Søgning på udtrykket 'sepsis' giver 63 resultater
Dokumenter [4]
Sider [4]
Kalender [13]
Nyt fra tidsskrifterne [+20]
Aktuelle smitsomme sygdomme [+20]
Dokumenter [4]
Disse rekommandationer retter sig mod voksne indlagt med mistænkt sepsis og septisk shock.
Se flowchart på infmed.dk/bilag#sepsis_flowchart_(2021).pdf
På vegne af Dansk Selskab for Infektionsmedicin: Lars Skov Dalgaard, Michael Dalager, Christian Philip Fischer, Rikke Krogh-Madsen, Gitte Kronborg, Jannik Helweg Larsen, Stig Lønberg Nielsen, Christian Søborg, Lars Toft.
For infektionsmedicinsk interesserede yngre læger
Bilag med flowchart til vurdering og behandling af sepsis og septisk shock, se også infmed.dk/guidelines#sepsis_guidelines_(2021).pdf
Sider [4]
Thomas Benfield og Andreas Knudsen .
Sekundær immundefekt:
Søren Jensen-Fangel (tovholder), Christian Philip Fischer, Marie Helleberg, Jannik Helweg-Larsen, Lykke Larsen, Daria Podlekareva, Line Dahlerup Rasmussen, Pernille Ravn
Sepsis:
Rikke Krogh-Madsen (tovholder), Lars Skov Dalgaard, Michael Dalager Pedersen, Christian Philip Fischer, Gitte Kronborg, Jannik Helweg Larsen, Stig Lønberg Nielsen, Christian Søborg, Lars Toft.
Sepsis guideline,
Sepsis flowchart,
s
30. og 31. januar 2023 (2 dage):
Sted
Infektionsmedicinsk afd. 8632, Rigshospitalet
Delkursusledelse
Marie Helleberg og Trine Mogensen
Program
Kan downloades her
Tidligere kurser
25. og 26. januar 2017
Infektionshygiejne/profylakse, sepsis og urogenitale infektioner:
Dato for næste kursus
Sommer 2024:
Sted
Endnu ikke afklaret
Delkursusledelse
Rikke Krogh-Madsen og Michael Dalager-Pedersen
Tidligere kurser
8. og 9. juni 2021
15. og 16. maj 2018
Kardiopulmonale in
Nedenstående Sequential Organ Failure Assessment (SOFA) score udregnes på baggrund af den let modificerede SOFA-score, som fremgår af Dansk Selskab for Infektionsmedicins vejledninger vedrørende sepsis.
Professor Court Petersen kommenterer: Velskreven oversigtsartikel, der bør læses af alle, der har med sepsispatienter at gøre.
Artiklen "afliver" det noget forældede SIRS begreb.
Andre 2013-artikler fra NEJM kan med stor fordel læses som supplement:
"Circulatory shock" N Engl J Med. 2013;369(18):1726-34
"Resuscitation fluids" N Engl J Med. 2013;369(13):1243-51
"Ventilator-induced lung injury" N Engl J Med. 2013;369(22):2126-36
Professor Niels Obel kommenterer: Denne artikel er tankevækkende - fordi vi nu igen står i en situation, hvor noget, vi mente var en "sepsis-sandhed" fra et randomiseret trial, ser ud til at være forkert.
Kalender [13]
3. maj 2019, Hindsgavl, Middelfart
1. marts 2019, Novo Nordisk Fonden, Tuborg Havnevej 19, 2900 Hellerup
5. september 2018, Online
15. maj 2018, Aarhus Universitetshospital
4. april 2017, Auditorium 1, Rigshospitalet
8. september 2016, Online
11. marts 2015, Auditorium 2, Rigshospitalet
11. april 2013, Hvidovre Hospital
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BMC Infectious Diseases
21.09.2023
. Abstract. . Background. The gastrointestinal tract contains a massive microbiota, and targeting the gut could be a potential intervention for sepsis. However, the interaction between sepsis and the intestinal microbiota is defined as an “incompletely understood bidirectional relationship”. . . . Methods. This retrospective observationa
BMC Infectious Diseases
21.09.2023
. Abstract. . Background. The course of monkeypox can be severe. Our aim was to retrospectively compare the risk of hospital admission, the need for ventilation, sepsis, pneumonitis and death between the recent outbreak and historical outbreaks. . . . Materials and Methods. Cases of monkeypox were retrieved from the TriNetX database and assi
Virulence
20.09.2023
Volume 14, Issue 1, December 2023 .
Infection
20.09.2023
. Abstract. . Purpose. Timely and accurate data on the epidemiology of sepsis are essential to inform policy decisions and research priorities. We aimed to investigate the validity of inpatient administrative health data (IAHD) for surveillance and quality assurance of sepsis care. . . . Methods. We conducted a retrospective validation study in a disproport
BMC Infectious Diseases
19.09.2023
. Abstract. . Background. The gastrointestinal tract contains a massive microbiota, and targeting the gut could be a potential intervention for sepsis. However, the interaction between sepsis and the intestinal microbiota is defined as an “incompletely understood bidirectional relationship”. . . . Methods. This retrospective observationa
BMC Infectious Diseases
18.09.2023
. Abstract. . Background. The course of monkeypox can be severe. Our aim was to retrospectively compare the risk of hospital admission, the need for ventilation, sepsis, pneumonitis and death between the recent outbreak and historical outbreaks. . . . Materials and Methods. Cases of monkeypox were retrieved from the TriNetX database and assi
BMJ Open
14.09.2023
. Introduction. Sepsis is one of the most common risk factors for acute respiratory distress syndrome (ARDS). Neutrophil elastase (NE) is believed to be an important mediator of ARDS. When sepsis occurs, a large number of inflammatory factors are activated and released, which makes neutrophils migrate into the lung, eventually leading to the occurrence of ARDS. Sivelestat sodium is an NE inhibitor that can inhibit the inflammatory reaction during systemic inflammatory response syndrome and alleviate lung in
Infection and Immunity
14.09.2023
Infection and Immunity, Ahead of Print.
BMJ Open
11.09.2023
. Objective. Sepsis remains a high cause of death, particularly in immunocompromised patients with cancer. The study was to develop a model to predict hospital mortality of septic patients with cancer in intensive care unit (ICU). . Design. Retrospective observational study. . Setting. Medical Information Mart for Intensive Care IV (MIMIC IV) and eICU Collaborative Research Database (eICU-CRD). . Participants. A total of 3796 patients in MIMIC IV and 549 patients in eICU-CRD were included. . Primary out
Infection
9.09.2023
. Abstract. . Purpose. Timely and accurate data on the epidemiology of sepsis are essential to inform policy decisions and research priorities. We aimed to investigate the validity of inpatient administrative health data (IAHD) for surveillance and quality assurance of sepsis care. . . . Methods. We conducted a retrospective validation study in a disproport
BMJ Open
5.09.2023
. Objective. To determine if the introduction of an emergency department (ED) sepsis screening tool and management bundle affects antibiotic prescribing and use. . Design. Multicentre, cohort, before-and-after study design. . Setting. Three tertiary hospitals in Queensland, Australia (median bed size 543, range 520–742). . Participants. Adult patients, presenting to the ED with symptoms and signs suggestive of sepsis who had blood cultures collected. These participants were further assessed and stratif
American Journal of Respiratory and Critical Care Medicine
2.09.2023
American Journal of Respiratory and Critical Care Medicine, Volume 208, Issue 5, Page 628-630, September 1, 2023.
Critical Care Explorations
31.08.2023
Competing definitions of sepsis have significant clinical implications and impact both medical coding and hospital payment. Although clinicians may prefer Sepsis-2, payer use of Sepsis-3 to validate clinical diagnoses may result in denial of payment or requests to recoup previously paid funds from healthcare providers. The Sepsis-2.5 project was a cooperative effort between a hospital system and a private payer to develop a community-based, literature-supported consensus definition for sepsis characterized
Critical Care Explorations
31.08.2023
OBJECTIVES: . We analyzed whether patients with the International Classification of Diseases, 10th Edition (ICD-10) discharge diagnosis code for sepsis are different in regard to demographics and outcome variables when comparing those with sepsis only to those also diagnosed with COVID-19 or those with a COVID-19 diagnosis alone. DESIGN: . Retrospective cohort study. SETTING: . Nine hospitals in an academic health system. PATIENTS: . Patients with a final ICD-10 discharge diagnostic code for sepsis only
Journal of Infectious Diseases
31.08.2023
AbstractBackgroundPatients with sepsis accompanying with acute lung injury (ALI) usually suffer from increased mortality. Ferroptosis is a vital regulator in sepsis-induced ALI. Exploring the association of ferroptosis and sepsis-induced ALI is crucial for the management of sepsis-induced ALI.MethodsWhole blood was collected from sepsis patients. Mice were treated with caecal ligation and puncture (CLP) for modeling sepsis. Primary murine pulmonary microvascular endothelial cells (PMVECs) were treated with
Journal of Infectious Diseases
27.08.2023
AbstractGlucocorticoid (GC) therapy had been strongly recommended for pediatric sepsis (grade 1A). However, the recommendation was changed to grade 2C in 2020 due to weak evidence. About 32.8% pediatric septic patients develops relative adrenal insufficiency (RAI). But whether GC therapy should be determined by RAI status is controversial. This study utilized 21-day-old SF1CreSRBIfl/fl mice as the first pediatric RAI mouse model to assess the pathogenesis of RAI and evaluate GC therapy. RAI mice exhibited s
Journal of Infectious Diseases
25.08.2023
AbstractBackgroundSepsis-induced cardiomyopathy (SIC) is a cardiac dysfunction caused by sepsis, with mitochondrial dysfunction being a critical contributor. Pyruvate dehydrogenase kinase 4 (PDK4) is a kinase of pyruvate dehydrogenase (PDH) with multifaceted actions in mitochondrial metabolism. However, its role in SIC remains unknown.MethodsSerum PDK4 levels were measured and analyzed in 27 SIC children, 30 septic children, and 29 healthy children. In addition, the effects of PDK4 knockdown or inhibition o
Critical Care Explorations
24.08.2023
OBJECTIVES: . Clinical sepsis phenotypes may be defined by a wide range of characteristics such as site of infection, organ dysfunction patterns, laboratory values, and demographics. There is a paucity of literature regarding the impact of site of infection on the timing and pattern of clinical sepsis markers. This study hypothesizes that important phenotypic variation in clinical markers and outcomes of sepsis exists when stratified by infection site. DESIGN: . Retrospective cohort study. SETTING: . Fiv
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Morbidity and Mortality Weekly Report (MMWR)
22.09.2023
This report describes sepsis-related date rates among adults 65 years and older.
Medscape Infectious Diseases
13.09.2023
Medscape spoke with CDC contributors Raymund Dantes, MD, MPH, and Hallie Prescott, MD, MSc, about the new Hospital Sepsis Program Core Elements to help clinicians improve outcomes from sepsis. . CDC Expert Commentary
Medscape Infectious Diseases
1.09.2023
While 73% of US hospitals have sepsis teams, only 55% of them report that their team leaders get dedicated time to manage the programs for a medical emergency that affects at least 1.7 million people. . Medscape Medical News
Morbidity and Mortality Weekly Report (MMWR)
25.08.2023
This report describes sepsis programs in hospitals and identifies areas of opportunities to improve sepsis programs.
Medscape Infectious Diseases
5.07.2023
Compared with influenza and sepsis, severe COVID-19 infections resulted in similar risk for neurological and cardiovascular conditions, suggesting a common need for long-term support. . Medscape Medical News
Medscape Infectious Diseases
1.07.2023
A new review provides insights into intravenous fluid therapy for sepsis, including how much to give at each stage of treatment. . Medscape Medical News
Medscape Infectious Diseases
6.10.2022
Experts expressed hope that, with additional research, the new testing method could eventually cut the time for sepsis detection from days to hours, potentially saving lives. .
Medscape Infectious Diseases
7.01.2022
Rates of resistance to ampicillin-gentamicin are extremely high in low- and middle-income countries. .
Medscape Infectious Diseases
24.06.2021
A sepsis-prediction model used widely by hospitals and health systems in the United States performed poorly in predicting sepsis onset in an external validation study.
Morbidity and Mortality Weekly Report (MMWR)
13.06.2019
Whole genome sequencing indicated a potential common source of bacterial contamination among four cases of septic transfusion reactions occurring in three states.
Morbidity and Mortality Weekly Report (MMWR)
28.06.2018
Morbidity and Mortality Weekly Report (MMWR)
22.09.2023
This report describes sepsis-related date rates among adults 65 years and older.
Medscape Infectious Diseases
13.09.2023
Medscape spoke with CDC contributors Raymund Dantes, MD, MPH, and Hallie Prescott, MD, MSc, about the new Hospital Sepsis Program Core Elements to help clinicians improve outcomes from sepsis. . CDC Expert Commentary
Eurosurveillance latest updates
8.09.2023
e group A Streptococcus infections in Portugal (n = 89) were higher than in pre-COVID-19 seasons. Between September 2022 and May 2023, the dominant diagnoses were pneumonia (25/79), mostly with empyema (20/25), and sepsis (22/79). A number of cases required admission to intensive care (27/79) and surgery (35/79), and the case fatality rate was 5.1% (4/79). Genomic sequencing (n = 55) revealed multiple genetic lineages, dominated by the M1UK sublineage (26/55) and more diverse emm12 isolates (12/55).
Medscape Infectious Diseases
1.09.2023
While 73% of US hospitals have sepsis teams, only 55% of them report that their team leaders get dedicated time to manage the programs for a medical emergency that affects at least 1.7 million people. . Medscape Medical News
Morbidity and Mortality Weekly Report (MMWR)
25.08.2023
This report describes sepsis programs in hospitals and identifies areas of opportunities to improve sepsis programs.
Medscape Infectious Diseases
5.07.2023
Compared with influenza and sepsis, severe COVID-19 infections resulted in similar risk for neurological and cardiovascular conditions, suggesting a common need for long-term support. . Medscape Medical News
Medscape Infectious Diseases
1.07.2023
A new review provides insights into intravenous fluid therapy for sepsis, including how much to give at each stage of treatment. . Medscape Medical News
Eurosurveillance latest updates
2.06.2023
We report nine severe neonatal infections caused by a new variant of echovirus 11. All were male, eight were twins. At illness onset, they were 3–5 days-old and had severe sepsis and liver failure. This new variant, detected in France since April 2022, is still circulating and has caused more fatal neonatal enterovirus infections in 2022 and 2023 (8/496; 1.6%, seven associated with echovirus 11) compared with 2016 to 2021 (7/1,774; 0.4%). National and international alerts are warranted.
ProMED
2.06.2023
Enterovirus -- FranceSituation at a glance---------------------On [5 May 2023], France reported an increase in cases of severe neonatal sepsis associated with Enterovirus (Echovirus-11 (E-11)). A total of 9 cases of neonatal sepsis with hepatic impairment and multi-organ failure were reported between [July 2022] and [April 2023] from 4 hospitals in 3 regions of France. As of [5 May 2023], 7 cases have died and 2 were still hospitalized in neonatal unit. The current increase in incidence and severity in