Søgning
Søgning på udtrykket 'pep' giver 42 resultater
Dokumenter [1] Sider [1] Nyt fra tidsskrifterne [+20] Aktuelle smitsomme sygdomme [+20]
Dokumenter [1]
Version: 3.
Sider [1]
…fected Host: Epidemiology and Pathogenesis in the Antiretroviral Era Curr HIV/AIDS Rep. 2015; 12: 6?15. HIV - persistence on ART & cure research:. Margolis et al: Latency reversal and viral clearance to cure HIV-1. Science. 2016; 253: aaf6517. PREP og PEP:. Fonner et al. Effectiveness and safety of oral HIV preexposure prophylaxis for all populations: AIDS 2016 Jul 31;30(12):1973-83. Rodger et al.
Nyt fra tidsskrifterne [+20]
Der er mere end 20 resultater, måske du vil se flere resultater her?
BMC Infectious Diseases
8.04.2025
…n against SARS-CoV-2 are needed to reduce the risk of immune escape and provide broad and long-lasting cellular immunity. The objectives of the naNO-COVID trial were to evaluate the safety and immunogenicity of a CD8 + T cell, gold nanoparticle-based, peptide COVID-19 vaccine. . Methods.
Critical Care Explorations
2.04.2025
OBJECTIVES: . The incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) have therapeutic effects in diabetes mellitus. Prior clinical studies suggest incretins are prognostic of adverse outcomes in critical illness. We investigated whether incretin levels indicate disease severity and clinical outcomes in patients with acute respiratory failure, a common cause of critical illness. DESIGN: . Retrospective cohort study. SETTING: .
Retrovirology
1.04.2025
Despite recent partial waivers granted by PEPFAR, the 2025 suspension of PEPFAR funding jeopardizes HIV/AIDS care for 20.6 million people, including 550,000 children, and risks reversing decades of progress in.
Infection
26.03.2025
Frontiers in Immunology
24.03.2025
Recent discoveries have transformed our understanding of peptide binding in Major Histocompatibility Complex (MHC) molecules, showing that peptides, for some MHC class II alleles, can bind in a reverse orientation (C-terminus to N-terminus) and can still effectively activate CD4+ T cells. These finding challenges established concepts of immune recognition and suggests new pathways for therapeutic intervention, such as vaccine design.
Science Advances
20.03.2025
Science Advances, Volume 11, Issue 12, March 2025.
Journal of Infectious Diseases
18.03.2025
…mpirically tested the predictions on unknown antigens with an in vitro multiplex MHC binding analysis. Peripheral blood mononuclear cells from clinical Coccidioides infections, and endemic or nonendemic healthy controls were stimulated with the identified peptides and evaluated for immunologic memory responses.Results . A total of 108 Coccidioides peptides were identified by MHC class II binding.
Clinical Infectious Diseases
11.03.2025
Abstract . Doxy-PEP is used to prevent chlamydia, syphilis and gonorrhea infections in sexual and gender minority men and transgender women. We describe a systematic process for developing algorithms that allow for the identification of doxy-PEP prescriptions. Using an identified algorithm will allow for improved monitoring of implementation and effectiveness.
PLoS One Infectious Diseases
11.03.2025
by Liming Wang, Yuping Tang, Anne F. Buckley, Robert F. Spurney . Natriuretic peptides (NPs) bind to glomerular podocytes and attenuate glomerular injury. The beneficial effects of NPs are negatively regulated by the NP clearance receptor (NPRC), which is highly expressed in podocytes. To determine if inhibiting NPRC is podocyte protective, we examined the effects of deleting NPRC in both cultured podocytes and in vivo.
Trends in Microbiology
7.03.2025
…among microorganisms, many of which have developed protection mechanisms. While well-characterized protection mechanisms involve relatively large proteins – such as exporters or compound- or target-modifying enzymes – we discuss how small proteins and peptides can also confer protection. Recent technological advances have revealed the functional capacity and importance of the small proteome, as well as its potential for de novo evolution.
Science Advances
6.03.2025
Science Advances, Volume 11, Issue 10, March 2025.
Lancet Microbe
4.03.2025
Within hours of being sworn in as US President on Jan 20, 2025, Donald Trump signed an executive order withdrawing his country from WHO.
PLoS One Infectious Diseases
12.02.2025
…by Pratchaya Muangrod, Wiriya Charoenchokpanich, Sittiruk Roytrakul, Vilai Rungsardthong, Sawanya Charoenlappanit, Benjamaporn Wonganu, Lueacha Tabtimmai, Phumin Chamsodsai, Federico Casanova, Benjawan Thumthanaruk . The identification of multifunctional peptides derived from marine byproducts represents a significant challenge in the field. In Thailand, the fisheries industry exports salted jellyfish, which results in low-value byproducts primarily employed for animal feed.
PLoS One Infectious Diseases
12.02.2025
…s however have been shown to induce substantially stronger Ab responses than CCVs in Parkinson’s Disease, and so may be capable of overcoming IL-31 tolerance to effectively treat CP. In this report, WISIT vaccines presenting ten different IL-31-specific peptides were compared to CCVs presenting the same peptides. Multiple response parameters were assessed, including Ab titers induced, avidity of these Abs, and IL-31 signaling inhibition.
Science Advances
6.02.2025
Science Advances, Volume 11, Issue 6, February 2025.
Proceedings of the National Academy of Sciences
30.01.2025
Proceedings of the National Academy of Sciences, Volume 122, Issue 4, January 2025. SignificanceThe bacterial cell wall needs to be expanded for growth, and this process requires the cleavage of cell wall crosslinks. While cell wall hydrolase activity is essential for this expansion, excessive activity can compromise the cell wall and .
Proceedings of the National Academy of Sciences
30.01.2025
Proceedings of the National Academy of Sciences, Volume 122, Issue 4, January 2025. SignificanceDuring the recent COVID-19 pandemic, the pathogen SARS-CoV-2 continuously mutated to produce new strains, challenging the development of therapeutics. To develop a mutation-tolerant anti-infective drug, we focused on the fact that while .
PLoS One Infectious Diseases
24.01.2025
by Rui Mi, Xuejun Li, Yajie Li, Xingfan Du . Objective This study aimed to evaluate the positive effects on anti-oxidation, anti-inflammation, and microbial composition optimization of diabetic mice using tussah (Antheraea pernyi) silk fibroin peptides (TSFP), providing the theoretical foundation for making the use of silk resources of A. pernyi and incorporating as a supplement into the hypoglycemic foods. Method The animal model of diabetes was established successfully.
PLoS One Infectious Diseases
24.01.2025
…tance due to countless biological properties. Cordyceps militaris contains bioactive compounds with antioxidant, antimicrobial and anti-cancerous properties. This study was projected to analyze the potentials of biometabolites and to extract antimicrobial peptides and protein from the C. militaris. An in-vitro analysis of biometabolites and antimicrobial peptides was performed to investigate their pharmacological potentials followed by quantification and characterization of extracted protein.
Antimicrobial Agents And Chemotherapy
15.01.2025
Antimicrobial Agents and Chemotherapy, Ahead of Print.
Aktuelle smitsomme sygdomme [+20]
Der er mere end 20 resultater, måske du vil se flere resultater her?
Medscape Infectious Diseases
18.01.2025
Dr Jessica A. Penney and Sherry Chen at the Centers for Disease Control and Prevention provide guidance on doxy-PEP for STI prevention. . CDC Expert Commentary
Medscape Infectious Diseases
12.12.2024
Antimicrobial peptides have not typically lived up to their promise, especially when it comes to beating antibiotic resistance, but novel avenues could see them reach the clinic yet. . Medscape Medical News
Medscape Infectious Diseases
19.11.2024
Approximately 80% of patients who started STI-PEP via telehealth remained in HIV PrEP care after 3 months . Medscape Medical News
Medscape Infectious Diseases
25.06.2024
An antimicrobial peptide spray demonstrates promise in managing mild to moderate diabetic foot complications. . Medscape Diabetes & Endocrinology
ProMED
15.04.2025
…ratory failure can occur. - Mod.LL . ProMED map:. Lviv, Lviv Oblast, Ukraine:. promedmail.org/promed-post?place=8723651,9359] . [See Also:. Botulism - Ukraine (02): (DP). promedmail.org/post/20250324.8723118 . Botulism - Russia: (RO) canned peppers. promedmail.org/post/20250320.8723028 . Botulism - Ukraine: (LV) canned meat. promedmail.org/post/20250319.8722980 . Botulism - Uzbekistan: (BU) canned tomatoes, fatal. promedmail.org/post/20250210.8722012 .
ProMED
14.04.2025
… children with fatal KD across 5 decades, 10. from the United States and 10 from Japan, and were absent in 19 of 20. infant controls (P < .001). We also found that all 12 childrenwith. acute KD generated plasmablast(s) recognizing the previously reported. peptide antigen. Taken together, these results point to 1 predominant. causative agent of KD across many decades and geographic areas and. should direct future KD research studies.' . . The identity of this potential cause is yet unknown but the.
ProMED
11.04.2025
…ive treatment and supportive care, including. continuous fluid drainage and mechanical ventilation'. . 'Anthrax post-exposure prophylaxis and treatment . ---------------------------- . 'Antibiotics . Antibiotics can be used for post-exposure prophylaxis (PEP) to prevent. anthrax from developing in people who have been exposed but are not. symptomatic. All types of anthrax infection can be treated with. antibiotics. Two of the most common antibiotics given offer the same. protection against anthrax: .
ProMED
11.04.2025
…. public health concern in the Asia-Pacific Region. The disease is. predominantly transmitted by domestic dogs; it is almost invariably. fatal once clinical signs appear. Successful rabies control includes:. (i) prompt access to post-exposure prophylaxis (PEP) following an. exposure, including thorough wound washing, a series of rabies. vaccines, and in some cases, rabies immunoglobulin (RIG)/rabies. monoclonal antibodies (RmAbs); (ii) mass dog vaccination to prevent.
ProMED
8.04.2025
…y. vaccination of all domestic carnivores. Nevertheless, the incidence of. human and animal rabies cases remained steady with an average of 20. human deaths per year, and an average of 120 000 people are exposed to. rabies yearly and eventually go through PEP procedure'. (doi.org/10.1016/j.prevetmed.2018.07.011). . The following study, published in July 2024, aimed to assess the. knowledge, attitude, and practice (KAP) of Algerian university.
ProMED
3.04.2025
…tulism - USA (04): (TX) wound, injection drug related, 2020-21. promedmail.org/post/20220527.8703504 . Botulism - USA (03): (WA) probable case, home-canned food, fatal. promedmail.org/post/20220428.8702905 . Botulism - USA (02): jarred sweet peppers, risk, recall. promedmail.org/post/20220421.8702754 . . Note: This content and the data herein may not be copied, reproduced,. scraped, redistributed, reused, or repurposed alone or together with.
ProMED
30.03.2025
… territories. across the globe. Up to 95% of human deaths occur in Africa and Asia. where dog rabies is poorly controlled and disproportionately affects. poor rural communities where control programmes and access to. appropriate post-exposure prophylaxis (PEP) is limited or. non-existent. . 'Because rabies is under-reported, mis- and under-diagnosed, data on. human deaths, access to vaccines, and occurrence in animal populations. is limited. Currently, these data are more likely to indicate the.
ProMED
29.03.2025
… over 80 people have died from rabies after an exposure. during travel. Rabies is prevalent globally except in Antarctica. In. Africa, Asia, and specific areas of Central and South America, rabies. in dogs is still a major problem. Additionally, access to PEP may be. hard to get in those places. As a result, tens of thousands of people. die of the disease each year. . 'When traveling, it is important to keep your distance from wild and. unfamiliar animals, including dogs and cats.
ProMED
18.03.2025
…tulism - USA (04): (TX) wound, injection drug related, 2020-21. promedmail.org/post/20220527.8703504 . Botulism - USA (03): (WA) probable case, home-canned food, fatal. promedmail.org/post/20220428.8702905 . Botulism - USA (02): jarred sweet peppers, risk, recall. promedmail.org/post/20220421.8702754 . . Note: This content and the data herein may not be copied, reproduced,. scraped, redistributed, reused, or repurposed alone or together with.
ProMED
17.03.2025
… emphasise the establishment of dedicated centres at the. district level for treatment of dog-bite injuries given the fact that. rabies is fatal in 100 per cent of cases. . Deaths from the infection are preventable with prompt post-exposure. prophylaxis (PEP) by stopping the virus from reaching the central. nervous system. . Rabies can be completely prevented if the wound is immediately and. thoroughly flushed and washed with soap and flowing water, followed by.
ProMED
9.03.2025
…tulism - USA (04): (TX) wound, injection drug related, 2020-21. promedmail.org/post/20220527.8703504 . Botulism - USA (03): (WA) probable case, home-canned food, fatal. promedmail.org/post/20220428.8702905 . Botulism - USA (02): jarred sweet peppers, risk, recall. promedmail.org/post/20220421.8702754 . . Note: This content and the data herein may not be copied, reproduced,. scraped, redistributed, reused, or repurposed alone or together with.
ProMED
5.03.2025
…tulism - USA (04): (TX) wound, injection drug related, 2020-21. promedmail.org/post/20220527.8703504 . Botulism - USA (03): (WA) probable case, home-canned food, fatal. promedmail.org/post/20220428.8702905 . Botulism - USA (02): jarred sweet peppers, risk, recall. promedmail.org/post/20220421.8702754 . . Note: This content and the data herein may not be copied, reproduced,. scraped, redistributed, reused, or repurposed alone or together with.
ProMED
3.03.2025
…ed the prevalence of potentially pathogenic and. antimicrobial-resistant _E. coli_ in raw milk and dairy products from. Kafrelsheikh and Algarbia Governorates, Egypt. 210 samples including. raw buffalo milk, goat milk, Domiati cheese, Domiati cheese with. pepper, rayeb, and yogurt were analyzed. The prevalence of _E. coli_. was 26.2%, with the highest occurrence in buffalo milk (68.0%) and the. lowest in rayeb (7.5%). Based on ERIC-PCR, 84 non-clonal _E. coli_.
ProMED
27.02.2025
…condition such as diabetes (most. common risk factor), renal disease, cirrhosis, thalassemia, alcohol. dependence, immunosuppressive therapy, chronic obstructive lung. disease, cystic fibrosis, and excess kava consumption. Kava is an. herbal member of the pepper family that can be associated with chronic. liver disease. . Melioidosis may present at any age, but peaks in the fourth and fifth. decades of life, affecting men more than women. In addition, although.
ProMED
21.02.2025
…ns or symptoms of illness (cough, sore throat, headache, and. myalgia), which began 6 days after illness onset in cat 1A). The. household 1 members who received testing received a 10-day course of. twice-daily oral oseltamivir as postexposure prophylaxis (PEP) at the. time of testing; the dairy farmworker declined testing and PEP.††. Adolescent 1B reported a 'dry croupy' cough 6 days after onset of. illness in cat 1A that was attributed to severe allergies.
ProMED
21.02.2025
…idrug therapy] alone have. proven insufficient to interrupt transmission. WHO recommends contact. tracing (household, neighbourhood, and social contacts), accompanied. by the administration of a single dose of rifampicin as post-exposure. prophylaxis (SDR-PEP)'. (www.who.int/news-room/fact-sheets/detail/leprosy). . 'If left untreated, advanced Hansen's disease can cause the. following: . - Paralysis and crippling of hands and feet . - Shortening of toes and fingers due to reabsorption .