Søgning på udtrykket 'pep' giver 43 resultater


Dokumenter [1] Sider [2] Kalender [1] Nyt fra tidsskrifterne [+20] Aktuelle smitsomme sygdomme [19]

Dokumenter [1]

Version: 3. Endelig guideline: 01.09.2020. Guideline skal revideres senest: 01.09.2023 Arbejdsgruppens medlemmer: Peer Brehm Christensen, Christian Erikstrup, Jan Gerstoft, Terese Katzenstein, Alex Laursen, Suzanne Lunding, Birgitte Mørn og Nina Weis.

Sider [2]

…t, Jens Lundgren, Alex Laursen, Niels Obel, Olav Larsen, Gitte Kronborg, Ann-Brit Eg Hansen Antiviral behandling af hiv smittede personer, Fertilitetsbehandling ved HIV og hepatitis B og C, HIV behandling af gravide, HIV post exposure profylakse (PEP), Pre-exposure profylakse mod HIV (PrEP), Borrelia: Anne-Mette Lebech, Sigurdur Skarphedinsson Borrelia klaringsrapport, COVID-19: Marie Helleberg/Jens Lundgren, Lothar Wiese, Michael Dalager-Pedersen, Merete Storgaar…

…fected Host: Epidemiology and Pathogenesis in the Antiretroviral Era Curr HIV/AIDS Rep. 2015; 12: 6?15. HIV - persistence on ART & cure research:. Margolis et al: Latency reversal and viral clearance to cure HIV-1. Science. 2016; 253: aaf6517. PREP og PEP:. Fonner et al. Effectiveness and safety of oral HIV preexposure prophylaxis for all populations: AIDS 2016 Jul 31;30(12):1973-83. Rodger et al. Sexual Activity Without Condoms and Risk of HIV Transmission in Serodifferent Couples When the HIV-Positive…


Kalender [1]

25. november 2019, Auditorium 3 og 4, Hvidovre Hospital

Nyt fra tidsskrifterne [+20]

Der er mere end 20 resultater, måske du vil se flere resultater her?
Proceedings of the National Academy of Sciences
17.01.2023
Proceedings of the National Academy of Sciences, Volume 120, Issue 4, January 2023.
Science Advances
11.01.2023
Science Advances, Volume 9, Issue 2, January 2023.
Proceedings of the National Academy of Sciences
9.01.2023
Proceedings of the National Academy of Sciences, Volume 120, Issue 3, January 2023.
Proceedings of the National Academy of Sciences
9.01.2023
Proceedings of the National Academy of Sciences, Volume 120, Issue 3, January 2023.
American Journal of Respiratory and Critical Care Medicine
15.12.2022
American Journal of Respiratory and Critical Care Medicine, Volume 206, Issue 12, Page 1508-1521, December 15, 2022.
Proceedings of the National Academy of Sciences: Immunology and Inflammation
29.11.2022
Proceedings of the National Academy of Sciences, Volume 119, Issue 49, December 2022.
Lancet
5.11.2022
H pylori eradication protects against aspirin-associated peptic ulcer bleeding, but this might not be sustained in the long term.
Frontiers in Immunology
26.10.2022
…an off the shelf immunotherapy. Here, we developed a PLGA-based nanoparticle vaccine that contains both the immunogenic cancer germline antigen NY-ESO-1 and an α-GalCer analog IMM60, as a novel iNKT cell agonist and dendritic cell transactivator. Three peptide sequences (85-111, 117-143, and 157-165) derived from immunodominant regions of NY-ESO-1 were selected. These peptides have a wide HLA coverage and were efficiently processed and presented by dendritic cells via various HLA subtypes. Co-delivery of…
Frontiers in Immunology
26.10.2022
…them. This cytotoxic response is supposed to be limited to infected cells to avoid killing of healthy cells. To enable this, CD8+ T cells have T Cell Receptors (TCRs) which should discriminate between self and non-self through the recognition of antigenic peptides bound to Human Leukocyte Antigen class I (HLA-I) complexes”i.e., HLA-I immunopeptidomes”of patrolled cells. The majority of these antigenic peptides are produced by proteasomes through either peptide hydrolysis or peptide splicing. Proteasome-…
Frontiers in Immunology
26.10.2022
Modern vaccine designs and studies of human leukocyte antigen (HLA)-mediated immune responses rely heavily on the knowledge of HLA allele-specific binding motifs and computational prediction of HLA-peptide binding affinity. Breakthroughs in HLA peptidomics have considerably expanded the databases of natural HLA ligands and enabled detailed characterizations of HLA-peptide binding specificity. However, cautions must be made when analyzing HLA peptidomics data because identified peptides may be contaminants i…
Frontiers in Immunology
26.10.2022
Peptide-loaded Major Histocompatibility Complex (pMHC) class I molecules can be expressed in a single chain trimeric (SCT) format, composed of a specific peptide fused to the light chain beta-2 microglobulin (β2m) and MHC class I heavy chain (HC) by flexible linker peptides. pMHC SCTs have been used as effective molecular tools to investigate cellular immunity and represent a promising vaccine platform technology, due to their intracellular folding and assembly which is apparently independent of host cell …
Critical Care Medicine
26.10.2022
Objectives: . . Respiratory failure is a lethal complication of COVID-19 that has remained resistant to drug therapy. Vasoactive intestinal peptide (VIP) is shown in nonclinical studies to upregulate surfactant production, inhibit cytokine synthesis, prevent cytopathy, and block replication of the severe acute respiratory syndrome coronavirus 2 virus in pulmonary cells. The study aims to determine whether Aviptadil (synthetic VIP) can improve survival and recovery in patients with COVID-19 respiratory fai…
Frontiers in Immunology
26.10.2022
Dendritic cells (DCs) are professional antigen-presenting cells that can recognize, capture, and process antigens. Fusing molecules targeting DCs with antigens can effectively improve the efficiency with which antigens are recognized and captured by DCs. This targeting strategy can be used for vaccine development to effectively improve the efficiency of antigen recognition and capture by DCs. The targeting sequence of porcine cytotoxic T-lymphocyte associated protein 4 (CTLA4), which binds porcine DCs, was …
AIDS
26.10.2022
…g antigen-specific T cell receptor (TCR) engineered T cells which recognize the specific antigen artificially may have tremendous potential in anti-MTB/HIV coinfection. We have previously successfully identified a MTB Ag85B199–207 and HIV-1 Env120–128 peptide-bispecific TCR screened out from peripheral blood mononuclear cells of a HLA-A∗0201+ healthy individual and have further studied that how residues on the predicted complementarity determining region (CDR) 3 of the β chain contribute to the bispe…
Frontiers in Immunology
26.10.2022
Tapasin, a component of the major histocompatibility complex (MHC) I peptide loading complex, edits the repertoire of peptides that is presented at the cell surface by MHC I and thereby plays a key role in shaping the hierarchy of CD8+ T-cell responses to tumors and pathogens. We have developed a system that allows us to tune the level of tapasin expression and independently regulate the expression of competing peptides of different off-rates. By quantifying the relative surface expression of peptides prese…
Frontiers in Immunology
26.10.2022
…t is not well understood. Previous studies indicated that the induction of FVIII inhibitors requires cognate interactions between FVIII-specific B cells and FVIII-specific CD4+ T cells in germinal center reactions. In this study, we investigated the FVIII peptide repertoire presented by antigen-presenting cells (APCs) under different microenvironment conditions that are expected to alter the uptake of FVIII by APCs. The aim of this study was to better understand the association between different microenviro…

Aktuelle smitsomme sygdomme [19]

Morbidity and Mortality Weekly Report (MMWR)
14.07.2022
This report describes HIV testing among children and adolescents in PEPFAR-supported countries during the COVID-19 pandemic.
ProMED
21.04.2022
Botulism -- United States
Morbidity and Mortality Weekly Report (MMWR)
24.03.2022
This report describes programmatic gains of HIV treatment during the pandemic.
Morbidity and Mortality Weekly Report (MMWR)
24.11.2021
This report describes early sexual debut and associated risks factors among adolescent girls in nine PEPFAR countries.
ProMED
21.07.2021
Other Plant Disease -- RussiaA 20-ton consignment of Uzbek fresh tomatoes arrived in the Irkutsk region [Russia]. Rosselkhoznadzor [Federal Service for Veterinary and Phytosanitary Surveillance] sent samples for examination. Virological results revealed _Pepino mosaic virus_ by PCR method. The test confirms the presence of a dangerous virus in the product. The virus was detected for the 1st time in Irkutsk region. Currently, there is no means of combating the disease. Preventive measures should be observed …
ProMED
1.07.2021
Other Plant Disease -- New ZealandNew Zealand tomato exports to six countries have been stopped, after the _Pepino mosaic virus_ (PepMV) was discovered on crops. The Ministry for Primary Industries (MPI) has notified Australia, Japan, Thailand, Fiji, Tonga, and New Caledonia, because these countries consider PepMV a quarantine risk. The virus was first detected in an Auckland glasshouse and has subsequently been found in tomato production facilities in the wider region. The premises where PepMV has been fou…
Morbidity and Mortality Weekly Report (MMWR)
27.05.2021
This report describes the impact of COVID-19 on HIV viral load testing in PEPFAR-supported countries.
ProMED
13.04.2021
Other Plant Disease -- SerbiaDuring a survey on tomato viruses conducted in Serbia, virus-like symptoms were observed in July 2019 in tomato plants (_Solanum lycopersicum_) grown in 2 separate plastic tunnels in Jablanica district. Affected plants showed yellow angular spots on the leaves accompanied by necrosis and distortion, as well as fruit discoloration. In these 2 tomato crops, disease incidence was estimated at 80%. Laboratory analysis (serological, molecular and biological tests) confirmed the pres…
Morbidity and Mortality Weekly Report (MMWR)
3.12.2020
This report describes sex differences in human immunodeficiency virus testing in sub-Saharan African countries.
Morbidity and Mortality Weekly Report (MMWR)
27.02.2020
When taken daily, preexposure prophylaxis (PrEP) reduces the risk of acquiring human immunodeficiency virus (HIV). PrEP is an important tool for preventing HIV among persons at substantial risk for HIV infection, including female sex workers, men who have sex with men, transgender women, and persons who inject drugs.
Morbidity and Mortality Weekly Report (MMWR)
27.11.2019
Human immunodeficiency virus (HIV) case-based surveillance continuously and systematically monitors HIV-positive patients throughout their clinical care until death.
Statens Serum Institut
14.12.2017
WHO har 1/12-2017 i en rapport fra Strategic Advisory Group of Experts on Immunization, SAGE, udgivet nye retningslinjer på baggrund af ny evidens om brugen af rabiesvacciner og rabies-immunglobulin (RIG).
Morbidity and Mortality Weekly Report (MMWR)
27.01.2023
This report describes an increase in people with HIV infection receiving PEPFAR-supported antiretroviral therapy in Uganda.
Morbidity and Mortality Weekly Report (MMWR)
14.07.2022
This report describes HIV testing among children and adolescents in PEPFAR-supported countries during the COVID-19 pandemic.
Morbidity and Mortality Weekly Report (MMWR)
24.11.2021
This report describes early sexual debut and associated risks factors among adolescent girls in nine PEPFAR countries.
ProMED
18.07.2021
Rabies -- United StatesA trip to a theme park now has 2 guests having to undergo [preventative] treatment for rabies. The Hampton-Peninsula Health District has alerted guests a rabid fox attacked 2 people at Busch Gardens, Williamsburg [Virginia], WTKR reported. A boy was bitten on 5 Jul 2021 by the fox and had to have 4 injections of rabies treatment. [Post Exposure Prophylaxis or PEP - Mod.TG] WTKR reported. He is OK. A man was also exposed to the fox. The fox was captured and died shortly after, WAVY
ProMED
1.07.2021
Other Plant Disease -- New ZealandNew Zealand tomato exports to six countries have been stopped, after the _Pepino mosaic virus_ (PepMV) was discovered on crops. The Ministry for Primary Industries (MPI) has notified Australia, Japan, Thailand, Fiji, Tonga, and New Caledonia, because these countries consider PepMV a quarantine risk. The virus was first detected in an Auckland glasshouse and has subsequently been found in tomato production facilities in the wider region. The premises where PepMV has been fou…
Morbidity and Mortality Weekly Report (MMWR)
27.05.2021
This report describes the impact of COVID-19 on HIV viral load testing in PEPFAR-supported countries.
ProMED
26.04.2021
Rabies -- PakistanA man from the city of Thatta in Sindh province, Pakistan died from rabies after a dog bite due to the local hospital not having rabies post-exposure prophylaxis (PEP). The victim was reportedly attacked by a rabid dog around a week ago and suffered injuries on the head and torso. Relatives took him to the local civil hospital only to find anti-rabies vaccine was not available. Doctors there recommended the family take him to a private hospital; however, they could not afford the cost

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