity started to increase in most countries. Influenza activity was elevated across the countries in Western Asia.- In the Caribbean and Central American countries, influenza activity was low overall, except for Jamaica and Honduras. In tropical South American countries, influenza activity remained low.- In tropical Africa, influenza activity remained elevated in some countries of
Influenza H3N2 -- CanadaDate: Wed 11 Dec 2019From: Scott Weese [edited]The recent ProMED post about canine influenza in Ontario appears to be incorrect. The cited news report has verbatim text from January 2018 articles describing the previous outbreak (full details at ). I am unaware of any canine influenza activity in Canada since October 2018.--J Scott Weese DVM DVSc DipACVIMOntario Veterinary College and Centre for Public Health and ZoonosesUniversity of GuelphGuelph,
Avian Influenza -- ChinaFirst reported by WHO/WPRO:1. Avian Influenza Weekly Update Number 716; 22 Nov 2019 #5 [CHP Fujian Province: A 4-year-old girl with onset on 26 Oct 2019].2. Avian Influenza Weekly Update Number 717; 29 Nov 2019 #6 [CHP Anhui Province: A 5-year-old girl with onset on 12 Nov 2019].Hong Kong Centre for Health Protection (CHP):3. Avian Influenza Report, 15(49); reporting period: 1 Dec-7 Dec 2019 (week 49) (Published 10 Dec 2019)Taiwan Centers for Disease Control:4. Mainland
Canine Influenza -- CanadaThe public health authority in southern Ontario says it has confirmed what they believe to be the 1st 2 known cases of canine influenza in Canada.The H3N2 strain of the virus was detected by a veterinarian in dogs imported by an adoption agency from South Korea via the United States."A small number of dogs having close with the affected dogs also have mild respiratory disease, but test results from those animals are not yet available," the health unit said in a press
Avian Influenza H5N6 -- NigeriaInformation received on [and dated] 27 Nov 2019 from Dr Olaniran Alabi, director, chief veterinary officer, Veterinary and Pest Control Services, Federal Ministry of Agriculture and Rural Development, Abuja, NigeriaSummaryReport type: immediate notificationDate of start of the event: 25 Jun 2019Date of confirmation of the event: 27 Nov 2019Reason for notification: new strain of a listed disease in the countryCausal agent: highly pathogenic avian influenza virusSerotype:
Esther Kissling, Francisco Pozo, Silke Buda, Ana-Maria Vilcu, Alin Gherasim, Mia Brytting, Lisa Domegan, Verónica Gómez, Adam Meijer, Mihaela Lazar, Vesna Višekruna Vučina, Ralf Dürrwald, Sylvie van der Werf, Amparo Larrauri, Theresa Enkirch, Joan O’Donnell, Raquel Guiomar, Mariëtte Hooiveld, Goranka Petrović, Elena Stoian, Pasi Penttinen, Marta Valenciano and I-MOVE primary care study team
Influenza A(H3N2) clades 3C.2a and 3C.3a co-circulated in Europe in 2018/19. Immunological imprinting by first childhood influenza infection may induce future birth cohort differences in vaccine effectiveness (VE).
The I-MOVE multicentre primary care test-negative study assessed 2018/19 influenza A(H3N2) VE by age and genetic subgroups to explore VE by birth cohort.
We measured VE against influenza A(H3N2) and (sub)clades. We stratified VE by usual age groups (0–14, 15–64, ≥ 65-years). To assess the imprint-regulated effect of vaccine (I-REV) hypothesis, we further stratified the middle-aged group, notably including 32–54-year-olds (1964–86) sharing potential childhood imprinting to serine at haemagglutinin position 159.
Influenza A(H3N2) VE among all ages was −1% (95% confidence interval (CI): −24 to 18) and 46% (95% CI: 8–68), −26% (95% CI: −66 to 4) and 20% (95% CI: −20 to 46) among 0–14, 15–64 and ≥ 65-year-olds, respectively. Among 15–64-year-olds, VE against clades 3C.2a1b and 3C.3a was 15% (95% CI: −34 to 50) and −74% (95% CI: −259 to 16), respectively. VE was −18% (95% CI: −140 to 41), −53% (95% CI: −131 to −2) and −12% (95% CI: −74 to 28) among 15–31-year-olds (1987–2003), 32–54-year-olds (1964–86) and 55–64-year-olds (1954–63), respectively.
The lowest 2018/19 influenza A(H3N2) VE was against clade 3C.3a and among those born 1964–86, corresponding to the I-REV hypothesis. The low influenza A(H3N2) VE in 15–64-year-olds and the public health impact of the I-REV hypothesis warrant further study.
Alyson A Kelvin and Maria Zambon
Influenza -- Worldwide/UnknownInformation in this report is categorized by influenza transmission zones, which are geographical groups of countries, areas, or territories with similar influenza transmission patterns.Summary-------- In the temperate zone of the northern hemisphere, influenza activity remained at interseasonal levels in most countries. However, influenza activity continued to increase across the countries in western Asia.- In the Caribbean and tropical South American countries, influenza activity
Levels of influenza-like illness activity have exceeded the baseline for 2 weeks running, according to the latest report from the Centers for Disease Control and Prevention.
Avian Influenza -- ChinaInformation received on [and dated] 20 Nov 2019 from Dr Wen-Jane Tu, Chief Veterinary Officer, Deputy Director General, Bureau of Animal and Plant Health Inspection and Quarantine, Council of Agriculture, Executive Yuan, Taipei, Chinese Taipei [Taiwan]SummaryReport type: immediate notificationDate of start of the event: 27 Oct 2019Date of confirmation of the event: 30 Oct 2019Report date: 20 Nov 2019Date submitted to OIE: 20 Nov 2019Reason for notification: recurrence of a
Equine Influenza -- United StatesOn 11 Oct 2019, an attending veterinarian confirmed 2 Ventura County horses tested positive for equine influenza. The 1st, a 2-year-old Warmblood gelding, experienced onset of clinical signs, including coughing, fever, and nasal discharge, on 8 Oct 2019.The 2nd, a yearling filly, first showed clinical signs of coughing, enlarged submandibular (under the jaw) lymph nodes, fever, and nasal discharge on 9 Oct 2019.The vaccination status of both horses is reported as unknown, and both are
As rates of influenza increase, providers evaluating patients with respiratory illnesses should ask them about e-cigarette, or vaping, product use.
Danuta M Skowronski, Suzana Sabaiduc, Siobhan Leir, Caren Rose, Macy Zou, Michelle Murti, James A Dickinson, Romy Olsha, Jonathan B Gubbay, Matthew A Croxen, Hugues Charest, Nathalie Bastien, Yan Li, Agatha Jassem, Mel Krajden and Gaston De Serres
The Canadian Sentinel Practitioner Surveillance Network reports vaccine effectiveness (VE) for the 2018/19 influenza A(H3N2) epidemic.
To explain a paradoxical signal of increased clade 3C.3a risk among 35–54-year-old vaccinees, we hypothesise childhood immunological imprinting and a cohort effect following the 1968 influenza A(H3N2) pandemic.
We assessed VE by test-negative design for influenza A(H3N2) overall and for co-circulating clades 3C.2a1b and 3C.3a. VE variation by age in 2018/19 was compared with amino acid variation in the haemagglutinin glycoprotein by year since 1968.
Influenza A(H3N2) VE was 17% (95% CI: −13 to 39) overall: 27% (95% CI: −7 to 50) for 3C.2a1b and −32% (95% CI: −119 to 21) for 3C.3a. Among 20–64-year-olds, VE was −7% (95% CI: −56 to 26): 6% (95% CI: −49 to 41) for 3C.2a1b and −96% (95% CI: −277 to −2) for 3C.3a. Clade 3C.3a VE showed a pronounced negative dip among 35–54-year-olds in whom the odds of medically attended illness were > 4-fold increased for vaccinated vs unvaccinated participants (p
Theodore Lytras, Stefanos Bonovas, Georgios K. Nikolopoulos and Sotirios Tsiodras
Mark Reacher, Neville Q. Verlander, Maria Zambon and on behalf of the authors of the original article
Tuberculosis, Whooping Cough, Yellow Fever, Hand, Foot and Mouth Disease, Antimicrobial resistance, Influenza, Chagas, Hepatitis B, HIV/AIDS, Other Human Disease, Rabies -- Worldwide/UnknownPertussis in the Association of Southeast Asian Nations: epidemiology and challengesUsa Thisyakorn, Terapong Tantawichien, Chule Thisyakorn, Philippe BuchyInternational Journal of Infectious Diseases, Volume 86, September 2019, pp. 75-83Anti-PcrV titers in non-cystic fibrosis patients with _Pseudomonas aeruginosa_ respiratory tract infectionKentaro Nagaoka, Yu Yamashita, Hirokazu Kimura, Hiroki Kimura, Masaru Suzuki, Tatsuya Fukumoto, Kasumi Hayasaka, Mari Yoshida, Takafumi Hara,
Influenza and pertussis cause substantial disease burden among pregnant women and infants too young to be vaccinated.
During May 19-September 28, 2019, low levels of influenza activity were reported in the United States.
During an influenza pandemic and during seasonal epidemics, more persons have symptomatic illness without seeking medical care than seek treatment at doctor's offices, clinics, and hospitals.
The 2018-19 influenza season was a moderate severity season with two waves of influenza A activity in the United States.
During July 11, 2018-March 29, 2019, in the United States, the Vaccine Adverse Event Reporting System received 125 reports of 192 patients receiving expired inactivated influenza vaccine during the 2018-19 influenza season.
Influenza activity in the United States remained elevated through February 2, 2019, and is expected to continue for several more weeks. Compared with recent influenza seasons, as of February 2, 2019, severity this season has been low, with a lower percentage of outpatient visits for influenza-like illness, lower rates of hospitalization, and fewer deaths attributed to pneumonia and influenza.
On the basis of data from the U.S. Influenza Vaccine Effectiveness Network on 3,254 children and adults with acute respiratory illness during November 23, 2018-February 2, 2019, the overall estimated effectiveness of seasonal influenza vaccine for preventing medically attended, laboratory-confirmed influenza virus infection was 47%.
The U.S. 2017-18 influenza season was a high-severity season, with the highest number of outpatient visits for influenza-like illness since the 2009-10 pandemic and the highest rate of influenza-associated hospitalizations since the system expanded to include adult hospitalizations during the 2005-06 season.
Specialespecifikt kursus om immundefekt og feber af ukendt årsag
28.01.2020 - 29.01.2020
International Congress on Infectious Diseases (ICID) 2020
Kuala Lumpur, Malaysia
20.02.2020 - 23.02.2020
Dansk Selskab for Intern Medicin (DSIM) årsmøde og overrækkelse af Hagedorn prisen 2020
Novo Nordisk Fonden, Tuborg Havnevej 19, 2900 Hellerup
Conference on Retroviruses and Opportunistic Infections (CROI) 2020
Boston, Massachusetts, USA
8.03.2020 - 11.03.2020
Når CROI går i fisk - med transmissioner fra CROI 2020
10.03.2020 - 11.03.2020
Retningslinjer til sundhedsprofessionelle vedr. håndtering af infektion med zikavirus (2019)
Antiviral behandling af hiv smittede personer (2019)
Lumbalpunktur af patienter i blodfortyndende behandling (2019)
Single dose of Doxycycline for the prevention of TBRF
19.01.2020Clinical Infectious Diseases Advance Access
Characteristics of invasive pneumococcal disease (IPD) caused by emerging serotypes after the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) in England; prospective observational cohort study, 2014-18
19.01.2020Clinical Infectious Diseases Advance Access
The effect of therapeutic drug monitoring of beta-lactam and fluoroquinolones on clinical outcome in critically ill patients: the DOLPHIN trial protocol of a multi-centre randomised controlled trial
17.01.2020Latest Results for BMC Infectious Diseases
Fatal hemorrhagic varicella in a patient with abdominal pain: a case report
17.01.2020Latest Results for BMC Infectious Diseases
Antifungal resistance in patients with Candidaemia: a retrospective cohort study
17.01.2020Latest Results for BMC Infectious Diseases
Hvorfor anbefaler Professor Jens Lundgren artiklen"Dolutegravir plus Two Different Prodrugs of Tenofovir to Treat HIV."?
Hvad synes Professor Troels Lillebæk om"The global prevalence of latent tuberculosis: a systematic review and meta-analysis."?
Hvad mener Professor Lars Østergaard om artiklen"Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial."?
Hvad synes Professor Thomas Benfield om"Oral versus Intravenous Antibiotics for Bone and Joint Infection."?
Hvorfor anbefaler Professor Niels Obel artiklen"Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis."?
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