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American Journal of Tropical Medicine and Hygiene, 5.09.2024
Tilføjet 5.09.2024
Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 111 Issue: 3 Pages: 622-626
Læs mere Tjek på PubMedSarunya Maneerattanasak, Thundon Ngamprasertchai, Yin May Tun, Narisa Ruenroengbun, Prasert Auewarakul, Kobporn Boonnak
International Journal of Infectious Diseases, 29.08.2024
Tilføjet 29.08.2024
In Asia, dengue virus (DENV), Zika virus (ZIKV), and chikungunya virus (CHIKV) infections pose significant public health threats, which could result in substantially increased morbidity and mortality rates. These viruses, collectively known as arboviruses, share similarities in their epidemiology, transmission, and clinical manifestations. They often cause mild, subtle, or nonspecific clinical symptoms, while also potentially leading to severe and life-threatening complications [1]. Their rapid transmission is primarily facilitated through mosquito bites, notably by Aedes aegypti and Ae.
Læs mere Tjek på PubMedKieran S. O’Brien, Ahmed M. Arzika, Abdou Amza, Ramatou Maliki, Bawa Aichatou, Ismael Mamane Bello, Diallo Beidi, Nasser Galo, Naser Harouna, Alio M. Karamba, Sani Mahamadou, Moustapha Abarchi, Almou Ibrahim, Elodie Lebas, Brittany Peterson, Zijun Liu, Victoria Le, Emily Colby, Thuy Doan, Jeremy D. Keenan, Catherine E. Oldenburg, Travis C. Porco, Benjamin F. Arnold, and Thomas M. Lietmanthe AVENIR study group*From the Francis I. Proctor Foundation (K.S.O., E.L., B.P., Z.L., V.L., E.C., T.D., J.D.K., C.E.O., T.C.P., B.F.A., T.M.L.), the Departments of Ophthalmology (K.S.O., T.D., J.D.K., C.E.O., T.C.P., B.F.A., T.M.L.) and Epidemiology and Biostatistics (K.S.O., C.E.O., T.C.P., T.M.L.), and the Institute for Global Health Sciences (K.S.O., C.E.O., B.F.A., T.M.L.), University of California, San Francisco, San Francisco; and Centre de Recherche et Interventions en Santé Publique, Birni N’Gaoure (A.M.A., R.M., B.A., I.M.B., D.B., N.G., N.H., A.M.K., S.M., M.A.), and Programme Nationale de Santé Oculaire, Niamey (A.A., A.I.) — both in Niger.
New England Journal of Medicine, 22.08.2024
Tilføjet 22.08.2024
New England Journal of Medicine, Volume 391, Issue 8, Page 699-709, August 22/29, 2024.
Læs mere Tjek på PubMedWenlin RenChonglei FuYu ZhangXiaohui JuXi JiangJingwei SongMingli GongZhuoyang LiWenchun FanJun YaoQiang DingaCenter for Infection Biology, School of Medicine, Tsinghua University, Beijing 100084, ChinabState Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, McGovern Institute for Brain Research, School of Life Sciences, Tsinghua University, Beijing 100084, ChinacShanxi Medical University-Tsinghua Collaborative Innovation Center for Frontier Medicine, Shanxi Medical University, Taiyuan 030001, ChinadSchool of Management, Shanxi Medical University, Taiyuan 030001, ChinaeLife Science Institute, Zhejiang University, Hangzhou 31008, China
Proceedings of the National Academy of Sciences, 21.08.2024
Tilføjet 21.08.2024
Proceedings of the National Academy of Sciences, Volume 121, Issue 34, August 2024.
Læs mere Tjek på PubMedYang Shi Zihan Wang Jingjing Xu Wenxia Niu Yubin Wu Huiyu Guo Jinmiao Shi Zonglin Li Baorong Fu Yunda Hong Zikang Wang Wenjie Guo Dabing Chen Xingling Li Qian Li Shaojuan Wang Jiahua Gao Aling Sun Yaosheng Xiao Jiali Cao Lijuan Fu Yangtao Wu Tianying Zhang Ningshao Xia Quan Yuan a State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, School of Public Health & School of Life Sciences, Xiamen University, Xiamen, People’s Republic of Chinab National Institute of Diagnostics and Vaccine Development in Infectious Diseases, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostic, NMPA Key Laboratory for Research and Evaluation of Infectious Disease Diagnostic Technology, Xiamen University, Xiamen, People’s Republic of Chinac Department of Infectious Disease, Xiang’an Hospital of Xiamen University, Xiamen University, Xiamen, People’s Republic of Chinad Department of Clinical Laboratory, Women and Children’s Hospital, School of Medicine, Xiamen University, Xiamen, People’s Republic of China
Emerg Microbes Infect, 10.08.2024
Tilføjet 10.08.2024
The Lancet Infectious Diseases
Lancet Infectious Diseases, 9.08.2024
Tilføjet 9.08.2024
Arboviral infections have hit South America heavily in the past decade, with the epidemic of Zika virus in 2015–16, and recurrent outbreaks of chikungunya and dengue, the latter of which is affecting Brazil with a particularly high number of cases this year. In addition, the region is now facing the re-emergence of another little-known arbovirus, Oropouche virus, on an unprecedented scale.
Læs mere Tjek på PubMedJournal of Infectious Diseases, 31.07.2024
Tilføjet 31.07.2024
Abstract The Zika virus (ZIKV) epidemic in Latin America (2015-2016) has primarily been studied in urban centers, with less understanding of its impact on smaller rural communities. To address this gap, we analyzed ZIKV sero-epidemiology in six rural Ecuadorian communities (2018-2019) with varying access to a commercial hub. Seroprevalence ranged from 19% to 54% measured by NS1 blockade of binding ELISA. We observed a decline in ZIKV seroprevalence between 2018 and 2019 that was greater among younger populations, suggesting that the attack rates in the 2015-16 epidemic were significantly higher than our 2018 observations. These data indicate that the 2015-16 epidemic included significant transmission in rural and more remote settings. Our observations of high seroprevalence in our area of study highlights the importance of surveillance and research in rural areas lacking robust health systems to manage future Zika outbreaks and vaccine initiatives.
Læs mere Tjek på PubMedLeïla Lefèvre, Christophe Vincent-Titeca, Clémence Garcia, Laura Temime, Kévin Jean
International Journal of Infectious Diseases, 24.07.2024
Tilføjet 24.07.2024
The Ile-de-France Region (IDFR), which is set to host the Paris 2024 Olympics, is experiencing a concerning rise in imported cases of chikungunya, Zika, and dengue arboviral diseases [1]. The escalating presence of the Aedes albopictus mosquito, a competent vector for these diseases in temperate climates, is a significant threat [1]. The first dengue outbreak in the IDFR last fall underscored the local vulnerability to this risk [1].
Læs mere Tjek på PubMedJournal of the American Medical Association, 23.07.2024
Tilføjet 23.07.2024
Individuals with a previous infection with Zika virus may be more vulnerable to symptomatic infections of certain types of dengue virus, according to a cohort study of 3412 children aged 2 to 17 years old in Nicaragua.
Læs mere Tjek på PubMedCabada, M. M., Aguilar, P. V., Rodas, J. D., Hidalgo, M., Mozo, K., Gonzalez-Diaz, E. S., Jimenez-Coello, M., Diaz, F. J., Dacso, M. M., Ortega-Pacheco, A., Arboleda, M., Walker, D. H., Weaver, S. C., Melby, P. C.
BMJ Open, 23.07.2024
Tilføjet 23.07.2024
IntroductionAcute undifferentiated febrile illnesses (AUFIs) impose a large burden in the tropics. Understanding of AUFI’s epidemiology is limited. Insufficient diagnostic capacity hinders the detection of outbreaks. The lack of interconnection in healthcare systems hinders timely response. We describe a protocol to study the epidemiology and aetiologies of AUFI and pathogen discovery in strategic areas of Latin America (LA). Methods and analysisGlobal Infectious Diseases Network investigators comprising institutions in Colombia, Dominican Republic, México, Perú and the USA, developed a common cohort study protocol. The primary objective is to determine the aetiologies of AUFI at healthcare facilities in high-risk areas. Data collection and laboratory testing for viral, bacterial and parasitic agents are performed in rural and urban healthcare facilities and partner laboratories. Centralised laboratory and data management cores deploy diagnostic tests and data management tools. Subjects >6 years with fever for
Læs mere Tjek på PubMedGarnica, Marcia; Ramos, Jessica Fernandes; Machado, Clarisse Martins
Current Opinion in Infectious Diseases, 29.06.2024
Tilføjet 29.06.2024
Purpose of review Arbovirus infections are a challenge for immunocompromised hosts who travel to or live in endemic regions or who receive organs or tissues from donors who travel or live in such areas. This review addresses Dengue (DENV), Chikungunya (CHIKV), and Zika (ZIKV) infections in hematological patients, hematopoietic cell or solid organ transplant recipients, and people with HIV (PWH). Recent findings Transmission is mainly due through Aedes mosquito bite. DENV and ZIKV may also be transmitted through blood, tissues or donor grafts. Clinical manifestations are quite similar and diagnosis requires laboratory confirmation to provide appropriate management. The best diagnostic method is PCR since serology may present false negative results in immunocompromised patients, or cross-reactivity as in the case of DENV and ZIKV. There is no specific treatment for any of these infections. Summary Educational and preventive measures are the best strategy: vector control, knowledge of the vector\'s habits, protection against mosquito bites, avoiding travel to endemic areas or with a current epidemic, and avoiding nonvector transmission according to local recommendations for donor deferral. Vaccination, currently only available for DENV, has not yet been studied in immunocompromised patients and is not currently recommended.
Læs mere Tjek på PubMedBiao Hu, Jianping Chen, Zongtao Sun
Trends in Microbiology, 9.06.2024
Tilføjet 9.06.2024
The transmission of flaviviruses, such as dengue virus (DENV) and Zika virus (ZIKV), poses a significant threat to global public health. Zhang et al. recently showed that Rosenbergiella sp. YN46 (Rosenbergiella_YN46), a bacterium from the mosquito gut, inhibits flavivirus transmission and thus offers a potential biocontrol strategy with broad public health implications.
Læs mere Tjek på PubMedAmerican Journal of Tropical Medicine and Hygiene, 5.06.2024
Tilføjet 5.06.2024
Journal Name: The American Journal of Tropical Medicine and Hygiene Volume: 110 Issue: 6 Pages: 1178-1179
Læs mere Tjek på PubMedYongkang ChenYuan LiLu LuPeng Zou1Shanghai Public Health Clinical Center, Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Fudan University, Shanghai, ChinaMiguel Angel Martinez
Antimicrobial Agents And Chemotherapy, 30.05.2024
Tilføjet 30.05.2024
Abdoul-Aziz Maiga, Aboubacar Sombié, Nicolas Zanré, Félix Yaméogo, Souleymane Iro, Jean Testa, Antoine Sanon, Ousmane Koita, Hirotaka Kanuka, Philip J. McCall, David Weetman, Athanase Badolo
PLoS One Infectious Diseases, 30.05.2024
Tilføjet 30.05.2024
by Abdoul-Aziz Maiga, Aboubacar Sombié, Nicolas Zanré, Félix Yaméogo, Souleymane Iro, Jean Testa, Antoine Sanon, Ousmane Koita, Hirotaka Kanuka, Philip J. McCall, David Weetman, Athanase Badolo Background Ae. aegypti is the vector of important μ arboviruses, including dengue, Zika, chikungunya and yellow fever. Despite not being specifically targeted by insecticide-based control programs in West Africa, resistance to insecticides in Ae. aegypti has been reported in countries within this region. In this study, we investigated the status and mechanisms of Ae. aegypti resistance in Niamey, the capital of Niger. This research aims to provide baseline data necessary for arbovirus outbreak prevention and preparedness in the country. Methods Ovitraps were used to collect Ae. aegypti eggs, which were subsequently hatched in the insectary for bioassay tests. The hatched larvae were then reared to 3–5-day-old adults for WHO tube and CDC bottle bioassays, including synergist tests. The kdr mutations F1534C, V1016I, and V410L were genotyped using allele-specific PCR and TaqMan qPCR methods. Results Ae. aegypti from Niamey exhibited moderate resistance to pyrethroids but susceptibility to organophosphates and carbamates. The kdr mutations, F1534C, V1016I and V410L were detected with the resistant tri-locus haplotype 1534C+1016L+410L associated with both permethrin and deltamethrin resistance. Whereas the homozygote tri-locus resistant genotype 1534CC+1016LL+410LL was linked only to permethrin resistance. The involvement of oxidase and esterase enzymes in resistance mechanisms was suggested by partial restoration of mosquitoes’ susceptibility to pyrethroids in synergist bioassays. Conclusion This study is the first report of Ae. aegypti resistance to pyrethroid insecticides in Niamey. The resistance is underpinned by target site mutations and potentially involves metabolic enzymes. The observed resistance to pyrethroids coupled with susceptibility to other insecticides, provides data to support evidence-based decision-making for Ae. aegypti control in Niger.
Læs mere Tjek på PubMedCarla Bianca Luena VictorioArun GanasarajahWisna NoveraJoanne OngRasha MsallamAnn-Marie ChackoLaboratory for Translational and Molecular Imaging (LTMI), Cancer and Stem Cell Biology Programme, Duke-NUS Medical School, Singapore, Singapore
Emerg Microbes Infect, 29.05.2024
Tilføjet 29.05.2024
Priscila M. S. CastanhaPatrick J. McEnaneyYongseok ParkAnthea BouwerElton J. F. ChavesRoberto D. LinsNicholas G. PaciaroniPaige DicksonGraham CarlsonMarli T. CordeiroTereza MagalhaesJodi CraigoErnesto T. A. MarquesThomas KodadekDonald S. BurkeaDepartment of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261bDepartment of Chemistry, The Herbert Wertheim University of Florida Scripps Institute for Biomedical Innovation and Technology, Jupiter, FL 33458cDepartment of Biostatistics, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261dDepartment of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15219eDepartment of Virology, Aggeu Magalhaes Institute, Oswaldo Cruz Foundation, Cidade Universitearia, Recife, Pernambuco 50740-465, BrazilfDeluge Biotechnologies, Jupiter, FL 33458gDepartment of Entomology, Texas A&M University, College Station, TX 77843hDepartment of Preventive and Social Medicine, School of Medicine, Universidade Federal da Bahia, Bahia 40026-010, BraziliDepartment of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261
Proceedings of the National Academy of Sciences, 23.05.2024
Tilføjet 23.05.2024
Proceedings of the National Academy of Sciences, Volume 121, Issue 21, May 2024.
Læs mere Tjek på PubMed