Sidst opdateret 08.01.2020
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Søgeord (sepsis) valgt. Opdateret for 9 timer siden.11 emner vises.
A rapid blood assay accurately classifies risk according to severity and suggests higher-dose antibiotics should be an early option for patients with severe sepsis whose outlook is poor, new data show.
Whole genome sequencing indicated a potential common source of bacterial contamination among four cases of septic transfusion reactions occurring in three states.
Staphylococcus aureus is a major cause of community- and health care-associated infections, ranging from superficial skin and soft tissue infections (SSTI) to invasive infections, sepsis, and death. Methicillin-resistant S. aureus (MRSA) has long been recognized as a pathogen associated with health care settings; however, in the 1990s, community-associated MRSA infections, causing mostly SSTI, emerged in the United States.
Three medical stories that we didn't cover, explained.
Adriana Cabal, Franz Allerberger, Steliana Huhulescu, Christian Kornschober, Burkhard Springer, Claudia Schlagenhaufen, Marianne Wassermann-Neuhold, Harald Fötschl, Peter Pless, Robert Krause, Anna Lennkh, Andrea Murer, Werner Ruppitsch and Ariane Pietzka
In late December 2018, an outbreak of listeriosis occurred after a group of 32 individuals celebrated in a tavern in Styria, Austria; traditional Austrian food (e.g. meat, meat products and cheese) was served. After the celebration, 11 individuals developed gastrointestinal symptoms, including one case with severe sepsis. Cases had consumed mixed platters with several meat products and pâtés originating from a local production facility (company X). Human, food and environmental samples taken from the tavern and company X were tested for L. monocytogenes. Whole genome sequence-based typing detected a novel L. monocytogenes strain of serotype IVb, sequence type 4 and CT7652 in 15 samples; 12 human, two food and one environmental sample from company X with an allelic difference of 0 to 1. Active case finding identified two further cases who had not visited the tavern but tested positive for the outbreak strain. In total, 13 cases (seven females and six males; age range: 4–84 years) were identified. Liver pâté produced by company X was identified as the likely source of the outbreak. Control measures were implemented and since the end of December 2018, no more cases were detected.
An effective intervention for severe sepsis and septic shock can't come soon enough.
Staph -- United StatesA total of 4 people in 3 states developed sepsis after receiving bacteria-contaminated platelet transfusions between May and October last year , according to a US government report released Thursday [13 Jun 2019]. One of the 4 patients died.The source of the bacterial contamination of the platelets isn't clear. An analysis by the Centers for Disease Control and Prevention [CDC] found that the bacteria were closely related, and the contamination might be from a common source. An
Zaida Herrador, Alin Gherasim, Rogelio López-Vélez and Agustín Benito
Listeriosis is a food-borne disease of public health importance that has recently been involved in prolonged outbreaks. Despite its relevance, listeriosis is under-reported in many European countries.
We aimed to describe listeriosis epidemiology in Spain from 1997–2015.
We performed a retrospective study using the Spanish hospitalisation database. We calculated the mean number of hospitalisations per year and region. Pregnancy and neonatal-related listeriosis rates were computed. Relation between death and the presence of underlying health conditions was explored.
Between 1997–2015, 5,696 listeriosis hospitalisations occurred, showing a constantly increasing trend. Higher hospitalisation rates were located in the north of the country compared to southern regions. The age group ≥ 65 years old was the most represented (50%). Pregnant women and newborns accounted for 7% and 4% of hospitalisations, respectively. An underlying immunocompromising condition was present in 56.4% of patients: cancer (22.8%), diabetes mellitus (16.6%) and chronic liver disease (13.1%). Death occurred in 17% of patients, more frequently among those ≥ 65 years old (67.5%), with sepsis (39.9%) or with meningoencephalitis (19.2%).
Listeriosis is an emergent public health problem in Spain that calls for targeted action. Further prevention strategies are urgently needed, including food safety education and messaging for all at-risk groups.
Guidelines to prevent antibiotic overuse have cut prescribing by 13% in the UK but may be putting older patients with UTIs at risk for bloodstream infections and death.
Sepsis -- China"_Enterobacter_ strains 090008T and 090028T were recovered from the blood of 2 different patients at West China Hospital, Chengdu, PR China in 2017. Phylogenetic analysis based on the 16S rRNA gene and multi-locus sequence analysis of the rpoB, gyrB, infB and atpD housekeeping genes revealed that the 2 strains were distinct from any previously known species of the genus _Enterobacter_. Both average nucleotide identity (ANI) and in silico DNA-DNA hybridization (isDDH) values between strains
International Liver Congress (ILC) 2020
15.04.2020 - 19.04.2020
European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 2020
18.04.2020 - 21.04.2020
DSI årsmøde 2020 (aflyst)
Hindsgavl Slot, Middelfart
1.05.2020 - 2.05.2020
Kursus i rejsemedicin 2020
Statens Serum Institut
4.05.2020 - 6.05.2020
5.05.2020 - 7.05.2020
COVID-19 retningslinje (2020)
National handlingsplan for antibiotika til mennesker (2017)
Retningslinjer til sundhedsprofessionelle vedr. håndtering af infektion med zikavirus (2019)
Antiviral behandling af hiv smittede personer (2019)
Open versus endovascular repair of aortic aneurysms
COVID-19 will not leave behind refugees and migrants
Redefining vulnerability in the era of COVID-19
The COVID-19 pandemic in the USA: what might we expect?
A planetary health perspective on COVID-19: a call for papers
Hvad mener Professor Jens Lundgren om artiklen"Dolutegravir plus Two Different Prodrugs of Tenofovir to Treat HIV."?
Hvad synes Professor Troels Lillebæk om"The global prevalence of latent tuberculosis: a systematic review and meta-analysis."?
Hvorfor anbefaler Professor Lars Østergaard artiklen"Efficacy of antibiotic treatment in patients with chronic low back pain and Modic changes (the AIM study): double blind, randomised, placebo controlled, multicentre trial."?
Hvorfor synes Professor Thomas Benfield, at du bør læse"Oral versus Intravenous Antibiotics for Bone and Joint Infection."?
Hvad mener Professor Niels Obel om artiklen"Early, Goal-Directed Therapy for Septic Shock - A Patient-Level Meta-Analysis."?
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