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More hospitals have personal protective equipment for front-line employees, he says, although many hospitals say they're still woefully short.
Although many users praised the results of the Recovery trial now in preprint, others want more definitive answers.
Thousands of coronavirus patients have survived the ICU. Now, a prepandemic research movement may help physicians figure out how to help them through what comes next.
COVID-19 -- DenmarkA herd of mink is being slaughtered at a farm in North Jutland after several of the animals and one employee tested positive for coronavirus. Nicholas Kuhn Hove, the head of emergency preparedness at the Danish Veterinary and Food Administration said in a press statement that samples from the animals had been sent to be tested at Denmark's infectious diseases agency (SSI; Statens Serum Institut) over the weekend [13-14 Jun 2020], after some of the animals displayed symptoms.At the same
COVID-19 -- Worldwide/Unknown- WHO has published a rapid advice guidance on the use of chest imaging in COVID-19. The guide examines available evidence and makes recommendations for the use of radiography, computed tomography and ultrasound for acute care of adult patients with suspected, probable or confirmed COVID-19 at different levels of disease severity.- The private sector plays a critical role in the preparedness and response activities for COVID-19 locally, nationally and globally. WHO has published 'Asks' to
Max Augustin, Philipp Schommers, Isabelle Suárez, Philipp Koehler, Henning Gruell, Florian Klein, Christian Maurer, Petra Langerbeins, Vanessa Priesner, Kirsten Schmidt-Hellerau, Jakob J Malin, Melanie Stecher, Norma Jung, Gerhard Wiesmüller, Arne Meissner, Janine Zweigner, Georg Langebartels, Felix Kolibay, Victor Suárez, Volker Burst, Philippe Valentin, Dirk Schedler, Oliver A Cornely, Michael Hallek, Gerd Fätkenheuer, Jan Rybniker and Clara Lehmann
The coronavirus disease (COVID-19) pandemic has caused tremendous pressure on hospital infrastructures such as emergency rooms (ER) and outpatient departments. To avoid malfunctioning of critical services because of large numbers of potentially infected patients seeking consultation, we established a COVID-19 rapid response infrastructure (CRRI), which instantly restored ER functionality. The CRRI was also used for testing of hospital personnel, provided epidemiological data and was a highly effective response to increasing numbers of suspected COVID-19 cases.
This report describes gaps in knowledge about safe preparation, use, and storage of cleaners and disinfectants identified by an internet panel survey.
WHO har 1/12-2017 i en rapport fra Strategic Advisory Group of Experts on Immunization, SAGE, udgivet nye retningslinjer på baggrund af ny evidens om brugen af rabiesvacciner og rabies-immunglobulin (RIG).
COVID-19 -- Worldwide/UnknownReference: Angela M. Bosco-Lauth, Airn E. Hartwig, Stephanie M. Porter, Paul W. Gordy et al. Pathogenesis, transmission and response to re-exposure of SARS-CoV-2 in domestic cats. bioRxiv preprint doi: [this version posted 29 May 2020].AbstractThe pandemic caused by SARS-CoV-2 has reached nearly every country in the world with extraordinary person-to-person transmission. The most likely original source of the virus was spillover from an animal reservoir and subsequent adaptation to
Marino Faccini, Antonio Giampiero Russo, Maira Bonini, Sara Tunesi, Rossella Murtas, Monica Sandrini, Sabrina Senatore, Anna Lamberti, Giorgio Ciconali, Serafina Cammarata, Eros Barrese, Valentina Ceriotti, Sonia Vitaliti, Marina Foti, Gabriella Gentili, Elisabetta Graziano, Emerico Panciroli, Marco Bosio, Maria Gramegna, Danilo Cereda, Carlo Federico Perno, Ester Mazzola, Daniela Campisi, Gianuario Aulicino, Silvana Castaldi, Antonietta Girolamo, Maria Grazia Caporali, Maria Scaturro, Maria Cristina Rota a
In July 2018, a large outbreak of Legionnaires’ disease (LD) caused by Legionella pneumophila serogroup 1 (Lp1) occurred in Bresso, Italy. Fifty-two cases were diagnosed, including five deaths. We performed an epidemiological investigation and prepared a map of the places cases visited during the incubation period. All sites identified as potential sources were investigated and sampled. Association between heavy rainfall and LD cases was evaluated in a case-crossover study. We also performed a case–control study and an aerosol dispersion investigation model. Lp1 was isolated from 22 of 598 analysed water samples; four clinical isolates were typed using monoclonal antibodies and sequence-based typing. Four Lp1 human strains were ST23, of which two were Philadelphia and two were France-Allentown subgroup. Lp1 ST23 France-Allentown was isolated only from a public fountain. In the case-crossover study, extreme precipitation 5–6 days before symptom onset was associated with increased LD risk. The aerosol dispersion model showed that the fountain matched the case distribution best. The case–control study demonstrated a significant eightfold increase in risk for cases residing near the public fountain. The three studies and the matching of clinical and environmental Lp1 strains identified the fountain as the source responsible for the epidemic.
African Swine Fever -- IndiaIn the wake of the African swine fever (ASF) killing nearly 15 000 pigs in Assam and spreading to new areas despite preventive measures, the state government is preparing to go for mass culling, according to media reports.Earlier this month [May 2020], Assam Animal Husbandry and Veterinary Minister Atul Bora had said that the Centre has advised the state government to go for the culling of pigs affected by ASF.The disease was first reported in November-December 2019 from areas of China
Facing the daily rigors of treating patients with COVID-19, seven clinicians share how they prepare themselves for something they trained for but never quite expected.
These are the coronavirus stories you need to know about today.
Malaria -- YemenDoctors Without Borders (MSF) yesterday [27 Apr 2020] warned of an "increasing risk of malaria outbreak in Yemen," as rain floods the country. "With the start of the rain season, a risk of a malaria outbreak in Yemen increases," MSF said on Twitter, on the occasion of the World Malaria Day [25 Apr 2020]."While Yemen is currently preparing for a possible spread of COVID-19 the rest of the health system needs to be kept running, or else we must expect a rise in deaths from other diseases
Measles -- Worldwide/UnknownStory Highlights- A statement from the Measles & Rubella Initiative indicates that the COVID-19 pandemic could cause dozens of measles immunization campaigns worldwide to be postponed or suspended.- The initiative estimates that more than 117 million children could be at risk of missing their measles vaccinations as a result.- To address member concerns, the AAFP has developed resources on office preparedness and preventive and nonurgent care, including immunizations.As the numbers
Valerija Tkalec, Urska Jamnikar-Ciglenecki, Maja Rupnik, Stanka Vadnjal, Katja Zelenik and Majda Biasizzo
Clostridioides difficile is an important human and animal intestinal pathogen. Because of increasing indications of an association between C. difficile and food, in 2015, the Administration of the Republic of Slovenia for Food Safety, Veterinary Sector and Plant Protection (UVHVVR) included C. difficile in its national food surveillance.
We aim to report the results and experience with a nationwide and long-term testing of food for C. difficile as a part of a regular national food surveillance programme.
Retail minced meat and meat preparations (beef, pork and poultry) were sampled within a three-year period, 2015 to 2017. Selected raw retail vegetables, leaf salads and root vegetables, and ready-to-eat salads were only sampled during 2016 and 2017. Seafood was only sampled in 2017.
Altogether, 434 samples were tested, with 12 of 336 (3.6%) meat samples and 6 of 98 (6.1%) raw vegetables contaminated with C. difficile. Twelve of 18 recovered food isolates were toxigenic (toxinotypes 0, III, V, XII). The isolates belonged to 13 different PCR ribotypes, 001 being most common (5 isolates). Several food types with an increased potential of being contaminated with C. difficile were detected by surveillance.
The three-year C. difficile testing within the national food surveillance revealed a low proportion of C. difficile-contaminated food and high genotype variability. Because the risk of C. difficile infection associated with C. difficile-contaminated food is unknown, no measures were recommended in the case of positive results.
These are the coronavirus stories you need to know about today.
Although triage of critical care resources should be a rare event during the COVID-19 crisis, failing to prepare for the worst-case scenario could have serious consequences.
A preprint based on 'influenza-like illness' models a U.S. incidence in the millions
Meng Lv, Xufei Luo, Janne Estill, Yunlan Liu, Mengjuan Ren, Jianjian Wang, Qi Wang, Siya Zhao, Xiaohui Wang, Shu Yang, Xixi Feng, Weiguo Li, Enmei Liu, Xianzhuo Zhang, Ling Wang, Qi Zhou, Wenbo Meng, Xiaolong Qi, Yangqin Xun, Xuan Yu, Yaolong Chen and on behalf of the COVID-19 evidence and recommendations working group
In December 2019, a pneumonia caused by a novel coronavirus (SARS-CoV-2) emerged in Wuhan, China and has rapidly spread around the world since then.
This study aims to understand the research gaps related to COVID-19 and propose recommendations for future research.
We undertook a scoping review of COVID-19, comprehensively searching databases and other sources to identify literature on COVID-19 between 1 December 2019 and 6 February 2020. We analysed the sources, publication date, type and topic of the retrieved articles/studies.
We included 249 articles in this scoping review. More than half (59.0%) were conducted in China. Guidance/guidelines and consensuses statements (n = 56; 22.5%) were the most common. Most (n = 192; 77.1%) articles were published in peer-reviewed journals, 35 (14.1%) on preprint servers and 22 (8.8%) posted online. Ten genetic studies (4.0%) focused on the origin of SARS-CoV-2 while the topics of molecular studies varied. Nine of 22 epidemiological studies focused on estimating the basic reproduction number of COVID-19 infection (R0). Of all identified guidance/guidelines (n = 35), only ten fulfilled the strict principles of evidence-based practice. The number of articles published per day increased rapidly until the end of January.
The number of articles on COVID-19 steadily increased before 6 February 2020. However, they lack diversity and are almost non-existent in some study fields, such as clinical research. The findings suggest that evidence for the development of clinical practice guidelines and public health policies will be improved when more results from clinical research becomes available.
An academic infectious diseases physician shares her reflections as she prepares to join the frontlines in the COVID-19 battle.
Prepare for tick season by reviewing these five things to know about Lyme disease testing.
Not Yet Classified -- Worldwide/UnknownLi Wenliang, a face to the frontline healthcare worker. The first doctor to notify the emergence of the SARS-CoV-2, (COVID-19), outbreak.Eskild Petersen, David Hui, Davidson H Hamer, Lucille Blumberg, Lawrence C Madoff, Marjorie Pollack, et al.Int J Infect Dis. 2020; 93(Apr): 205-207.Is Africa prepared for tackling the COVID-19 (SARS-CoV-2) epidemic. Lessons from past outbreaks, ongoing pan-African public health efforts, and implications for the future.Nathan Kapata, Chikwe
Giulietta Venturi, Stephan W Aberle, Tatjana Avšič-Županc, Luisa Barzon, Christoph Batejat, Elisa Burdino, Fabrizio Carletti, Rémi Charrel, Iva Christova, Jeff Connell, Victor Max Corman, Mary Emmanouil, Anne J Jääskeläinen, Ivan Kurolt, Yaniv Lustig, Miguel J Martinez, Marion Koopmans, Orsolya Nagy, Trung Nguyen, Anna Papa, Mercedes Pérez-Ruiz, Martin Pfeffer, Jelena Protic, Johan Reimerink, Giada Rossini, María Paz Sánchez-Seco Fariñas, Jonas Schmidt-Chanasit, Sandra Söderholm, Bertrand Sudre, Marjan Van
We illustrate the potential for specialist laboratory networks to be used as preparedness and response tool through rapid collection and sharing of data. Here, the Emerging Viral Diseases-Expert Laboratory Network (EVD-LabNet) and a laboratory assessment of chikungunya virus (CHIKV) in returning European travellers related to an ongoing outbreak in Thailand was used for this purpose. EVD-LabNet rapidly collected data on laboratory requests, diagnosed CHIKV imported cases and sequences generated, and shared among its members and with the European Centre for Disease Prevention and Control. Data across the network showed an increase in CHIKV imported cases during 1 October 2018–30 April 2019 vs the same period in 2018 (172 vs 50), particularly an increase in cases known to be related to travel to Thailand (72 vs 1). Moreover, EVD-LabNet showed that strains were imported from Thailand that cluster with strains of the ECSA-IOL E1 A226 variant emerging in Pakistan in 2016 and involved in the 2017 outbreaks in Italy. CHIKV diagnostic requests increased by 23.6% between the two periods. The impact of using EVD-LabNet or similar networks as preparedness and response tool could be improved by standardisation of the collection, quality and mining of data in routine laboratory management systems.
With all the preparations, it was hoped that Paris would be at the optimistic end of predictions for the COVID-19 epidemic, but as the weeks pass, it looks more and more like a catastrophe is coming.
Hospitals throughout the country are preparing for an influx of patients with the novel coronavirus. But their finances may not be able to take the hit, prompting a rash of furloughs and pay cuts.
A physician leader and a health workforce expert offer recommendations in preparing for an expected rise in COVID-19 cases. Knowledge about local trends in infection rates is key to preparedness.
Diamantis Plachouras, Felix Lötsch, Anke Kohlenberg, Dominique L Monnet and the Candida auris survey collaborative group
Between January 2018 and May 2019, 349 cases of Candida auris were reported in the European Union/European Economic Area*, 257 (73.6%) colonisations, 84 (24.1%) bloodstream infections, seven (2.0%) other infections and one case of unknown infection/colonisation status (0.3%). Most cases (97.1%, n = 339) were reported from Spain or the United Kingdom, but also for the first time in Greece, the Netherlands and Poland. Laboratory capacity and preparedness has improved since January 2018.
Kristin Tolksdorf, Silke Buda, Ekkehard Schuler, Lothar H Wieler and Walter Haas
Information on severity of coronavirus disease (COVID-19) (transmissibility, disease seriousness, impact) is crucial for preparation of healthcare sectors. We present a simple approach to assess disease seriousness, creating a reference cohort of pneumonia patients from sentinel hospitals. First comparisons exposed a higher rate of COVID-19 patients requiring ventilation. There were more case fatalities among COVID-19 patients without comorbidities than in the reference cohort. Hospitals should prepare for high utilisation of ventilation and intensive care resources.
Pete Kinross, Carl Suetens, Joana Gomes Dias, Leonidas Alexakis, Ariana Wijermans, Edoardo Colzani, Dominique L. Monnet and European Centre for Disease Prevention and Control (ECDC) Public Health Emergency Team
The cumulative incidence of coronavirus disease (COVID-19) cases is showing similar trends in European Union/European Economic Area countries and the United Kingdom confirming that, while at a different stage depending on the country, the COVID-19 pandemic is progressing rapidly in all countries. Based on the experience from Italy, countries, hospitals and intensive care units should increase their preparedness for a surge of patients with COVID-19 who will require healthcare, and in particular intensive care.
University of Washington's internal medicine clinic has faced a steady stream of patients concerned they may have COVID-19. What has the clinic learned that can help others prepare for the onslaught?
A psychiatrist gives her advice on what psychiatrists and other clinicians can do to mitigate the psychological consequences of COVID-19.
Helen C Johnson, Céline M Gossner, Edoardo Colzani, John Kinsman, Leonidas Alexakis, Julien Beauté, Andrea Würz, Svetla Tsolova, Nick Bundle and Karl Ekdahl
Two months after the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the possibility of established and widespread community transmission in the European Union and European Economic Area (EU/EEA) is becoming more likely. We provide scenarios for use in preparedness for a possible widespread epidemic. The EU/EEA is moving towards the ‘limited sustained transmission’ phase. We propose actions to prepare for potential mitigation phases and coordinate efforts to protect the health of citizens.
When taken daily, preexposure prophylaxis (PrEP) reduces the risk of acquiring human immunodeficiency virus (HIV). PrEP is an important tool for preventing HIV among persons at substantial risk for HIV infection, including female sex workers, men who have sex with men, transgender women, and persons who inject drugs.
Clinicians can help lead the way in COVID-19 preparedness by fighting pandemic denial in themselves and being frank with their patients, an expert in risk communication said.
It's past time to call the novel coronavirus, COVID-19, a pandemic and help people prepare for widespread cases, experts said.
With 34 confirmed cases of the virus in the US now, the CDC is preparing for potential community spread of 2019-nCoV in the US and is not ruling out the future need for school and business closures.
COVID-19 -- Worldwide/Unknown[The document includes a brief description of the event as known at the time of its finalization. In response to the described outbreak, the WSAVA Scientific and One Health Committees have prepared the following list of frequently asked questions for the WSAVA membership with the help of Prof. Scott Weese from the University of Guelph, Canada, "while being aware of issues related to pet abandonment in China and hope that this information will be of use to veterinarians in dealing with the
What should every clinic do to prepare for patients with potential Wuhan coronavirus (2019-nCoV) infection? Here are the answers to clinicians' frequently asked questions.
With the arrival of the new coronavirus, 2019-nCoV, there is much to learn. What do we know about it already, and how can we prepare for its possible spread?
MERS -- Saudi ArabiaIn the 2 days since the last update was prepared (see MERS-CoV (03): Saudi Arabia (AS,RI) RFI http://promedmail.org/post/20200124.6911579), there have been 3 additional newly confirmed cases posted on the Saudi MOH website. No outcomes were reported.Information on newly confirmed cases:Date of confirmation report: 22 Jan 2020Case No. 20-1989A 36-year-old female in Abha city, Aseer (Asir) regionContact with camels: noCase classification: secondaryHealthcare worker:
This summer's record-breaking outbreak of Eastern equine encephalitis highlights the importance of cities and states ability to prepare for and respond to vectorborne disease threats.
Timely state- or local-level estimates of the number of persons who are ill and seek medical care due to influenza (flu) contribute to preparedness and communication messages needed during flu season and in the event of a flu pandemic.
Polio -- PakistanNew wild poliovirus isolates reported this week:AFP cases: 3Environment: 9Others: 0New cVDPV isolates reported this week:AFP cases: 22Environment: 11Others: 4Headlines- In the run up to the WPV certification of the African region next year , the Africa Regional Certification Commission is currently conducting a visit in Nigeria to analyze and verify the accuracy of the certification documents prepared by the Nigerian government. "It is important that the Nigerian
Salmonella -- United StatesFood service and institutional food operators should not sell or serve the fruit mix with cantaloupe, honeydew, pineapple, and grapes prepared by Tailor Cut Produce.Tailor Cut Produce reports that their products may be found in restaurants, banquet facilities, hotels, schools and institutional food service establishments in New Jersey, New York, and Pennsylvania.Because this fruit mix may have been distributed to nursing homes, schools, hospitals and other facilities that cater to
Foot and Mouth -- South AfricaThe FMD [foot and mouth disease] outbreaks have caused the country to lose its FMD-free status, meaning South African farmers cannot export animals or animal products. This significantly impacts our economy. To local consumers, the FMD outbreak means meat prices, especially red meat, will likely increase. As consumers prepare for the festive season, expect meat prices to be high as markets struggle to find animals for meat. Provinces that are already banned from selling their animals in
Charlotte O’Halloran, Greg Owen, Sara Croxford, Lee B Sims, O Noel Gill, Will Nutland and Valerie Delpech
The 2019 online pre-exposure prophylaxis (PrEP) user survey in the United Kingdom was conducted to assess HIV PrEP access, and user characteristics. One in five respondents continued experiencing difficulties accessing PrEP; users were almost exclusively gay or bisexual men at high risk of HIV. The majority obtained PrEP through health service clinics and rated PrEP positively. High STI rates were reported among users. Renal and sexual health checks are advised for those sourcing PrEP privately.
Salmonella -- ChileA salmonellosis outbreak in Maipu commune in Santiago Province has now affected 80 people, according to the Chile news source, T13 (computer translated). This is up from 45 cases reported ill at the El Carmen Hospital with symptoms of salmonella infection on [Tue 19 Nov 2019].Health officials have linked to outbreak to the consumption of sushi at a Bokado sushi store. "This is an important call for the preparation of these products, they must be cooked. They must not use salmon or raw
Prevention efforts need to increase PrEP use among all MSM and target eliminating racial/ethnic disparities in PrEP use.
International AIDS Conference (AIDS) 2020
6.07.2020 - 10.07.2020
International Liver Congress (ILC) 2020
27.08.2020 - 29.08.2020
World Sepsis Day
Det 8. videnskabelige nationale møde om infektiøs endokarditis
International Congress for Tropical Medicine and Malaria (ICTMM) 2020
20.09.2020 - 24.09.2020
COVID-19 retningslinje (2020)
National handlingsplan for antibiotika til mennesker (2017)
Retningslinjer til sundhedsprofessionelle vedr. håndtering af infektion med zikavirus (2019)
Infections in Patients Colonized with Extended-Spectrum Beta-Lactamase-Producing Enterobacterales – a Retrospective Cohort Study
30.07.2020Clinical Infectious Diseases Advance Access
Lopinavir/ritonavir is associated with pneumonia resolution in COVID‐19 patients with influenza coinfection: a retrospective matched‐pair cohort study
4.07.2020Wiley: Journal of Medical Virology: Table of Contents
Establishment of a rapid ELISPOT assay for influenza virus titration and neutralizing antibody detection
4.07.2020Wiley: Journal of Medical Virology: Table of Contents
Deep throat saliva as an alternative diagnostic specimen type for the detection of SARS‐CoV‐2
4.07.2020Wiley: Journal of Medical Virology: Table of Contents
Zoonoses: beyond the human–animal–environment interface
Hvad mener Professor Jens Lundgren om artiklen"Dolutegravir plus Two Different Prodrugs of Tenofovir to Treat HIV."?
Hvad mener Professor Troels Lillebæk om artiklen"The global prevalence of latent tuberculosis: a systematic review and meta-analysis."?
Hvad tænker Professor Lars Østergaard om"Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial."?
Hvad tænker Professor Thomas Benfield om"Oral versus Intravenous Antibiotics for Bone and Joint Infection."?
Hvad mener Professor Niels Obel om artiklen"Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis."?
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