Søgeord (pneumoni) valgt.
5 emner vises.
1
Emergence of OXA-48-producing Klebsiella pneumoniae in Lithuania, 2023: a multi-cluster, multi-hospital outbreak
Paulius Greičius, Marius Linkevicius, Jelena Razmuk, Jekaterina Sinotova, Erik Alm, Olov Svartström, Valeria Bortolaia, Eglė Kudirkienė, Louise Roer, Rene S Hendriksen, Gabija Tamoliūnaitė, Daniel Palm, Dominique L Monnet, Anke Kohlenberg and Algirdas Griškevičius
Eurosurveillance latest updates, 19.04.2024
Tilføjet 19.04.2024
In 2023, an increase of OXA-48-producing Klebsiella pneumoniae was noticed by the Lithuanian National Public Health Surveillance Laboratory. Whole genome sequencing (WGS) of 106 OXA-48-producing K. pneumoniae isolates revealed three distinct clusters of carbapenemase-producing K. pneumoniae high-risk clones, including sequence type (ST) 45 (n = 35 isolates), ST392 (n = 32) and ST395 (n = 28), involving six, six and nine hospitals in different regions, respectively. These results enabled targeted investigation and control, and underscore the value of national WGS-based surveillance for antimicrobial resistance.
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2
Emergence of OXA-48-like producing Citrobacter species, Germany, 2011 to 2022
Julian Sommer, Hannah Reiter, Janko Sattler, Elisabetta Cacace, Jessica Eisfeld, Sören Gatermann, Axel Hamprecht and Stephan Göttig
Eurosurveillance latest updates, 12.04.2024
Tilføjet 12.04.2024
BackgroundCarbapenemase-producing Enterobacterales are a public health threat worldwide and OXA-48 is the most prevalent carbapenemase in Germany and western Europe. However, the molecular epidemiology of OXA-48 in species other than Escherichia coli and Klebsiella pneumoniae remains poorly understood. AimTo analyse the molecular epidemiology of OXA-48 and OXA-48-like carbapenemases in Citrobacter species (spp.) in Germany between 2011 and 2022. MethodsData of 26,822 Enterobacterales isolates sent to the National Reference Centre (NRC) for Gram-negative bacteria were evaluated. Ninety-one Citrobacter isolates from 40 German hospitals harbouring blaOXA-48/OXA-48‑like were analysed by whole genome sequencing and conjugation experiments. ResultsThe frequency of OXA-48 in Citrobacter freundii (CF) has increased steadily since 2011 and is now the most prevalent carbapenemase in this species in Germany. Among 91 in-depth analysed Citrobacter spp. isolates, CF (n = 73) and C. koseri (n = 8) were the most common species and OXA-48 was the most common variant (n = 77), followed by OXA-162 (n = 11) and OXA‑181 (n = 3). Forty percent of the isolates belonged to only two sequence types (ST19 and ST22), while most other STs were singletons. The plasmids harbouring blaOXA‑48 and blaOXA-162 belonged to the plasmid types IncL (n = 85) or IncF (n = 3), and plasmids harbouring blaOXA‑181 to IncX3 (n = 3). Three IncL plasmid clusters (57/85 IncL plasmids) were identified, which were highly transferable in contrast to sporadic plasmids. ConclusionIn CF in Germany, OXA-48 is the predominant carbapenemase. Dissemination is likely due to distinct highly transmissible plasmids harbouring blaOXA‑48 or blaOXA-48-like and the spread of the high-risk clonal lineages ST19 and ST22.
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3
Ongoing measles outbreak, the Federation of Bosnia and Herzegovina, December 2023 to February 2024
Sanjin Musa, Irma Salimović-Bešić, Jasmina Brkić Džambić, Nijaz Tihić, Anisa Bajramović, Suzana Arapčić, Amela Dedeić-Ljubović and Siniša Skočibušić
Eurosurveillance latest updates, 1.03.2024
Tilføjet 1.03.2024
We report on an ongoing measles outbreak in the Federation of Bosnia and Herzegovina with 141 cases notified between week 52 2023 and week 6 2024. Among those with known vaccination status, 97% were unvaccinated and the most affected group is children under the age of 5 years (n = 87) who were not vaccinated during the pandemic years. Sixty-eight cases were hospitalised, the most common complications were measles-related pneumonia and diarrhoea. The sequenced measles viruses from four cases belonged to genotype D8.
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4
Notes from the Field: Reemergence of Mycoplasma pneumoniae Infections in Children and Adolescents After the COVID-19 Pandemic, United States, 2018-2024
Morbidity and Mortality Weekly Report (MMWR), 22.02.2024
Tilføjet 22.02.2024
This report describes an increase in Mycoplasma pneumoniae, a common cause of respiratory illness, beginning in fall 2023.
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5
Hypervirulent Resistant K pneumoniae On the Rise in EU
Medscape Infectious Diseases, 15.02.2024
Tilføjet 15.02.2024
The ECDC has called for mitigating actions in the face of more European Union and European Economic Area countries reporting hypervirulent Klebsiella pneumoniae ST23. Medscape Medical News
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