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Søgning på udtrykket 'sepsis' giver 59 resultater
Dokumenter [6]
Sider [11]
Nyt fra tidsskrifterne [+20]
Aktuelle smitsomme sygdomme [+20]
Disse rekommandationer retter sig mod voksne indlagt med mistænkt sepsis og septisk shock. Se flowchart på infmed.dk/bilag#sepsis_flowchart_(2021).pdf
Rekommandationer for profylakse og vaccination ved aspleni. Denne vejledning dækker anbefalinger omhandlende vaccinationer, antibiotika profylakse og patientinformation om generelle forholdsregler for at beskytte personer med aspleni mod infektioner. Version 1.3, 11.06.25. Ændringer siden version 1.2: Aldersgrænse på 30 år tilføjet ved rutinemæssig vaccination mod meningokokker ved aspleni. Dosis af profylaktisk penicillin ændret med henblik større praktisk anvendelighed.
For infektionsmedicinsk interesserede yngre læger
Bilag med flowchart til vurdering og behandling af sepsis og septisk shock, se også infmed.dk/guidelines#sepsis_guidelines_(2021).pdf
Om bl.a. svære infektioner, sepsis, infektioner hos neutropene samt etiske dilemmaer i infektionsmedicin
[…] Skou Voss, Infektionsepidemiologi, SSI. 15.15 – 15.30 Kaffe og kage og frugt. 15.30 – 16.30 Antimicrobial stewardship i praksis. Afdelingslæge, Jon Gitz Holler, Nordsjællands Hospital. 12. juni 2024 (dag 2) Sepsis, antibiotika, urinvejsinfektioner Tid Emne og underviser 08.30 – 12.30 SEPSIS 08.30 – 09.30 Det septiske shock. Professor, overlæge Anders Perner, Intensiv, RH. 09.30 – 09.45 Pause 09.45 – 10.30 Definition og behandling af sepsis I. Overlæge Christian Fischer, […]
[…] Mohey, Mathias Hertz, Isik Johansen, Sebastian von Huth, Jacob Søholm, Theis Aagaard Sonnichsen, Christian Kraef, Jon Gitz Holler, Mette Vang Larsen, Thomas Benfield, Andreas Knudsen, Toke Barfod Sepsis Rikke Krogh-Madsen (tovholder), Lars Skov Dalgaard, Michael Dalager Pedersen, Christian Philip Fischer, Gitte Kronborg, Jannik Helweg Larsen, Stig Lønberg Nielsen, Christian Søborg, Lars Toft. Sepsis guideline Sepsis flowchart Staphylococcus aureus bakteriæmi Louise Thorlacius-Ussing (tovholder), […]
[…] Delkursusledelse Marie Helleberg og Trine Mogensen Program Afventer Tidligere kurser 30. og 31. januar 2023 25. og 26. januar 2017 Infektionshygiejne/profylakse, sepsis og urogenitale infektioner Dato for næste kursus 2027 Program Afventer Sted Hvidovre Hospital Delkursusledelse Rikke Krogh-Madsen og Michael Dalager-Pedersen Tidligere kurser 11. og […]
[…] af profylaktiske tiltag for at beskytte personer med aspleni mod infektioner. De profylaktiske tiltag kan inddeles i vaccinationer, antibiotika profylakse og patientinformation om generelle forholdsregler. Quickguide Risikoen for bakteriel infektion og sepsis er svært forhøjet ved manglende miltfunktion som følge af splenektomi samt kongenit eller funktionel aspleni. Alvorlige infektioner skyldes primært Streptococcus pneumoniae, Haemophilus influenzae og Neisseria meningitidis. Risikoen for svær […]
[…] er korreleret med mere udbredte infiltrater og dårligere outcome (bl.a. indlæggelsesvarighed, sepsis, indlæggelse på intensivafdeling, mortalitet), også når CURB-65 kun er 0-1.10 Behandling Antibiotika Se også antibiotisk behandling ved ukendt ætiologi og antibiotisk behandling ved kendt ætiologi. Initial behandling Start behandling med antibiotika hurtigst muligt efter de initiale undersøgelser er afsluttet (B). Rationale: Hårde grænser for hvornår antibiotika skal administreres initialt […]
Nedenstående Sequential Organ Failure Assessment (SOFA) score udregnes på baggrund af den let modificerede SOFA-score, som fremgår af Dansk Selskab for Infektionsmedicins vejledninger vedrørende sepsis.
[…] jord penetrerer hud. Asymptomatisk, evt. let øvre abdominalt ubehag. Hud: dermatitis, larva currens. Lunger: pneumonitis (Löfflers syndrom). GI: diarre, smerter. Immunsupprimerede: hyperinfektions-syndrom (pneumoni, ileus, sepsis, død) Børneorm (Enterobius vermicularis) Analaftryk for æg (nat/tidligt morgen), kan gentages x 2 hvis negativ Mebendazol 100 mg EGO, gentages efter 2 og 4 uger. Alternativt albendazol 400 mg EGO; gentages efter 2 uger. Global udbredelse. Hyppigst børn 5-10 år. Fæko-oral […]
[…] neurologi eller MR påvist intraspinal patologi skal starte empirisk antibiotisk behandling prompte efter, at der er foretaget bloddyrkning. Tilsvarende opstartes målrettet antibiotisk behandling ved positive bloddyrkninger. For øvrige patienter bør antibiotisk behandling tilbageholdes, indtil der er lavet seriel bloddyrkning over 18-24 timer, og evt. længere antibiotikapause, hvis der planlægges udførsel af invasiv diagnostik. Andelen af mikrobiologisk verificerede infektioner øges ved systematisk […]
[…] thorax Ekspektorat og urin til D+R Afhængig af klinik: CT-cerebrum EEG (NCSE) Ekkokardografi ØNH-tilsyn Understøttende behandling Volumen og elektrolyt terapi Smerter/Kramper Indikation for intensiv terapi Ved sepsis eller septisk shock anvendes isoton NaCl (0,9 %) som infusionsvæske. Ved hyponatriæmi og bevidsthedspåvirkning se** Giv ikke væsker som bliver hypotone efter indgift (Ringer, Na-K-Glukose eller Glukose), da risikoen for hjerneødem øges. Smertebehandling: paracetamol 1 g x 4 evt + morfin 10 mg […]
[…] thorax Ekspektorat og urin til D+R Afhængig af klinik: CT-cerebrum EEG (NCSE) Ekkokardografi ØNH-tilsyn Understøttende behandling Volumen og elektrolyt terapi Smerter/Kramper Indikation for intensiv terapi Ved sepsis eller septisk shock anvendes isoton NaCl (0,9 %) som infusionsvæske. Ved hyponatriæmi og bevidsthedspåvirkning se** Giv ikke væsker som bliver hypotone efter indgift (Ringer, Na-K-Glukose eller Glukose), da risikoen for hjerneødem øges. Smertebehandling: paracetamol 1 g x 4 evt + morfin 10 mg […]
Professor Court Petersen kommenterer: Velskreven oversigtsartikel, der bør læses af alle, der har med sepsispatienter at gøre. Artiklen 'afliver' det noget forældede SIRS begreb. Andre 2013-artikler fra NEJM kan med stor fordel læses som supplement: 'Circulatory shock' N Engl J Med. 2013;369(18):1726-34 'Resuscitation fluids' N Engl J Med. 2013;369(13):1243-51 'Ventilator-induced lung injury' N Engl J Med. 2013;369(22):2126-36
Professor Niels Obel kommenterer: Denne artikel er tankevækkende - fordi vi nu igen står i en situation, hvor noget, vi mente var en 'sepsis-sandhed' fra et randomiseret trial, ser ud til at være forkert...
Nyt fra tidsskrifterne [+20]
Der er mere end 20 resultater, måske du vil se flere resultater her?
BMJ Open
5. november 2025
[…] Several antibiotic stewardship interventions have been proven effective and safe for reducing the high number of antibiotic prescriptions in late preterm and term neonates at risk of early-onset sepsis (EOS). For successful translation of EOS interventions to clinical practice, implementation strategies should be employed targeting stakeholders. The primary aim of this study is to assess the impact of implementing an antibiotic stewardship bundle, including the EOS calculator, […]
Critical Care Explorations
1. november 2025
[…] complement pathway is a key component of host defense against bacteremia and other infections. However, dysregulated activation can contribute to excessive inflammation and worse clinical outcomes during bacteremia and infectious syndromes such as sepsis. OBJECTIVES: We aim to identify variants in alternative pathway (AP) genes that influence the risk for bacteremia and sepsis. DESIGN, SETTING, AND PARTICIPANTS: We used summary statistics from a Veterans Affairs Million Veteran Program (MVP) […]
Clinical Infectious Diseases
31. oktober 2025
Clinical Infectious Diseases
31. oktober 2025
AImachine learningsepsis
BMC Infectious Diseases
28. oktober 2025
Critical Care Medicine
28. oktober 2025
[…] To explore and synthesize the adverse and transformative experiences of sepsis survivors and their caregivers, to generate novel, experience-based insights that inform recovery support and future care strategies. Data Sources: Five databases (MEDLINE, Embase, CINAHL, PsycINFO, Web of Science) were searched from 2000 to 2025. Study Selection: Eligible studies included qualitative or mixed-methods research reporting experiences of adult sepsis survivors and/or caregivers. Studies focusing solely […]
BMJ Open
25. oktober 2025
[…] develop and validate a predictive model for assessing in-hospital mortality in patients with intra-abdominal sepsis (IAS), a leading cause of sepsis. DesignSecondary analysis of two retrospective critical care databases. SettingData extracted from the Intensive Care Medicine Information Marketplace IV (MIMIC-IV) and the eICU Collaborative Research Database. ParticipantsPatients with IAS from MIMIC-IV (2008–2019; 1300 patients, 264 deaths) for model training and internal validation, and eICU […]
JAMA Network Open New Online
24. oktober 2025
Infectious Diseases
JAMA Network Open New Online
24. oktober 2025
This cohort study compares the performance of a large language model against manual medical record review for extracting presenting signs and symptoms data from hospital admission notes and uses these data to examine their associations with different sepsis syndromes and mortality.
BMC Infectious Diseases
24. oktober 2025
[…] is a life-threatening condition resulting from a dysregulated immune response to infection, often leading to organ failure and death. Early detection is vital, as delays significantly worsen outcomes. In recent years, the integration of artificial intelligence (AI), particularly Machine Learning (ML) and Deep Learning (DL), has shown great promise in enhancing early sepsis detection by identifying digital biomarkers from large-scale clinical datasets. This systematic review analyzes and synthesizes […]
Critical Care Medicine
24. oktober 2025
[…] To assess real-world RBC transfusion practices during early resuscitation in sepsis and evaluate their association with 60-day mortality. Design: Secondary analysis of a prospective, multicenter observational cohort (the Korean Sepsis Alliance cohort) from September 2019 to December 2022. Setting: Thirteen ICUs across South Korea. Patients: Adults (19 yr old or older) admitted to the ICU with sepsis were categorized into transfused and non-transfused groups based on whether they received RBC […]
BMJ Open
23. oktober 2025
[…] is defined as a dysregulated host response to infection, associated with high morbidity and mortality rates globally. Recent studies have indicated that increasing ketone levels may be beneficial for patients with sepsis. Existing research has established the feasibility, effectiveness and safety of the ketogenic diet in sepsis patients. This study aims to further clarify the organ-protective effects of a ketogenic diet in sepsis patients through a multicentre randomised controlled […]
Critical Care Explorations
18. oktober 2025
[…] Sepsis trials likely include patients who vary in response to therapeutic interventions. The optimal approach to identify such differences in treatment response remains unclear. Estimating individualized absolute risk differences (iARDs) to model treatment response at an individual patient level using supervised effect models applied to randomized trial data may be informative. We explored the relationship between two subgrouping approaches and a recently published iARD model for the effect of […]
BMC Infectious Diseases
17. oktober 2025
[…] whether the combination of these parameters further stratifies mortality risk in septic patients admitted to the intensive care unit (ICU). The aim of this study was to investigate the combined association of GV and SBPV with mortality in patients with sepsis. Methods The study utilized data from MIMIC-IV database. Patients with sepsis were stratified into four groups. The endpoint indicators of this study include ICU mortality, in-hospital mortality, 30-day mortality, 90-day mortality, 180-day […]
BMJ Open
16. oktober 2025
[…] outcomes from sepsis in children is a WHO Global Health Priority, yet mortality from sepsis remains high, particularly in low- and middle-income countries (LMICs). This database from children with community-acquired childhood sepsis in LMICs and some high-income countries will allow analysis of the burden of disease, including incidence, severity and outcomes. Understanding these aspects of sepsis care is fundamental for the design and conduct of future international interventional […]
BMJ Open
16. oktober 2025
[…] estimation is the basis for establishing the personal interventions in sepsis patients. Serum biomarkers are potential tools for predicting the outcomes of sepsis patients admitted to the intensive care unit (ICU). Here, we plan to perform a prospective study to investigate the prognostic value of serum biomarkers. We named this study Hospital Outcome of Host Heterogeneity, Organ dysfunction and Trajectory in sepsis (HOHHOT). Methods and analysisThis prospective cohort study is being […]
PLoS One Infectious Diseases
15. oktober 2025
[…] Florian Guillotin, Laetitia Aubert, Soraya Benguerfi, Reyes Munoz Calahorro, Alice Vennier, David Boutoille, Thomas Gastinne, Jean Reignier, Jean-Baptiste Lascarrou, Matilde Karakachoff, Emmanuel Canet Purpose Sepsis and septic shock in patients with neutropenia are associated with high mortality. We investigated the features and outcome predictors of neutropenic sepsis in the last decade. Methods Consecutive patients who were admitted to the intensive care unit (ICU) of a French university-affiliated […]
BMC Infectious Diseases
15. oktober 2025
[…] is a life-threatening disease and among the most common cause of death, which influence a series of following medical conditions. A comprehensive analysis of the cross-talks with temporary order of disease trajectory or trajectory led to cause of death following sepsis remains unclear. By using data from population-based UK Biobank, 8647 septic patients matching with 86386 controls without sepsis were included. Individuals were followed-up from 1 month after the index date until the end of 2019 with […]
BMJ Open
14. oktober 2025
[…] determinants of health (SDOH) factors are known to influence patient outcomes, but their effect on sepsis remains insufficiently studied. This research aims to investigate the relationship between SDOH factors and sepsis outcomes, highlighting opportunities to reduce health disparities and enhance patient care. DesignRetrospective study. SettingLevel I trauma centre in Baton Rouge, Louisiana, USA. ParticipantsPatients with sepsis aged 18–89 years. Patients discharged or transferred to […]
Aktuelle smitsomme sygdomme [+20]
Der er mere end 20 resultater, måske du vil se flere resultater her?
Medscape Infectious Diseases
24. oktober 2025
A database of death certificates shows that men, non-Hispanic Asians, and urban residents are hit hardest. Medscape Medical News
Medscape Infectious Diseases
30. september 2025
The term ‘viral sepsis’ has gained popularity since the COVID-19 pandemic, but whether it is clinically useful or risks misdiagnosis and treatment delay in severely ill patients has not been settled. Medscape Medical News
Medscape Infectious Diseases
16. september 2025
Patients with type 2 diabetes, particularly those aged 60 years or younger, have a notably greater risk for incident sepsis than those without the condition, a longitudinal study shows. Medscape Medical News
Medscape Infectious Diseases
14. juli 2025
Infants who develop sepsis or meningitis within their first week of life face a substantially increased risk for subsequent childhood epilepsy, a large population-based cohort study shows. Medscape News UK
Medscape Infectious Diseases
28. juni 2025
Delayed sepsis diagnosis remains a persistent risk in the NHS, with the health safety watchdog urging reforms to improve recognition, response, and care coordination. Medscape News UK
Medscape Infectious Diseases
5. april 2025
A ratio of serum aspartate aminotransferase to alanine aminotransferase levels serves as a strong prognostic tool to stratify the 30-day mortality risk in patients with sepsis-associated liver injury. Medscape News UK
Medscape Infectious Diseases
11. januar 2025
A slew of new sepsis studies may make you rethink your approach, says Dr Holley. Medscape Critical Care
Eurosurveillance latest updates
24. oktober 2025
[…] with emm1 type (odds ratio (OR) = 1.73; 95% confidence interval (CI): 1.13–2.67), having a sepsis without a known anatomic source (OR = 1.73; 95% CI: 1.11–2.73) and lower respiratory tract infections (OR = 4.14; 95% CI: 2.70–6.44). CONCLUSIONSurveillance of GAS and iGAS infections varied among the participating countries. We highlight the importance of including emm typing and analysis of clinical data in iGAS surveillance and having international collaboration for effective response to future […]
Medscape Infectious Diseases
21. august 2025
Adults with hidradenitis suppurativa treated with adalimumab have a greater risk for serious infections than those with psoriasis, particularly sepsis and urinary tract infections. Medscape Medical News
Eurosurveillance latest updates
31. maj 2025
[…] neonatal non-polio enterovirus infection, requiring hospital admission. Infants presented to different regional hospitals across Northern Ireland from late 2024 to early 2025. Three had neonatal meningitis and one showed rapid demise, leading to sepsis, multi-organ failure and death at day 6 of life. All infants were less than 18 days old at presentation, two were considered congenital infections, with one presenting symptoms at birth. All infants had detectable enterovirus RNA, typed as coxsackievirus […]
ProMED
16. april 2025
[…] is a bacteriumthat can nest in various raw foods and can cause infections withvariable symptoms: from mild forms such as gastroenteritis (with anaverage incubation of 24 hours) to serious and systemic forms such asmeningitis, meningoencephalitis and sepsis, with incubations of up to10-30 days. Inspections are also underway in other municipalities in the province,including Andria, to verify the safety of loose products on sale. TheASL Bt ensures maximum commitment and transparency in monitoring […]
ProMED
15. april 2025
[…] The disease appears suddenly with symptoms: high fever, severeheadache, vomiting, stiff neck, fatigue, possibly sore throat,hemorrhagic spots or patches, asterisk-shaped purpura or possiblyblisters. The disease often progresses rapidly causing meningitis,sepsis, which is more severe, causing multiple organ failure andpossibly death. Meningitis caused by meningococcal bacteria is dividedinto many forms, in which the simple form is similar to other forms ofmeningitis, which progresses and is cured within […]
ProMED
12. april 2025
[…] distribution in febrile patients in East Java, Indonesia Sani et al. IJID Regions 2025;14:100512
doi.org/10.1016/j.ijregi.2024.100512 Clinical, antibiotic resistance features, and treatment outcomes ofVietnamese patients with community-acquired
sepsis caused by_Klebsiella pneumoniae_ Giang et al. IJID Regions 2025;14:100505
doi.org/10.1016/j.ijregi.2024.100505 SARS-CoV-2 omicron XBB infections boost cross-variant neutralizingantibodies, potentially explaining the observed delay of the […]
ProMED
11. april 2025
[…] detection of viral co-infections,particularly in patients presenting with febrile syndromes. The diagnosis of meningitis for each patient was established using PCRtechniques (QIAstat-Dx Meningitis/Encephalitis panel). The suspicionof meningococcal sepsis was confirmed by a positive result with theBioFire FilmArray System Blood Culture Identification 2 (BCID2) panelon BD BACTEC blood culture vials after at least 4 h of incubation.This was followed by growth in culture media and […]
ProMED
8. april 2025
[…] _Streptococcus_, is responsible forstrep throat -- a far milder infection. Invasive streptococi cantrigger necrotizing fasciitis, a soft tissue infection also known asflesh-eating disease, or streptococcal toxic shock syndrome, an immunereaction akin to sepsis that can lead to organ failure. \'Within 24 to 48 hours, you could have very, very rapiddeterioration,\' said Dr. Victor Nizet, a professor of pediatrics atthe University of California, San Diego. Cases can transition from\'seeming like a routine […]
ProMED
3. april 2025
[…] or attemptingsurgical removal can be extremely dangerous. \'Each guinea worm maycarry 3 to 4 million larvae. If the worm is broken during extraction,it can release toxins and larvae into the body, leading toinflammation, secondary infections, or even sepsis,\' he explained.Other severe complications include joint immobility and abscessescaused by dead worms. To prevent guinea worm disease and other parasitic infections, Dr.Dung urged the public to practice safe food and hygiene habits. These include […]
ProMED
27. marts 2025
[…] died this year [2025]from complications related to severe enterovirus infections. According to a news release, the boy was a premature baby who washospitalized with respiratory distress syndrome after being born. InMarch [2025], he developed symptoms of sepsis including low bloodoxygen, bradycardia, hepatitis, and thrombocytopenia, and he died on17 Mar 2025. CDC physician Lin Yung-ching said at a press conference that the boytested positive for enterovirus and was diagnosed with enterovirusinfection with […]
ProMED
25. marts 2025
[…] in Viet Nam. _S. suis_ is a common gram-positive bacterium found in pigs, which cancause severe infections in humans; ≈90% of human cases are reportedfrom Asia. Case-fatality rates range from 3% to 7% but may reach≈60% among patients with severe sepsis, as observed in a largeoutbreak in Sichuan, China, in 2005. Studies have identifiedoccupational exposure to pigs and consumption of specific traditionalpork dishes as key risk factors for contracting _S. suis_ infection.Effective control of diseases […]