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Søgning på udtrykket 'malaria' giver 45 resultater

Dokumenter [1] Sider [1] Kalender [2] Nyt fra tidsskrifterne [20] Aktuelle smitsomme sygdomme [20]

Dokumenter [1]

Guideline vedrørende diagnostik og behandling af malaria. Udarbejdet af Kim David, Carsten Schade Larsen, Peter Ellekvist, Signe Maj Sørensen og Lasse Vestergaard


Sider [1]

…stoft, Henrik Nielsen Influenza Inspektorordningen i Sundhedsstyrelsen Hanne Arildsen, Thomas Benfield Kronisk viral hepatitis Nina Weis, Peer B Christensen, Alex Lund Laursen Hepatitis A Hepatitis B og C guidelines Malaria Carsten Schade Larsen, Lasse Skafte Vestergaard, Peter Ellekvist, Signe Maj Sørensen og Kim David Malaria Meningitis og encephalitis Anne Mette Lebech, Christian Brandt, Lykke Larsen, Jacob Bodilsen, Lothar Wiese, Birgitte Rønde H…


Kalender [2]


Nyt fra tidsskrifterne [20]

Der er mere end 20 resultater, måske du vil se flere resultater her?
Current Opinion in Infectious Diseases
1.10.2021
Purpose of review Artemisinin-based combination therapies (ACTs) are globally the first-line treatment for uncomplicated falciparum malaria and new compounds will not be available within the next few years. Artemisinin-resistant Plasmodium falciparum emerged over a decade ago in the Greater Mekong Subregion (GMS) and, compounded by ACT partner drug resistance, has caused significant ACT treatment failure. This review provides an update on the epidemiology, and mechanisms of artemisinin resistance and appr…
Malaria Journal
22.09.2021
Abstract Background The FcγRs genotypes have been reported to play a key role in the defence against malaria parasites through both cellular and humoral immunity. This study aimed to investigate the possible correlation between FcγR (IIa, IIIa, and IIIb) genes polymorphism and the clinical outcome for anti‐malarial antibody response of Plasmodium falciparum infection among Saudi children. …
Trends in Parasitology
21.09.2021
In the early 2000s, artemisinin-based combination therapy (ACT) was introduced as first-line treatment for uncomplicated Plasmodium falciparum malaria in virtually all endemic countries. However, despite the well-known excellent tolerability of ACTs, hypersensitivity to artemisinin derivatives remains a repeatedly documented adverse drug reaction of still unknown frequency. The clinical features of an artemisinin-induced hypersensitivity reaction range from mild to life-threatening severity, and a significa…
Malaria Journal
20.09.2021
Abstract Background Venezuela accounted for 55% of the cases and 73% of the malaria deaths in the Americas in 2019. Bolivar state, in the southeast, contributes > 60% of the country's Plasmodium vivax and Plasmodium falciparum cases every year. This study describes the clinical–epidemiological characteristics of clinical malaria patients in this high-transmission area. M…
BMC Infectious Diseases
19.09.2021
…me countries such as the US, the UK, Italy and Belgium have reported high COVID-19 related deaths but low-and-middle-income countries have recorded fewer deaths despite having poor healthcare system. This study aimed to investigate the association between malaria prevalence and COVID-19 mortality. Methods An ecological study was conducted with data from 195 countries. Spearman’s correlation was used to test the associat…
Malaria Journal
17.09.2021
Abstract Background Despite significant strides made in reducing malaria morbidity and mortality in the Greater Mekong Subregion, malaria transmission continues amongst the most ‘hard-to-reach’, such as forest-goers and mobile and migrant populations, who face access obstacles to malaria diagnosis and treatment. As such, regional malaria elimination strategies endeavour to incorporate the private sector and local communities in improving s…
Malaria Journal
17.09.2021
Abstract Background A key step to advancing the goal of malaria elimination in Viet Nam by 2030 is focusing limited resources for treatment and prevention to groups most at risk for malaria transmission. Methods To better understand risk factors for malaria transmission in central Viet Nam, a survey of 1000 malaria positive cases and 1000 malaria negative co…
Malaria Journal
17.09.2021
Abstract Background Ethiopia embarked on combating malaria with an aim to eliminate malaria from low transmission districts by 2030. A continuous monitoring of malaria prevalence in areas under elimination settings is important to evaluate the status of malaria transmission and the effectiveness of the currently existing malaria intervention strategies. The aim of this study was to assess the prevalence of malaria and associated risk factors i…
Malaria Journal
17.09.2021
Abstract Background French Guiana (FG) is a French overseas territory where malaria is endemic. The current incidence rate is 0.74‰ inhabitants, and Plasmodium vivax is widely predominating even though Plasmodium falciparum is still present due to imported cases mainly from Africa. In FG, rapid diagnostic test (SD Malaria Ag P.f/Pan®) is based on the detection of pan-pLDH, PfHRP2, and PfHRP3 antigens, while in South America, the share of de…
Malaria Journal
16.09.2021
Abstract Background Malaria transmission in The Gambia decreased substantially over the last 20 years thanks to the scale-up of control interventions. However, malaria prevalence is still relatively high in eastern Gambia and represents both a health and a financial burden for households. This study aims to quantify the out-of-pocket costs and productivity losses of seeking malaria treatment at household level. …
American Journal of Tropical Medicine and Hygiene
15.09.2021
Journal Name: The American Journal of Tropical Medicine and HygieneVolume: 105Issue: 3Pages: 670-676
BMJ Open
13.09.2021
…s. Results Out of 1845 households visited, 21% (393 of 1845) reported an episode of fever. About 50% (195 of 393) of the fever cases had blood sample taken for testing by microscopy or Rapid Diagnostic Test, and 73.3% (143 of 195) were confirmed to have malaria. Of the 393 people with fever, 70% (271 of 393) reported taking an antimalarial and 24.0% (65 of 271) took antimalarial within 24 hours of the onset of illness. About 54% (145 of 271) of the antimalarials were obtained from health facilities. The …
Nature
13.09.2021
Nature Medicine, Published online: 13 September 2021; doi:10.1038/s41591-021-01492-6 Vaccines alones will not be sufficient for the eradication of malaria, which will also require investment in health professionals, better use of data, and universal access to quality health services.
Nature
13.09.2021
Nature Medicine, Published online: 13 September 2021; doi:10.1038/s41591-021-01470-y The PfSPZ Vaccine does not protect infants from infection with Plasmodium falciparum, the major cause of malaria.
Malaria Journal
10.09.2021
Abstract Background Malaria eradication requires a combined effort involving all available control tools, and these efforts would be complemented by an effective vaccine. The antigen targets of immune responses may show polymorphisms that can undermine their recognition by immune effectors and hence render vaccines based on antigens from a single parasite variant ineffective against other variants. This study compared the influence of allelic …
BMC Infectious Diseases
10.09.2021
Abstract Background Brucellosis is an important neglected bacterial zoonotic disease that has been affecting animals and humans for decades. Malaria has been considered major cause of illness in tropical areas, including Ethiopia. This study aimed to identify prevalence and risk factors of human brucellosis and malaria among patients with fever in malaria-endemic areas attending health institutes in Awra and Gulina district, Afar Region, Ethio…
Malaria Journal
9.09.2021
Abstract Background In many endemic areas, Plasmodium vivax malaria is predominantly a disease of young adults and children. International recommendations for radical cure recommend fixed target doses of 0.25 or 0.5 mg/kg/day of primaquine for 14 days in glucose-6-phosphate dehydrogenase normal patients of all ages. However, for many anti-malarial drugs, including primaquine, there is evidence that children have lower exposures than adults f…
BMC Infectious Diseases
9.09.2021
Abstract Background Malaria and schistosomiasis present considerable disease burden in tropical and sub-tropical areas and severity is worsened by co-infections in areas where both diseases are endemic. Although pathogenesis of these infections separately is well studied, there is limited information on the pathogenic disease mechanisms and clinical disease outcomes in co-infections. In this study, we investigated the prevalence of malaria and…
PLoS One Infectious Diseases
8.09.2021
…Background A DNA-prime/human adenovirus serotype 5 (HuAd5) boost vaccine encoding Plasmodium falciparum (Pf) circumsporozoite protein (PfCSP) and Pf apical membrane antigen-1 (PfAMA1), elicited protection in 4/15 (27%) of subjects against controlled human malaria infection (CHMI) that was statistically associated with CD8+ T cell responses. Subjects with high level pre-existing immunity to HuAd5 were not protected, suggesting an adverse effect on vaccine efficacy (VE). We replaced HuAd5 with chimpanzee aden…
Malaria Journal
8.09.2021
…Google were screened. A total of 90 publications were selected out of 1527. Besides, over 200 additional publications were consulted to collate information on anopheline breeding habitats and species distribution in urban settings. The study confirms high malaria transmission in rural compared to urban settings. The study also suggests that there had been an increase in malaria transmission in most cities after 2003, which could also be associated with an increase in sampling, resources and reporting. Speci…

Aktuelle smitsomme sygdomme [20]

Der er mere end 20 resultater, måske du vil se flere resultater her?
Medscape Infectious Diseases
17.09.2021
The drug, which was approved by the FDA last year, is an initial treatment of severe malaria in adults and children.
Medscape Infectious Diseases
31.08.2021
The study found the combination reduces the incidence of malaria by 62% against clinical malaria infection, 70% against severe malaria, and 73% against death from malaria compared with SMC alone.
ProMED
15.08.2021
Malaria -- Worldwide/UnknownBackgroundAdditional interventions are needed to reduce the morbidity and mortality caused by malaria. MethodsWe conducted a two-part, phase 1 clinical trial to assess the safety and pharmacokinetics of CIS43LS, an antimalarial monoclonal antibody with an extended half-life, and its efficacy against infection with _Plasmodium falciparum_. Part A of the trial assessed the safety, initial side-effect profile, and pharmacokinetics of CIS43LS in healthy adults who had never had malar…
Medscape Infectious Diseases
13.08.2021
The small clinical trial is the first to show an antibody capable of preventing malaria in people.
Medscape Infectious Diseases
6.08.2021
Study results suggest that public health needs to be factored into economic development plans.
ProMED
20.07.2021
Malaria -- YemenThousands of citizens have been infected with malaria since the beginning of this year [2021] in areas controlled by the ousted Hadi government in Taiz province, southwest Yemen. Health facilities in the province have recorded 4000 confirmed and suspected cases of malaria, a media source said, quoting an official in the malaria control program in the province. The official noted that the areas where malaria had spread significantly were on the west coast, west, and western
Statens Serum Institut
12.07.2021
En nyudviklet malariavaccine bliver nu for første gang undersøgt i mennesker.
ProMED
6.07.2021
Malaria -- ChinaBeginning in the 1950s, health authorities in China worked to locate and stop the spread of malaria by providing preventive antimalarial medicines for people at risk of the disease as well as treatment for those who had fallen ill. The country also made a major effort to reduce mosquito breeding grounds and stepped up the use of insecticide spraying in homes in some areas. In 1967, the Chinese Government launched the "523 Project" -- a nation-wide research programme aimed at finding new
ProMED
13.06.2021
Malaria -- PanamaThe national head of Epidemiology at the Ministry of Health [editor's note: Ministry of Health in Spanish is Ministerio de Salud (often abbreviated as MINSA)], Leonardo Labrador, mentioned that malaria cases showed an increase at the beginning of the year [2021]. However, at present, the situation is limited mainly to endemic areas, such as Guna Yala [Indigenous Region, northeast Atlantic coast], Darien [Province, eastern], and Eastern Panama [part of the province of Panama, which includes …
Medscape Infectious Diseases
5.05.2021
A report from the WHO reports incomplete success.
ProMED
24.04.2021
Malaria -- Worldwide/UnknownBackground: Stalled progress in controlling _Plasmodium falciparum_ malaria highlights the need for an effective and deployable vaccine. RTS,S/AS01, the most effective malaria vaccine candidate to date, demonstrated 55.8% (97.5% confidence interval [CI], 51-60) efficacy over 12 months in African children. Methods: We conducted a double-blind, randomised, controlled trial of a low-dose circumsporozoite protein-based vaccine, R21, with 2 different doses of adjuvant, Matrix-M(TM) (M…
Medscape Infectious Diseases
21.04.2021
Artemisinin resistance has long plagued the Mekong Delta, but the drug remains critical for treating malaria in Africa.
ProMED
17.04.2021
Malaria -- Worldwide/UnknownCitation: Uwimana A, Umulisa N, Venkatesan M, et al. Association of _Plasmodium falciparum kelch13_ R561H genotypes with delayed parasite clearance in Rwanda: an open-label, single-arm, multicentre, therapeutic efficacy study. Lancet. Epub 14 Apr 2021. Summary------Background: Partial artemisinin resistance is suspected if delayed parasite clearance (i.e., persistence of parasitaemia on day 3 after treatment initiation) is observed. Validated markers of artemisinin partial resis…
Morbidity and Mortality Weekly Report (MMWR)
18.03.2021
CDC summarizes malaria cases reported in the U.S. for 2017.
Statens Serum Institut
27.04.2020
Antallet af malaria sygdomstilfælde og dødsfald er halveret siden 2000. Men nu frygter WHO og Den Globale Fond til Bekæmpelse af HIV, Tuberkulose og Malaria store tilbageslag i kampen mod malaria set i lyset af den globale COVID-19-pandemi. De værste beregninger forudser en potentiel fordobling i antallet af malariatilfælde allerede i 2020.
Morbidity and Mortality Weekly Report (MMWR)
21.11.2019
The Food and Drug Administration approved tafenoquine for prophylaxis of malaria and antirelapse therapy.
Statens Serum Institut
13.11.2019
Michael Theisen fra Afdeling for Medfødte Sygdomme på SSI er blevet udnævnt til professor ved Københavns Universitet (KU).
Statens Serum Institut
4.10.2019
Statens Serum Institut (SSI) har sammen med et internationalt forskerkonsortium fået en stor fondsbevilling fra EDCTP. Pengene skal gå til at teste tre lovende malariavacciner i fire lande i Afrika.
Statens Serum Institut
26.07.2019
Multiresistente malariaparasitter har ifølge nyt studie spredt sig til flere områder i Sydøstasien. Multiresistent betyder dog ikke, at parasitterne er resistente overfor alle typer malariamedicin.
Morbidity and Mortality Weekly Report (MMWR)
16.05.2019
Malaria is endemic in many countries, and chemoprophylaxis is the best method of prevention.

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