Sidst opdateret 24.11.2018
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Enrico Ricchizzi, Katrien Latour, Tommi Kärki, Rossella Buttazzi, Béatrice Jans, Maria Luisa Moro, Olivia Aya Nakitanda, Diamantis Plachouras, Dominique L Monnet, Carl Suetens, Pete Kinross and the HALT Study Group
Antimicrobials are commonly prescribed and contribute to the development of antimicrobial resistance in long-term care facilities (LTCFs). In 2010, the European Centre for Disease Prevention and Control initiated point prevalence surveys (PPS) of healthcare-associated infections and antimicrobial use in European LTCFs, performed by external contractors as the Healthcare-Associated infections in Long-Term care facilities (HALT) projects. Here, we investigated prevalence and characteristics of antimicrobial use and antimicrobial stewardship indicators in European LTCFs in 2016–17. Twenty-four European Union/European Economic Area (EU/EEA) countries, the former Yugoslav Republic of Macedonia and Serbia participated in the third PPS in European LTCFs. Overall, 4.9% (95% confidence interval: 4.8–5.1) of LTCF residents in the EU/EEA participating countries received at least one antimicrobial. The most commonly reported Anatomical Therapeutic Chemical (ATC) groups were beta-lactam antibacterials/penicillins (J01C), other antibacterials (J01X) (e.g. glycopeptide antibacterials, polymyxins), quinolones (J01M), sulfonamides and trimethoprim (J01E), and other beta-lactams (J01D). Urinary tract infections and respiratory tract infections were the main indications for antimicrobial prescription. This PPS provides updated and detailed information on antimicrobial use in LTCFs across the EU/EEA that can be used to identify targets for future interventions, follow-up of these interventions and promote prudent use of antimicrobials in European LTCFs.
Sebastian Thole, Daniela Kalhoefer, Maria an der Heiden, Doris Nordmann, Inka Daniels-Haardt and Annette Jurke
When a person with contagious measles has travelled by aircraft, European guidelines recommend contact tracing of passengers and crew within 5 days of exposure for post-exposure prophylaxis (PEP), and within 12 days of exposure for informing passengers and crew, in order to prevent further transmissions. To be effective, contact tracing requires prompt diagnosis, immediate notification of public health authorities and rapid availability of passenger contact data. We report two events of contact tracing initiated in Germany after two individuals with measles travelled on three international flights. In one event, contact tracing was initiated late because laboratory confirmation of a clinically diagnosed measles case was awaited unnecessarily. Accessing passenger contact data was difficult in both events because of data protection issues with the airline which was not based in Germany. In both events, passengers were not reached in time to provide PEP, and one event resulted in at least two secondary measles cases. As all passengers were reached before the incubation period ended, tertiary cases were most probably prevented. Public health authorities and the transport sector must collaborate to resolve competing legal regulations for infection prevention and data protection, to simplify and accelerate identification of air travellers exposed to communicable diseases.
Chronic Wasting Disease -- United StatesThe Virginia Department of Game and Inland Fisheries (DGIF) has confirmed chronic wasting disease (CWD) in a male deer (buck) legally harvested in Culpeper county in November 2018.A cooperating taxidermist submitted the sample to DGIF in late January . At the time this deer was harvested, the hunter did not notice any outward signs of disease and the buck appeared to be in good condition.While CWD has been documented in northwest Virginia for over 9 years, this deer was harvested
Other Animal Disease -- RussiaThe crops that bring us most of our food provide for 35 per cent of calorie intake, as well as most minerals, vitamins, and antioxidants. Nuts, melons, and berries will not grow without pollinating insects. Bees also pollinate citrus fruits, apples, onions, broccoli cabbage, zucchini, beans, peppers, eggplants, cucumbers, tomatoes, beans, coffee, cocoa, avocados, and coconuts. The production of these crops belongs to most valuable segments of the global food industry. Thus, the disappearance
Rift Valley Fever -- Région d'outre-mer de Mayotte, France1. Ministry of Agriculture and Food, France. Presentation: Rift Valley fever (RVF) situation in Mayotte, a French department in the Indian Ocean. EU - Standing Committee on Plants, Animals, Food and Feed (SCPAFF), 21 Mar 2019 committee meeting; .2. Chevalier V, Pepin M, Plee L, Lancelot R. Rift Valley fever -- a threat for Europe? Euro Surveill. 2010; 15(10): pii=19506; .3. European Centre for Disease Prevention and Control. Rift Valley fever outbreak in Mayotte, France. Stockholm: ECDC;
Other Plant Disease -- United States_Impatiens necrotic spot virus_ (INSV) was confirmed by the [University of Massachusetts] on pepper [capsicum] seedlings grown in a greenhouse. Symptoms of INSV on pepper include leaf distortion and tan or brown lesions that may or may not be circular. Wilting and necrosis of meristems may also occur.Management starts with discarding infected plants. Monitor and manage thrips populations in the greenhouse. Carefully inspect all incoming plant material for disease symptoms and thrips.
-- United KingdomThe statement [in the source media report ProMED-mail post http://promedmail.org/post/20190523.6483054] that "The virus displays symptoms akin to _Tomato brown rugose fruit virus_ or _Pepino mosaic virus_" is inaccurate. STV [_Southern tomato virus_] was initially reported from symptomatic tomatoes in the US, but its link to the symptoms never proven. In several cases where it has been described since that initial report, it was in symptomless plants. As far as I know, there is to date no good
Retningslinjer til sundhedsprofessionelle vedr. håndtering af infektion med zikavirus (2019)
Antiviral behandling af hiv smittede personer (2019)
Lumbalpunktur af patienter i blodfortyndende behandling (2019)
Resistance of Influenza Virus to Antiviral Medications
20.09.2019Clinical Infectious Diseases Advance Access
Erratum to: Chlamydia trachomatis and the Risk of Pelvic Inflammatory Disease, Ectopic Pregnancy, and Female Infertility: A Retrospective Cohort Study Among Primary Care Patients
19.09.2019Clinical Infectious Diseases Advance Access
Comparison of repeated doses of ivermectin versus ivermectin plus albendazole for treatment of onchocerciasis – a randomized open-label clinical trial
19.09.2019Clinical Infectious Diseases Advance Access
Association between Toxoplasma gondii infection and thyroid dysfunction: a case-control seroprevalence study
18.09.2019Latest Results for BMC Infectious Diseases
Antimicrobial Stewardship in a Hematological Malignancy Unit: Carbapenem Reduction and Decreased Vancomycin-resistant Enterococcus Infection
18.09.2019Clinical Infectious Diseases Advance Access
Hvorfor anbefaler Professor Thomas Benfield artiklen"Oral versus Intravenous Antibiotics for Bone and Joint Infection."?
Hvad tænker Professor Niels Obel om"Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis."?
Hvorfor anbefaler Professor Thomas Benfield artiklen"Duration of Antibiotic Treatment in Community-Acquired Pneumonia: A Multicenter Randomized Clinical Trial."?
Hvad tænker Professor Morten Sodemann om"Evidence-based clinical guidelines for immigrants and refugees."?
Hvad synes Professor Niels Obel om"Use of statins and risk of AIDS-defining and non-AIDS-defining malignancies among HIV-1 infected patients on antiretroviral therapy."?
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