47 ud af 47 tidsskrifter valgt, søgeord (dengue) valgt, emner højest 180 dage gamle, sorteret efter nyeste først.
60 emner vises.
51
Advances and challenges in synthetic biology for mosquito control
Shih-Che Weng, Reem A. Masri, Omar S. Akbari
Trends in Parasitology, 24.11.2023
Tilføjet 24.11.2023
Mosquito-borne illnesses represent a significant global health peril, resulting in approximately one million fatalities annually. West Nile, dengue, Zika, and malaria are continuously expanding their global reach, driven by factors that escalate mosquito populations and pathogen transmission. Innovative control measures are imperative to combat these catastrophic ailments. Conventional approaches, such as eliminating breeding sites and using insecticides, have been helpful, but they face challenges such as insecticide resistance and environmental harm. Given the mounting severity of mosquito-borne diseases, there is promise in exploring innovative approaches using synthetic biology to bolster mosquitoes\' resistance to pathogens, or even eliminate the mosquito vectors, as a means of control. This review outlines current strategies, future goals, and the importance of gene editing for global health defenses against mosquito-borne diseases.
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52
Lambda-free light chain: A serum marker of dengue disease via NS3 protease-mediated antibody cleavage
Sheng-Hsuan WangBai-Jiun KuoTzu-Chuan HoShu-Wen WanKo-Lun YenPo-Hui HuangOscar Guey Chuen PerngPo-Lin ChenYu-Wen ChienYu-Chih Loa Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwanb Department of Biotechnology and Bioindustry Sciences, College of Bioscience and Biotechnology, National Cheng Kung University, Tainan, Taiwanc Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwand Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan, Taiwane Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwanf Center for Infection Control, National Cheng Kung University Medical College and Hospital, Tainan, Taiwang Department of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwanh Department of Occupational and Environmental Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
Virulence, 21.11.2023
Tilføjet 21.11.2023
53
Dispatch - Autochthonous Dengue Outbreak, Paris Region, France, September-October 2023
Emerging Infectious Diseases, 18.11.2023
Tilføjet 18.11.2023
Dispatch - Autochthonous Dengue Outbreak, Paris Region, France, September-October 2023
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54
Correction: Demographic and Clinico-Epidemiological Features of Dengue Fever in Faisalabad, Pakistan
Eun Jeong Yu, Eun-A. Park, Seung-Ah Choe, Kyung-Ah Lee, You Shin Kim
PLoS One Infectious Diseases, 8.11.2023
Tilføjet 8.11.2023
55
Correction: Increasing prevalence of malaria and acute dengue virus coinfection in Africa: a meta-analysis and meta-regression of cross-sectional studies
Malaria Journal, 4.11.2023
Tilføjet 4.11.2023
56
Virus infection participates in the occurrence and development of human diseases through monoamine oxidase
Yujie Sun; Wen Liu; Bing Luo;
Reviews in Medical Virology, 8.09.2023
Tilføjet 8.09.2023
Monoamine oxidase (MAO) is a membrane‐bound mitochondrial enzyme that maintains the steady state of neurotransmitters and other biogenic amines in biological systems through catalytic oxidation and deamination. MAO dysfunction is closely related to human neurological and psychiatric diseases and cancers. However, little is known about the relationship between MAO and viral infections in humans. This review summarises current research on how viral infections participate in the occurrence and development of human diseases through MAO. The viruses discussed in this review include hepatitis C virus, dengue virus, severe acute respiratory syndrome coronavirus 2, human immunodeficiency virus, Japanese encephalitis virus, Epstein‐Barr virus, and human papillomavirus. This review also describes the effects of MAO inhibitors such as phenelzine, clorgyline, selegiline, M‐30, and isatin on viral infectious diseases. This information will not only help us to better understand the role of MAO in the pathogenesis of viruses but will also provide new insights into the treatment and diagnosis of these viral diseases.
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57
Serum ferritin level as a prognostic biomarker for predicting dengue disease severity: A systematic review and meta‐analysis
Shridhar Shukla; Santosh M. Jadhav; Yogesh K. Gurav; Deepti Parashar; Kalichamy Alagarasu;
Reviews in Medical Virology, 8.09.2023
Tilføjet 8.09.2023
Serum ferritin levels serves as biomarkers in many inflammatory and infectious diseases. This current systematic review and meta‐analysis evaluated whether serum ferritin levels are associated with severe dengue and its utility as a biomarker of disease severity. Literature searches were conducted in PubMed, Scopus, ScienceDirect, the Cochrane library, and Google Scholar. A total of 18 studies examining the serum ferritin levels in dengue cases in the context of disease severity (nine studies having dengue classification as non‐severe vs. severe dengue cases, and nine studies having dengue classification as dengue without warning signs (DwoWS), dengue with warning signs (DwWS), and severe dengue cases) were included and the quality of the studies was assessed using the Quality in Prognostic Factor Studies tool. The meta‐analysis was performed using STATA software to calculate the effect size as a standardized mean difference (SMD) or Hedges ‘g’ for the continuous outcome. Higher serum ferritin levels were found in severe dengue cases compared to non‐severe cases [SMD (Hedges ‘g’) 4.05 (95% C.I. 2.09–6.00), ( = 98.8%)]. In the second group, DwWS cases showed high serum ferritin levels compared to DwoWS [SMD 2.01 (95% C.I. 0.92–3.10), ( = 97.89%)], and severe dengue cases showed higher levels of serum ferritin compared to DwWS [SMD 2.66 (95% C.I. 1.72–4.48), ( = 98.78%)] and DwoWS cases [SMD 6.65 (95% C.I. 1.72–11.59), ( = 99.78%]. Subgroup analysis for the country of study (India vs. others), ferritin testing methods, and ferritin measurement day revealed testing method as a significant contributor to heterogeneity. To conclude, the present study suggests serum ferritin as a prognostic marker for dengue disease severity. Multi‐centric studies involving a large number of dengue patients with a uniform case definition accounting for all the confounding variables might help in determining a universal cut‐off value to discriminate between non‐severe and severe dengue.
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58
Impact of climate change on dengue fever epidemics in South and Southeast Asian settings: A modelling study
Infectious Disease Modelling, 5.06.2023
Tilføjet 5.06.2023
Publication date: Available online 4 June 2023 Source: Infectious Disease Modelling Author(s): Yawen Wang, Shi Zhao, Yuchen Wei, Kehang Li, Xiaoting Jiang, Conglu Li, Chao Ren, Shi Yin, Janice Ho, Jinjun Ran, Lefei Han, Benny Chung-ying Zee, Ka Chun Chong
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59
Dengue fever ophthalmic manifestations: A review and update
Francisco Dias Lucena‐Neto; Luiz Fabio Magno Falcão; Evelly Christinne da Silva Moraes; Joacy Pedro Franco David; Adolfo de Souza Vieira‐Junior; Camilla Costa Silva; Jorge Rodrigues Sousa; Maria Irma Seixas Duarte; Pedro Fernando da Costa Vasconcelos; Juarez Antônio Simões Quaresma;
Reviews in Medical Virology, 24.04.2023
Tilføjet 24.04.2023
Dengue fever, the most common arbovirus disease, affects an estimated 390 million people annually. Dengue virus (DENV) is an RNA virus of the Flaviviridae family with four different serotypes. Dengue haemorrhagic fever is the deadliest form of dengue infection and is characterised by thrombocytopaenia, hypotension, and the possibility of multi‐system organ failure. The mechanism hypothesised for DENV viral replication is intrinsic antibody‐dependent enhancement, which refers to Fcγ receptor‐mediated viral amplification. This hypothesis suggests that the internalisation of DENV through the Fcγ receptor inhibits antiviral genes by suppressing type‐1 interferon‐mediated antiviral responses. DENV NS1 antibodies can promote the release of various inflammatory mediators in the nuclear transcription factor pathway (NF‐κB‐dependent), including monocyte chemoattractant protein (MCP)‐1, interleukin (IL)‐6, and IL‐8. As a result, MCP‐1 increases ICAM‐1 expression and facilitates leukocyte transmigration. In addition, anti‐DENV NS1 antibodies induce endothelial cell apoptosis via a nitric oxide‐regulated pathway. A chain reaction involving pre‐existing DENV heterotypic antibodies and innate immune cells causes dysfunction in complement system activity and contributes to the action of autoantibodies and anti‐endothelial cells, resulting in endothelial cell dysfunction, blood‐retinal barrier breakdown, haemorrhage, and plasma leakage. A spectrum of ocular diseases associated with DENV infection, ranging from haemorrhagic to inflammatory manifestations, has been reported in the literature. Although rare, ophthalmic manifestations can occur in both the anterior and posterior segments and are usually associated with thrombocytopenia. The most common ocular complication is haemorrhage. However, ophthalmic complications, such as anterior uveitis and vasculitis, suggest an immune‐mediated pathogenesis.
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60
Dengue determinants: Necessities and challenges for universal dengue vaccine development
Zahid Hussain; Saima Rani; Fanshu Ma; Wenjing Li; Wenqi Shen; Tian Gao; Jine Wang; Renjun Pei;
Reviews in Medical Virology, 24.04.2023
Tilføjet 24.04.2023
Dengue illness can range from mild illness to life‐threatening haemorrhage. It is an Aedes‐borne infectious disease caused by the dengue virus, which has four serotypes. Each serotype acts as an independent infectious agent. The antibodies against one serotype confer homotypic immunity but temporary protection against heterotypic infection. Dengue has become a growing health concern for up to one third of the world\'s population. Currently, there is no potent anti‐dengue medicine, and treatment for severe dengue relies on intravenous fluid management and pain medications. The burden of dengue dramatically increases despite advances in vector control measures. These factors underscore the need for a vaccine. Various dengue vaccine strategies have been demonstrated, that is, live attenuated vaccine, inactivated vaccine, DNA vaccine, subunit vaccine, and viral‐vector vaccines, some of which are at the stage of clinical testing. Unfortunately, the forefront candidate vaccine is less than satisfactory, and its performance depends on serostatus and age factors. The lessons from clinical studies depicted ambiguity concerning the efficacy of dengue vaccine. Our study highlighted that viral structural heterogeneity, epitope accessibility, autoimmune complications, genetic variants, genetic diversities, antigen competition, virulence variation, host‐pathogen specific interaction, antibody‐dependent enhancement, cross‐reactive immunity among Flaviviruses, and host‐susceptibility determinants not only influence infection outcomes but also hampered successful vaccine development. This review integrates dengue determinants allocated necessities and challenges, which would provide insight for universal dengue vaccine development.
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