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Dokumenter [2] Sider [3] Nyt fra tidsskrifterne [13] Aktuelle smitsomme sygdomme [1]
Dokumenter [2]

Udarbejdet af Dansk Ortopædkirurgisk Selskab (DSO), Dansk Selskab for Infektionsmedicin (DSI), Dansk Selskab for Klinisk Mikrobiologi (DSKM), Dansk Selskab for Klinisk Fysiologi og Nuklearmedicin (DSKFNM) og Dansk Neuroradiologisk Selskab (DNRS).

Bl.a. celler i CSV, spondylodiscitis samt dansk infektionsmedicin på den internationale arena

Sider [3]

…ersen, Thilde Fabricius, Lothar Wiese. Osteomyelitis: Nis Pedersen Jørgensen (tovholder), Nina Weis, Terese Katzenstein, Pernille Ravn, Lotte Ebdrup, Iben Ørsted, Theis Aagaard og Michala Kehler Guidelines for diagnostik og behandling af spondylodiskitis, Pneumoni: Christian Philip Fischer (tovholder), Sebastian Von Huth, Klaus Leth Mortensen, Birgitte Lindegaard Madsen, Lone Mygind, Camilla Hatleberg, Thomas Benfield Pneumoni, Rationel antibiotikaanvendelse:…

… Flemming Rosenvinge. 15.00 - 15.15. Kaffe. 15.15 - 16.00. Antibiotika til bløddele og knogler og biofilm - Undervisning og cases. Flemming Rosenvinge.  . Dag 2: 8.30 - 9.15. Intro til spondylodiskitis - infektionsmedicinerens perspektiv. Michala Kehrer og Zahra Theilgaard. 9.30 - 10.15. Billeddiagnostik  - cases. Nina Nguyen + Kate Rewers. 10.15 – 11.00. Billeddiagnostik - cases. Nina…

…-18. 10.00-10.30 Ankomst. Kaffe og rundstykker. 10.30-10.45 Introduktion til kurset og kort velkomst / Lotte Ebdrup og Pernille Ravn. 10.45-11.00 Introduktion til patienten, der præsenterer sig med feber og rygsmerter / Lotte Ebdrup. 11.00-11.30 Spondylodiskitis (SD) - hvem er i risiko for at udvikle SD? / Gruppe 3. 11.30-12.15 Biofilm / Thomas Bjarnsholt. 12.15-13.00 Spondylodiskitis set fra rygkirurgens perspektiv / Benny Dahl. 13.00-13.45 Frokost. 13.45-14.30 Billeddiagnostik ? PET-C…

…behandling med antibiotika. Det gælder desværre for nær alle infektioner. Og når der ikke er evidens så må vi sætte vores lid til eksperter (og sagt af en ekspert så nærmer de råd sig det tilfældige). Det franske DTS (Duration of Treatment for Spondylodiscitis) er et stort skrift på vejen til at ændre vores lemfældige anbefalinger på ét område. I Frankrig studerede man i et randomiseret klinisk studie om der var forskel på at behandle spondylodiscitis med antibiotika i 6 eller 12 uger. Al…

Nyt fra tidsskrifterne [13]
International Journal of Infectious Diseases
22.12.2024
Affecting intervertebral discs and adjacent vertebrae, Pyogenic spondylodiscitis is a severe bacterial infection, typically Staphylococcus aureus with or without methicillin resistance [1–3]. It is a hematogenous infection carried from other sites of infection. In most cases, the infection spreads through the bloodstream from the skin, respiratory tract, urinary tract, gastrointestinal tract, or oral cavity, extending from the vertebral cartilage to the intervertebral disc [4]. Pyogenic spondylodiscitis s…
BMC Infectious Diseases
19.12.2024
. Abstract. . Background. Fungal spondylitis often occurs in patients with immune dysfunction, and its diagnosis and treatment pose certain challenges. However, even in immunocompromised patients, Aspergillus spondylitis remains rare. This case reports the diagnostic and therapeutic experience of fungal spondylitis in a patient with consolidated cirrhosis and no significant immune impairment. . . …
BMC Infectious Diseases
19.12.2024
. Abstract. Citrobacter youngae (C. youngae) was first described in 1993, and data suggesting that human diseases caused by this bacterium remain scarce. Reports on C. youngae infections mostly described local infections without evidenced bacteremia, especially in immunocompromised patients. Herein, we report a rare case of bacteremia with intervertebral disc and adjacent vertebral infection due to C. youngae (detected by the Vitek® 2 Compact). A 70-year-old man with…
PLoS One Infectious Diseases
14.12.2024
by Miao Cheng, Siqi Xiao, Shaer Kayi, Yujie Guan, Yingxin Liu, Jianmei Chen, Hua Chen, Lei Wang, Xiaojin He . Objective Ankylosing spondylitis (AS) patients often present with microscopic signs of gut inflammation. We used proteomic techniques to identify the differentially expressed proteins (DEPs) in the colon tissues of patients with AS and patients with gut inflammation, and then used investigated the influence of NMRAL1 protein on inflammatory cytokines to explore its potential role in the pathogenesi…
BMC Infectious Diseases
12.11.2024
. Abstract. . Background. Tuberculous spondylitis (TS) and brucellar spondylitis (BS) both cause major long-term morbidity and disability. Though Spondylodiscitis is sensitive to magnetic resonance images, some are difficult to differentiate. This study aims to identify specific bone changes on computed tomography (CT) images, further to differentiate TS from BS. . . . …
BMJ Open
12.09.2024
. Introduction. Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterised by inflammatory low back pain. Non-steroidal anti-inflammatory drugs (NSAIDs) are recommended as a first treatment in axSpA. In case of inadequate response to NSAIDs, biological disease-modifying antirheumatic drugs (bDMARDs) should be introduced according to the recommendations of the European League Against Rheumatism (EULAR) and the American College of Rheumatology. Until 2015, only bDMARD was recommended for …
International Journal of Infectious Diseases
26.08.2024
Fungal spondylitis caused by fungal infection can destroy spinal structures. However, the incidence of this disease in clinical practice is low. The primary causative agent is Candida spp [8], but members of the Aspergillus spp Coccidioides spp, and Cryptococcus spp [1,6] have also been implicated in this disease. Due to the lack of specificity in history, clinical presentation, and diagnosis, patients often lose the opportunity for early diagnosis and treatment, which increases the risk of neurological dys…
Clinical Infectious Diseases
24.04.2024
Abstract . The ESC diagnostic criteria for infective endocarditis (IE) added spondylodiscitis as minor diagnostic criterion. Of patients with Staphylococcus aureus, streptococcal or Enterococcus faecalis bacteremia, 11 of 1807 episodes were reclassified to definite IE of which nine were not treated as IE. Spondylodiscitis as a minor criterion decreases specificity of the criteria.
Clinical Infectious Diseases
27.11.2024
Abstract . Background . Fever is common in infective endocarditis (IE), yet little is known about fever duration in such patients. We aim to identify predictors of persistent fever in patients with suspected IE.Methods . This study was conducted at the Lausanne University Hospital, Switzerland, from January 2014 to June 2023. All patients with suspected IE being febrile upon presentation were included. Fever (>38°C) was considered persistent if it continued for at least 96h from antimicrobial treatment ini…
PLoS One Infectious Diseases
9.08.2024
… (GLP-1-RAs) versus dipeptidyl peptidase-4 inhibitors (DPP-4is). Methods We performed a population-based cohort study using administrative health data from British Columbia. Patients with an IMID (i.e., rheumatoid arthritis, psoriatic disease, ankylosing spondylitis, inflammatory bowel disease, or a systemic autoimmune rheumatic disease) and type 2 diabetes who newly initiated a GLP-1-RA or DPP-4i between January 1, 2010, and December 31, 2021 were identified using ICD-9/10 codes. The primary outcome was a…
BMC Infectious Diseases
17.07.2024
…tis caused by Ruthenibacterium lactatiformans. . . . Case presentation. An 82-year-old man with a history of diabetes, chronic renal failure, and prior spinal surgery for spondylolisthesis and spinal stenosis presented with fever and lower back pain. Magnetic resonance imaging revealed multiple vertebral osteomyelitis lesions. Initial blood cultures identified methicillin-resistant Staphylococcus aureus (MRSA), which prompt…
BMC Infectious Diseases
28.06.2024
…f the spinal column revealed irregular bone destruction affecting the L2, L3, and L5 vertebral bodies. Additionally, low T1 and high T2 intensity lesions were observed at the intervertebral discs between L3 and L5. The presumptive diagnosis of tuberculous spondylitis was made based on the imaging findings, despite negative results in all mycobacterium tests. However, the patient exhibited no improvement after receiving regular anti-tuberculosis treatment for 3 months. Subsequent MRI revealed an expansive ab…
Infection
10.05.2024
…cell (WBC) count. The aim was to compare the predictive values of CRP, WBC count, PCT, IL-6, and TNF-α in SSI detection. . . . Methods. A total of 130 patients undergoing dorsal spondylodesis from 2019 to 2024 were enrolled in a prospective diagnostic study at a maximum care spine center. IMs were measured preoperatively and on the postoperative days (PODs) 1, 2, 3, 5, and 7. Patients with high suspicion of SSI underwent revision …

Aktuelle smitsomme sygdomme [1]

Aktuelle smitsomme sygdomme [1]
Medscape Infectious Diseases
20.11.2024
Most patients with rheumatoid arthritis or spondyloarthritis had significant antibody responses to COVID vaccine boosters, whether or not their immunomodulatory medications were held. . Medscape Medical News

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