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In January 2018, the Indiana State Department of Health was notified of a case of Cronobacter sakazakii meningitis in an infant who had been fed exclusively maternal milk.
Sindy Böttcher, Sabine Diedrich, Kathrin Keeren and the Laboratory Network for Enterovirus Diagnostic (LaNED)
We report on the increased circulation of enterovirus A71 in Germany in 2019. Strains were mainly identified in hospitalised patients with suspected aseptic meningitis/encephalitis. Molecular analysis showed co-circulation of EV-A71 sub-genogroups C1 and C4, a signal for physicians and public health authorities to include/intensify EV diagnostic in patients showing signs of aseptic meningitis, encephalitis or acute flaccid paralysis/myelitis.
Meningitis - Neisseria -- United KingdomZumla A, Memish ZAEditorial---------On 22 Jul , Public Health England issued an important public health announcement, the unusual occurrence in the UK of 3 people with non-groupable meningococcal infections connected with recent travel to Mecca, Saudi Arabia (1). Two presented with conjunctivitis just days after returning from a pilgrimage. The 3rd person, who was a close contact of one case but had not travelled to Mecca, developed invasive meningococcal disease (1). _Neisseria
Claudia Paredes-Esquivel, Jessica Sola, Sofía Delgado-Serra, Miguel Puig Riera, Nieves Negre, Miguel Ángel Miranda and José A Jurado-Rivera
In October 2018, two Atelerix algirus hedgehogs were admitted to the Wildlife Rehabilitation Hospital in Mallorca (Balearic Islands, Spain) with signs of acute neurological disease. Necropsy detected immature, fully developed nematodes in the subarachnoid space of both hedgehogs, including a gravid female worm. DNA-based molecular tools confirmed the nematode as Angiostrongylus cantonensis, an important aetiological agent of eosinophilic meningitis in humans. So far this zoonotic parasite in has not been reported in western European wildlife.
Viral Meningitis -- BulgariaMosquitoes carry viral meningitis in Bulgaria. There are nearly 1/3 more cases of meningitis since the beginning of the year  than the previous year . The state has allocated another BGN 2 million [USD 1 783 680] to deal with mosquitoes.The disease is not typical for Bulgaria's latitudes, but has started to manifest itself with climate change, said Prof. Dr. Tatyana Chervenyakova of the Infectious Diseases Hospital in Bulgaria. The infection is transmitted through mosquitoes,
Healthcare providers should consider arboviral infections in patients with aseptic meningitis or encephalitis and perform appropriate diagnostic tests, the CDC cautions.
West Nile Virus -- GreeceTwo people over 80 were the 1st victims of West Nile virus in Greece this year , according to the weekly epidemiological surveillance report published by the National Public Health Organization (EODY).From the beginning of epidemiological surveillance until today [2 Aug 2019], 25 cases of West Nile virus infection have been diagnosed and studied in Greece. In 17 of the patients reported, the central nervous system (CNS) was affected (encephalitis and/or meningitis/acute flaccid
Meningitis - Neisseria -- AustraliaThe Department of Health today [25 Jul 2019] reported that an adult is currently recovering after being diagnosed with meningococcal disease serogroup W, bringing the number of reported cases of invasive meningococcal disease in 2019 to 13. Of the 13 cases, 3 have been serogroup B, 5 serogroup W, and 5 serogroup C meningococcal infections.Meningococcal disease is an uncommon, life-threatening illness caused by a bacterial infection of the blood and/or the membranes that line the spinal
Anna Nagy, Eszter Mezei, Orsolya Nagy, Tamás Bakonyi, Nikolett Csonka, Magdolna Kaposi, Anita Koroknai, Katalin Szomor, Zita Rigó, Zsuzsanna Molnár, Ágnes Dánielisz and Mária Takács
During the 2018 WNV transmission season, similarly to other endemic areas in Europe, a large number of human West Nile virus (WNV) infections were reported in Hungary.
We summarise the epidemiological and laboratory findings of the 2018 transmission season and expand experiences in flavivirus differential diagnostics.
Every patient with clinical suspicion of acute WNV infection was in parallel tested for WNV, tick-borne encephalitis virus and Usutu virus (USUV) by serological methods. Sera, whole blood and urine samples were also tested for the presence of viral nucleic acid.
Until the end of December 2018, 215 locally acquired and 10 imported human WNV infections were notified in Hungary. All reported cases were symptomatic; most of them exhibited neurological symptoms. In a large proportion of tested individuals, whole blood was the most appropriate sample type for viral nucleic acid detection, but because whole blood samples were not always available, testing of urine samples also extended diagnostic possibilities. In addition, the first human USUV infection was confirmed in 2018 in a patient with aseptic meningitis. Serological cross-reactions with WNV in different serological assays were experienced, but subsequent molecular biological testing and sequence analysis identified Europe lineage 2 USUV infection.
Careful interpretation and simultaneous application of different laboratory methods are necessary to avoid misdiagnosis of human USUV cases. Expansion of the laboratory-confirmed case definition criteria for detection of viral RNA in any clinical specimens to include urine samples could increase diagnostic sensitivity.
Amoeba -- India1. Sood A, Chauhan S, Chandel L, Jaryal SC. Prompt diagnosis and extraordinary survival from _Naegleria fowleri_ meningitis: A rare case report. Indian J Med Microbiol 2014; 32(2):193-6; .2. Jain R, Prabhakar S, Modi M, Bhatia R, Sehgal R. _Naegleria_ meningitis: a rare survival. Neurol India 2002; 50(4): 470-2; .There have been 5 well-documented survivors in North America: one in the US in 1978, one in Mexico in 2003, 2 additional survivors from the US in 2013, and one from the US in
Viktor Dahl, Karin T Wisell, Christian G Giske, Anders Tegnell and Anders Wallensten
In a study from 2013 that prioritised communicable diseases for surveillance in Sweden, we identified Lyme borreliosis as one of the diseases with highest priority. In 2014, when the present study was designed, there were also plans to make neuroborreliosis notifiable within the European Union.
We compared possibilities of surveillance of neuroborreliosis in Sweden through two different sources: the hospital discharge register and reporting from the clinical microbiology laboratories.
We examined the validity of ICD-10 codes in the hospital discharge register by extracting personal identification numbers for all cases of neuroborreliosis, defined by a positive cerebrospinal fluid–serum anti-Borrelia antibody index, who were diagnosed at the largest clinical microbiology laboratory in Sweden during 2014. We conducted a retrospective observational study with a questionnaire sent to all clinical microbiology laboratories in Sweden requesting information on yearly number of cases, age group and sex for the period 2010 to 2014.
Among 150 neuroborreliosis cases, 67 (45%) had received the ICD-10 code A69.2 (Lyme borreliosis) in combination with G01.9 (meningitis in bacterial diseases classified elsewhere), the combination that the Swedish National Board of Health and Welfare recommends for neuroborreliosis. All 22 clinical laboratories replied to our questionnaire. Based on laboratory reporting, the annual incidence of neuroborreliosis in Sweden was 6.3 cases per 100,000 in 2014.
The hospital discharge register was unsuitable for surveillance of neuroborreliosis, whereas laboratory-based reporting was a feasible alternative. In 2018, the European Commission included Lyme neuroborreliosis on the list of diseases under epidemiological surveillance.
Meningitis - Neisseria -- Saudi Arabia
Specialespecifikt kursus om immundefekt og feber af ukendt årsag
28.01.2020 - 29.01.2020
International Congress on Infectious Diseases (ICID) 2020
Kuala Lumpur, Malaysia
20.02.2020 - 23.02.2020
Dansk Selskab for Intern Medicin (DSIM) årsmøde og overrækkelse af Hagedorn prisen 2020
Novo Nordisk Fonden, Tuborg Havnevej 19, 2900 Hellerup
Conference on Retroviruses and Opportunistic Infections (CROI) 2020
Boston, Massachusetts, USA
8.03.2020 - 11.03.2020
Når CROI går i fisk - med transmissioner fra CROI 2020
10.03.2020 - 11.03.2020
Retningslinjer til sundhedsprofessionelle vedr. håndtering af infektion med zikavirus (2019)
Antiviral behandling af hiv smittede personer (2019)
Lumbalpunktur af patienter i blodfortyndende behandling (2019)
How to Choose Target Facilities in a Region to Implement Carbapenem-Resistant Enterobacteriaceae (CRE) Control Measures
23.01.2020Clinical Infectious Diseases Advance Access
Evaluation of Genotypic Antiviral Resistance Testing as an Alternative to Phenotypic Testing in a Patient with DOCK8 Deficiency and Severe HSV-1 Disease
23.01.2020The Journal of Infectious Diseases Advance Access
Bronchiectasis;a progressive phenotype of Chronic Obstructive Pulmonary Disease
22.01.2020Clinical Infectious Diseases Advance Access
BRONCHIAL INFECTION AND temporal evolution OF bronchiectasis in patients with chronic obstructive pulmonary disease
22.01.2020Clinical Infectious Diseases Advance Access
More Screening or More Disease? Gonorrhea Testing and Positivity Patterns among Men in Three Large Clinical Practices in Massachusetts, 2010-2017
22.01.2020Clinical Infectious Diseases Advance Access
Hvorfor anbefaler Professor Jens Lundgren artiklen"Dolutegravir plus Two Different Prodrugs of Tenofovir to Treat HIV."?
Hvorfor anbefaler Professor Troels Lillebæk artiklen"The global prevalence of latent tuberculosis: a systematic review and meta-analysis."?
Hvad tænker Professor Lars Østergaard om"Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial."?
Hvad tænker Professor Thomas Benfield om"Oral versus Intravenous Antibiotics for Bone and Joint Infection."?
Hvad synes Professor Niels Obel om"Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis."?
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