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BMC Infectious Diseases
21.01.2025
. Abstract. Influenza-related acute lung injury is a life-threatening condition primarily caused by uncontrolled replication of the influenza virus and intense proinflammatory responses. Cereblon (CRBN) is a protein known for its role in the ubiquitin-proteasome system and as a target of the drug thalidomide. However, the function of CRBN in influenza virus infection remains poorly understood.
Journal of Medical Virology
17.01.2025
Journal of Medical Virology, Volume 97, Issue 1, January 2025.
Journal of Medical Virology
17.01.2025
Journal of Medical Virology, Volume 97, Issue 1, January 2025.
Emerg Microbes Infect
16.01.2025
Volume 14, Issue 1, December 2025 .
Emerg Microbes Infect
10.01.2025
Volume 14, Issue 1, December 2025 .
PLoS One Infectious Diseases
8.01.2025
…Metawee Thongdee, Somjit Chaiwattanarungruengpaisan, Natthaphat Ketchim, Nareerat Sangkachai, Nlin Arya, Wanna Sirimanapong, Witthawat Wiriyarat, Pilaipan Puthavathana, Weena Paungpin . Crocodilians are susceptible to a range of virus infection including influenza A virus (IAV). However, little is known about the ecology and epidemiology of IAV in crocodile species. This study aimed to investigate IAV infection in farmed Siamese crocodiles in central Thailand.
PLoS One Infectious Diseases
7.01.2025
by Kazi Mehedi Mohammad, Asma Akter Akhi, Md. Kamrujjaman . This research uses numerical simulations and mathematical theories to simulate and analyze the spread of the influenza virus. The existence, uniqueness, positivity, and boundedness of the solution are established. We investigate the fundamental reproduction number guaranteeing the asymptotic stability of equilibrium points that are endemic and disease-free. We also examine the qualitative behavior of the models.
New England Journal of Medicine
2.01.2025
New England Journal of Medicine, Ahead of Print.
New England Journal of Medicine
2.01.2025
New England Journal of Medicine, Ahead of Print.
Virulence
29.12.2024
Volume 16, Issue 1, December 2025 .
Science Advances
14.12.2024
Science Advances, Volume 10, Issue 50, December 2024.
Journal of Infectious Diseases
13.12.2024
Abstract . Background . The high-dose (HD) Fluzone influenza vaccine is currently recommended for individuals 65 and older, since it was shown in past studies to improve antibody responses and vaccine efficacy (VE) compared to a standard-dose (SD) formulation. Since influenza vaccines are frequently reformulated, monitoring any potential changes in VE is crucial. Traditional efficacy trials can be costly and time-consuming.
Emerg Microbes Infect
11.12.2024
Volume 14, Issue 1, December 2025 .
Emerg Microbes Infect
11.12.2024
Volume 14, Issue 1, December 2025 .
Lancet Microbe
10.12.2024
WBE affords a means to monitor circulating human and avian IAV strains and provide crucial genetic information. As such, WBE can provide rapid, cost-effective, year-round One Health surveillance to help control IAV epidemic and pandemic-related threats. However, optimisation of WBE protocols are necessary to ensure observed wastewater signals not only correlate with clinical case data, but yield information on the wider environmental pan-influenz-ome.
Virulence
2.12.2024
Volume 15, Issue 1, December 2024 .
Clinical Infectious Diseases
28.11.2024
…iral therapy as soon as possible for patients hospitalized with confirmed or suspected influenza.Methods . A multicenter US observational sentinel surveillance network prospectively enrolled adults (aged ≥18 years) hospitalized with laboratory-confirmed influenza at 24 hospitals during October 1, 2022–July 21, 2023.
BMJ Open
25.11.2024
. Introduction. Protecting non-native ethnic minority groups against cocirculation of influenza and COVID-19 is crucial, and vaccination could be a viable option. Smartphone-based chatbots offer promising opportunities for improving vaccine knowledge and addressing barriers encountered by ethnic minorities.
Journal of Medical Virology
22.11.2024
Journal of Medical Virology, Volume 96, Issue 11, November 2024.
BMC Infectious Diseases
13.11.2024
. Abstract. . Background. Influenza is a major cause of morbidity and mortality. Influenza A virus (IAV) is one of the most important pathogens causing influenza and often causes global pandemics due to its tendency to mutate. We aim to use epidemiology based on wastewater and respiratory specimens to understand the occurrence of influenza A virus infections in Taiyuan City. . . .
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Medscape Infectious Diseases
24.01.2025
Most commonly used drugs don’t reduce symptoms, hospitalizations, or mortality rates for low- and high-risk patients. . Medscape Medical News
Eurosurveillance latest updates
13.12.2024
… format for weeks 40/2023 to 9/2024. . . Results. Twenty-nine EU/EEA countries reported 154,718 influenza virus detections (primary care sentinel and non-sentinel combined), of which 97% (150,692) were type A and 3% (4,026) were type B. Of the subtyped influenza A viruses, 30,463 (75%) were influenza A(H1)pdm09 and 10,174 (25%) were influenza A(H3). For 809 (20%) of the type B viruses, the lineage was determined; all were B/Victoria/2/87 lineage, and none were B/Yamagata/16/88 lineage.
Eurosurveillance latest updates
13.12.2024
An outbreak of influenza A(H1N1)pdm09 viruses exhibiting cross-resistance to oseltamivir and peramivir occurred in Yokohama, Japan, in September 2024. Among 24 students in a class, 11 were diagnosed with influenza or influenza-like illness, and viruses harbouring the NA H275Y and HA Q210H substitutions were isolated from four. Deep sequencing analysis confirmed the clonal spread of these mutants. Antigenic analysis revealed differences from the vaccine strain.
Morbidity and Mortality Weekly Report (MMWR)
15.11.2024
This report describes data from two national influenza surveillance networks on antiviral treatment of hospitalized children and adolescents with influenza.
Morbidity and Mortality Weekly Report (MMWR)
7.11.2024
This report describes serologic testing to identify recent highly pathogenic avian influenza infections among dairy workers in two states.
Morbidity and Mortality Weekly Report (MMWR)
7.11.2024
This report describes dairy farmworkers in Colorado who were interviewed about PPE use during work activities around cows infected with highly pathogenic avian influenza.
Morbidity and Mortality Weekly Report (MMWR)
1.11.2024
This report describes influenza vaccination and COVID-19 vaccination coverage among health care personnel during the 2023-24 respiratory virus season (October 1, 2023-March 31, 2024).
Eurosurveillance latest updates
27.09.2024
. Background. Influenza viruses can cause large seasonal epidemics with high healthcare impact and severity as they continually change their virological properties such as genetic makeup over time. . . Aim. We aimed to monitor the characteristics of circulating influenza viruses over the 2022/23 influenza season in the EU/EEA countries.
Morbidity and Mortality Weekly Report (MMWR)
19.09.2024
This report describes levels of influenza A virus and the H5 subtype detected in wastewater in some states.
Morbidity and Mortality Weekly Report (MMWR)
29.08.2024
This report describes the first known cluster of U.S. human influenza A(H5) cases.
Eurosurveillance latest updates
2.08.2024
…eli hospitals provided serum to screen for antibodies to influenza virus using the haemagglutination inhibition assay. During the season, active monitoring for the development of ARI symptoms was conducted twice a week by RT-PCR testing of nasal swabs for influenza and respiratory syncytial virus (RSV). Workplace presenteeism and absenteeism were documented. We calculated incidences of influenza- and RSV-associated ARI and applied sampling weights to make estimates representative of the source population.
Eurosurveillance latest updates
26.07.2024
We investigated the thermostability of four European avian influenza A(H5N1) viruses in whole and semi-skimmed milk and their replication in bovine kidney and lung cells amid the current influenza A(H5N1) dairy cattle outbreak in the United States. Results showed strain-dependent differences in thermal inactivation, particularly in whole milk, and variable replication efficacy in lung cells.
Morbidity and Mortality Weekly Report (MMWR)
25.07.2024
This report describes symptom monitoring and testing among exposed dairy and poultry workers in Michigan during the H5N1 outbreak.
Eurosurveillance latest updates
22.06.2024
Highly pathogenic avian influenza (HPAI) has caused widespread mortality in both wild and domestic birds in Europe 2020–2023. In July 2023, HPAI A(H5N1) was detected on 27 fur farms in Finland. In total, infections in silver and blue foxes, American minks and raccoon dogs were confirmed by RT-PCR. The pathological findings in the animals include widespread inflammatory lesions in the lungs, brain and liver, indicating efficient systemic dissemination of the virus.
Morbidity and Mortality Weekly Report (MMWR)
25.05.2024
This report describes the joint investigation between CDC, U.S. Department of Agriculture, and the Food and Drug Administration after influenza A (H5N1) was detected in a U.S. farm worker.
Medscape Infectious Diseases
18.05.2024
The U.S. Centers for Disease Control and Prevention (CDC) on Tuesday released data on influenza A found in wastewater in a public dashboard that could assist in tracking the. . Reuters Health Information
Eurosurveillance latest updates
26.04.2024
A severe outbreak of influenza A(H1N1pdm09) infection in seven children (median age: 52 months) occurred between December 2023 and January 2024 in Tuscany, Italy. Clinical presentation ranged from milder encephalopathy to acute necrotizing encephalopathy (ANE) with coma and multiorgan failure; one child died.
Eurosurveillance latest updates
12.04.2024
…ropean Mortality Monitoring Network (EuroMOMO) has observed excess mortality in Europe. During weeks 48 2023–6 2024, preliminary results show a substantially increased rate of 95.3 (95% CI: 91.7–98.9) excess all-cause deaths per 100,000 person-years for all ages. This excess mortality is seen in adults aged 45 years and older, and coincides with widespread presence of COVID-19, influenza and respiratory syncytial virus (RSV) observed in many European countries during the 2023/24 winter season. .
Eurosurveillance latest updates
23.02.2024
Influenza A viruses circulated in Europe from September 2023 to January 2024, with influenza A(H1N1)pdm09 predominance. We provide interim 2023/24 influenza vaccine effectiveness (IVE) estimates from two European studies, covering 10 countries across primary care (EU-PC) and hospital (EU-H) settings. Interim IVE was higher against A(H1N1)pdm09 than A(H3N2): EU-PC influenza A(H1N1)pdm09 IVE was 53% (95% CI: 41 to 63) and 30% (95% CI: −3 to 54) against influenza A(H3N2).
Eurosurveillance latest updates
16.02.2024
The Canadian Sentinel Practitioner Surveillance Network reports mid-season 2023/24 influenza vaccine effectiveness (VE) of 63% (95% CI: 51–72) against influenza A(H1N1)pdm09, lower for clade 5a.2a.1 (56%; 95% CI: 33–71) than clade 5a.2a (67%; 95% CI: 48–80), and lowest against influenza A(H3N2) (40%; 95% CI: 5–61).