Søgning
Søgning på udtrykket 'sepsis' giver 43 resultater
Dokumenter [6]
Sider [6]
Nyt fra tidsskrifterne [+20]
Aktuelle smitsomme sygdomme [9]
Disse rekommandationer retter sig mod voksne indlagt med mistænkt sepsis og septisk shock.
Se flowchart på infmed.dk/bilag#sepsis_flowchart_(2021).pdf
Rekommandationer for profylakse og vaccination ved aspleni.
Denne vejledning dækker anbefalinger omhandlende vaccinationer, antibiotika profylakse og patientinformation om generelle forholdsregler for at beskytte personer med aspleni mod infektioner.
Version 1.2, 22.10.2024. Ændringer siden version 1.1:
Vaccination mod Haemophilus influenzae ændret til 1 dosis (fejlagtigt angivet 3 doser).
Menveo beskytter efter 1 dosis (fejlagtigt angivet som nødvendigt med 2. dosis efter 2-3 mdr).
Link til bila…
For infektionsmedicinsk interesserede yngre læger
Bilag med flowchart til vurdering og behandling af sepsis og septisk shock, se også infmed.dk/guidelines#sepsis_guidelines_(2021).pdf
Om bl.a. svære infektioner, sepsis, infektioner hos neutropene samt etiske dilemmaer i infektionsmedicin
…fektionsepidemiologi, SSI.
15.15 – 15.30.
Kaffe og kage og frugt.
15.30 – 16.30.
.
Antimicrobial stewardship i praksis.
Afdelingslæge, Jon Gitz Holler, Nordsjællands Hospital.
12. juni 2024 (dag 2):
Sepsis, antibiotika, urinvejsinfektioner.
Tid.
Emne og underviser.
08.30 – 12.30.
SEPSIS.
08.30 – 09.30.
Det septiske shock.
Professor, overlæge Anders Perner, Intensiv, RH.
09.30 – 09.…
…
Rationel antibiotikaanvendelse:
Trine Langfeldt Hagen (tovholder), Shakil Shakar, Susanna Deutch, Kristina Öbrinck, Mathias Hertz, Isik Johansen, Christian Kraef, Jon Gitz Holler, Mette Vang Larsen, Thomas Benfield og Andreas Knudsen .
Sepsis:
Rikke Krogh-Madsen (tovholder), Lars Skov Dalgaard, Michael Dalager Pedersen, Christian Philip Fischer, Gitte Kronborg, Jannik Helweg Larsen, Stig Lønberg Nielsen, Christian Søborg, Lars Toft.
Sepsis guideline,
Sepsis flowchart,
…
…rsus.
2026:
Sted.
Infektionsmedicinsk afd. 8632, Rigshospitalet
Delkursusledelse.
Marie Helleberg og Trine Mogensen
Program.
Afventer
Tidligere kurser.
30. og 31. januar 2023
25. og 26. januar 2017
Infektionshygiejne/profylakse, sepsis og urogenitale infektioner:
Dato for næste kursus.
2027:
Program.
Afventer
Sted.
Hvidovre Hospital
Delkursusledelse.
Rikke Krogh-Madsen og Michael Dalager-Pedersen
Tidligere kurser.
11. og 12. juni 2024
8. og 9. juni 2021
15. og…
Risikoen for bakteriel infektion og sepsis er svært forhøjet ved manglende miltfunktion som følge af splenektomi samt kongenit eller funktionel aspleni. Alvorlige infektioner skyldes primært Streptococcus pneumoniae, Haemophilus influenzae og Neisseria meningitidis.
Risikoen for svær infektion ved malaria og dyrebid er også markant forhøjet.
Vaccination, antibiotika profylakse/tidlig behandling og adækvat patient information er afgørende for forebyggelse af infektioner.
Antibiotika behandlin…
Nedenstående Sequential Organ Failure Assessment (SOFA) score udregnes på baggrund af den let modificerede SOFA-score, som fremgår af Dansk Selskab for Infektionsmedicins vejledninger vedrørende sepsis.
Professor Court Petersen kommenterer: Velskreven oversigtsartikel, der bør læses af alle, der har med sepsispatienter at gøre.
Artiklen "afliver" det noget forældede SIRS begreb.
Andre 2013-artikler fra NEJM kan med stor fordel læses som supplement:
"Circulatory shock" N Engl J Med. 2013;369(18):1726-34
"Resuscitation fluids" N Engl J Med. 2013;369(13):1243-51
"Ventilator-induced lung injury" N Engl J Med. 2013;369(22):2126-36
Professor Niels Obel kommenterer: Denne artikel er tankevækkende - fordi vi nu igen står i en situation, hvor noget, vi mente var en "sepsis-sandhed" fra et randomiseret trial, ser ud til at være forkert.
Nyt fra tidsskrifterne [+20]
Der er mere end 20 resultater, måske du vil se flere resultater her?
BMC Infectious Diseases
6.12.2024
. Abstract. . Background. Despite the increasing use of metagenomic next-generation sequencing (mNGS) in sepsis, identifying clinically relevant pathogens remains challenging. This study was aimed to evaluate the clinical utility of simultaneous plasma and bronchoalveolar lavage fluid (BALF) detection using mNGS. . . . Methods. This retrospe…
Clinical Infectious Diseases
6.12.2024
Abstract . Background . Little is known about the frequency, hospital-level variation, predictors, and clinical outcomes of antibiotic de-escalation in suspected sepsis.Methods . We retrospectively analyzed all adults admitted to 236 US hospitals between 2017-2021 with suspected sepsis (defined by a blood culture draw, lactate measurement, and intravenous antibiotic administration) who were initially treated with ≥2 days of anti-MRSA and anti-pseudomonal antibiotics but had no resistant organisms requirin…
Clinical Infectious Diseases
6.12.2024
Abstract . Background . Timely antibiotic initiation is critical to sepsis management, but there are limited data on the impact of giving β-lactams first vs vancomycin first amongst patients prescribed both agents.Methods . We retrospectively analyzed all adults admitted to 5 US hospitals from 2015-2022 with suspected sepsis (blood culture collected, antibiotics administered, and organ dysfunction) treated with vancomycin and a broad-spectrum β-lactam within 24h of arrival. We estimated associations betwe…
New England Journal of Medicine
5.12.2024
New England Journal of Medicine, Volume 391, Issue 22, Page 2133-2146, December 5, 2024.
Clinical Microbiology and Infection
4.12.2024
Bacteraemia and sepsis have traditionally required continued intravenous (IV) antibiotics.
American Journal of Tropical Medicine and Hygiene
4.12.2024
. . Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 111 Issue: 6 Pages: 1252-1255. .
Lancet Respiratory Medicine
4.12.2024
Jackie Duda's terrifying ordeal began in May, 2021. Parts of it—the anxiety, the flashbacks—continue to live with her today. Her enemy in this near-lethal fight: sepsis; something she knew little about back then, but is determined that all people should know about now.
Infection
4.12.2024
. Abstract. . Purpose. Early recognition of sepsis is critical to patient outcome, with mortality increasing with every hour of delay in treatment. The aim of this study was to investigate the use of a point-of-care molecular host response assay to differentiate sepsis from inflammation after surgery. . . . Methods. Three molecular host response assays (Sep…
Infection
4.12.2024
. Abstract. . Objective. We hypothesized that previously healthy infants
Clinical Infectious Diseases
28.11.2024
Sepsisantibiotic de-escalationsafetyefficacy
Critical Care Medicine
28.11.2024
Objectives: . This study aimed to investigate the relationship between ABO blood group and sepsis-associated thrombocytopenia (SAT). Design and Setting: . The primary outcome was SAT within the first 72 hours of ICU admission. Patients: . The retrospective study included 9113 patients diagnosed with sepsis from January 2014 to December 2022. A total of 6296 patients eventually were included into the study, who were divided into four groups based on ABO blood group. Interventions: . None. Measurements an…
Journal of Infectious Diseases
19.11.2024
Abstract . Background . Sepsis is characterized by a life-threatening syndrome caused by an unbalanced host response to infection. Fibroblast Growth Factor 8 (FGF8) has been newly identified to play important roles in inflammation and innate immunity, but its role in host response to sepsis is undefined.Methods . A cecal ligation and puncture (CLP) -induced mouse sepsis model was established to evaluate the immunomodulatory function of FGF8 during sepsis. The underlying molecular mechanisms were elucidated …
Critical Care Explorations
17.11.2024
OBJECTIVES: . Sepsis is an evolving process and proposed subtypes may change over time. We hypothesized that previously established sepsis subtypes are dynamic, prognostic of outcome, and trajectories are associated with host response alterations. DESIGN: . A secondary analysis of two observational critically ill sepsis cohorts: the Molecular diAgnosis and Risk stratification of Sepsis (MARS) and the Medical Information Mart for Intensive Care-IV (MIMIC-IV). SETTING: . ICUs in the Netherlands and United …
PLoS One Infectious Diseases
12.11.2024
by Wenchi Liu, Xing Yu, Jinhong Chen, Weizhi Chen, Qiaoyi Wu . Background People with traumatic brain injury (TBI) are at high risk for infection and sepsis. The aim of the study was to develop and validate an explainable machine learning(ML) model based on clinical features for early prediction of the risk of sepsis in TBI patients. Methods We enrolled all patients with TBI in the Medical Information Mart for Intensive Care IV database from 2008 to 2019. All patients were randomly divided into a training…
BMC Infectious Diseases
8.11.2024
… Abstract. . Background. The stress hyperglycemia ratio (SHR) is associated with poor outcomes in critically ill patients. However, the relationship between SHR and mortality in patients with sepsis-associated acute kidney injury (SA-AKI) remains unclear. . . . Methods. The data of patients with SA-AKI, identified based on the KDIGO criteria, were retrospective…
Clinical Infectious Diseases
7.11.2024
BMJ Open
31.10.2024
. Introduction. Linezolid is a broadly used antibiotic to treat complicated infections caused by gram-positive bacteria. Therapeutic drug monitoring of linezolid concentrations is recommended to maximise its efficacy and safety, mainly haematological toxicity. Different pharmacokinetic/pharmacodynamic targets have been proposed to improve linezolid exposure: the ratio of the area under the concentration–time curve during a 24-hour period to minimum inhibitory concentration (MIC) between 80 and 120; percen…
BMC Infectious Diseases
30.10.2024
. Abstract. . Background. Information on the comparison of blood microbiota between human immunodeficiency virus (HIV)-infected and HIV-uninfected patients with suspected sepsis by metagenomic next-generation sequencing (mNGS) is limited. . . . Methods. Retrospectively analysis was conducted in HIV-infected and HIV-uninfected patients with s…
Critical Care Explorations
25.10.2024
OBJECTIVES: . To evaluate the effect of procalcitonin-guided management on the duration of antibiotic therapy in critically ill cancer patients with sepsis. DESIGN: . Randomized, controlled, single-blinded trial. SETTING: . A comprehensive multidisciplinary cancer hospital in Jordan. PATIENTS: . Adults with cancer treated in the ICU who were started on antibiotics for suspected infection, met the SEPSIS-3 criteria, and were expected to stay in the ICU greater than or equal to 48 hours. INTERVENTIONS: .…
Virulence
21.10.2024
Volume 15, Issue 1, December 2024 .
Aktuelle smitsomme sygdomme [9]
Aktuelle smitsomme sygdomme [9]
Medscape Infectious Diseases
31.10.2024
The virtual model updated data every 15 minutes, providing a dynamic predictor for patient outcomes. . Medscape Medical News
Medscape Infectious Diseases
1.08.2024
A meta-analysis found that sepsis alert systems were associated with improved patient outcomes and adherence to sepsis management protocols in emergency departments. . Medscape Medical News
Medscape Infectious Diseases
12.07.2024
Urine culture-negative patients with bacteremia had the highest rate of ICU admission and representation following discharge and the longest hospital stay, reported a study. . Medscape Medical News
Medscape Infectious Diseases
17.06.2024
Delays in antibiotic administration increased the mortality risk by threefold in children with sepsis presenting to the ED. . Medscape Medical News
Medscape Infectious Diseases
15.04.2024
The first-ever AI diagnostic tool for sepsis was granted marketing authorization through the FDA's De Novo pathway. . Medscape Medical News
Medscape Infectious Diseases
1.02.2024
Based on new findings, the task force now suggests that pediatric sepsis be defined by a Phoenix Sepsis Score of at least 2 points in children with suspected infection. . MDedge News
Eurosurveillance latest updates
29.11.2024
…tivitis and one fatal case with sepsis. In a logistic regression analysis, nursing in an incubator was significantly associated with acquisition of S. marcescens (odds ratio (OR): 2.99; 95% confidence interval (CI): 1.14–8.25; p 4 cases per week were identified (peak events), several peaks with different clonal clusters occurred. The emergence of similar outbreaks in Belgian hospitals underscores the need of continuous surveillance and NICU-specific infection prevention and control (IPC) measures. .
Eurosurveillance latest updates
5.10.2024
…young children was reported by several countries. Viral infections including influenza and varicella, known risk factors for iGAS infection, also increased. . . Aim. To estimate the proportion of GAS skin and soft tissue infections (SSTI) and pneumonia/sepsis in children (≤ 5 years) attributable to varicella, and the proportion of GAS pneumonia/sepsis in children and adults attributable to potentially predisposing respiratory viruses influenza A and B, RSV, hMPV and SARS-CoV-2 in the Netherlands. . …
Medscape Infectious Diseases
4.06.2024
Public reporting of sepsis outcomes, including hospital deaths, isn't telling the whole story. . Medscape