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Søgning på udtrykket 'sofa' giver 24 resultater
Dokumenter [2] Sider [1] Nyt fra tidsskrifterne [+20] Aktuelle smitsomme sygdomme [1]
Dokumenter [2]
Disse rekommandationer retter sig mod voksne indlagt med mistænkt sepsis og septisk shock. Se flowchart på infmed.dk/bilag#sepsis_flowchart_(2021).pdf
Bilag med flowchart til vurdering og behandling af sepsis og septisk shock, se også infmed.dk/guidelines#sepsis_guidelines_(2021).pdf
Sider [1]
Nedenstående Sequential Organ Failure Assessment (SOFA) score udregnes på baggrund af den let modificerede SOFA-score, som fremgår af Dansk Selskab for Infektionsmedicins vejledninger vedrørende sepsis.
Nyt fra tidsskrifterne [+20]
Der er mere end 20 resultater, måske du vil se flere resultater her?
PLoS One Infectious Diseases
17. september 2025
[…] Lu, Zhouzhou Dong, Longqiang Ye, Yi Gao, Zaixing Zheng Background Sepsis is a leading cause of death, necessitating early prediction of mortality risk. Objective To systematically review the predictive efficacy of the Sequential Organ Failure Assessment (SOFA), procalcitonin (PCT), lactate, quick Sequential Organ Failure Assessment (qSOFA), and lactate-adjusted qSOFA (LqSOFA) for the risk of death in patients with sepsis. Methods According to PRISMA-DTA guidelines, PubMed, Embase, the Cochrane Library, […]
BMC Infectious Diseases
1. maj 2025
[…] to the ICUs of Ghaem and Imam Reza tertiary hospitals in Mashhad with a definitive diagnosis of COVID-19 from March 21, 2020, to December 1, 2021, were evaluated for disease severity assessment criteria, including SOFA, SAPS III, and MPM II. Results One hundred seventy-two patients with COVID-19 who were admitted to the ICU were evaluated (147 patients in the non-survivor group and 25 patients in the survivor group. The median SAPS, SOFA, and MPM scores were significantly higher in non-survivors […]
PLoS One Infectious Diseases
24. januar 2025
[…] through forward stepwise logistic regression, and a nomogram was created based on these factors. The discriminative ability of the nomogram was assessed using the area under the receiver operating characteristic curve (AUC) and compared with the SOFA score. The model’s consistency was evaluated using the C-index, and the improvement in performance over the SOFA score was calculated using integrated discrimination improvement (IDI) and net reclassification improvement (NRI). Results Five […]
Malaria Journal
24. november 2024
[…] the association between damage to infrastructure (health care facilities and schools) following Cyclone Idai and malaria outcomes: malaria incidence, severe malaria, and administration of intermittent preventative treatment in pregnancy (IPTp) in Sofala Province, Mozambique. Methods To quantify infrastructure damage, historical satellite imagery was assessed visually using Google Earth Pro®. Damage to 66 school and 105 health centres was assessed for severity and duration. Location data was […]
BMJ Open
24. april 2025
[…] assess the degree to which we can replicate a study between a regional and a national database of electronic health record data in the UK. The original study examined the risk factors associated with hospitalisation following COVID-19 infection in people with diabetes. DesignA replication of a retrospective cohort study. SettingObservational electronic health record data from primary and secondary care sources in the UK. The original study used data from a large, urbanised region (Greater […]
BMC Infectious Diseases
31. oktober 2025
[…] 26, 2012, to October 1, 2023. The primary outcomes were 28-day mortality and in-hospital mortality, and the secondary outcomes were intensive care units (ICU) length of stay, duration of mechanical ventilation, length of vasopressor use, changes in SOFA score, and PaO2/FiO2 ratio. Random-effects models were employed to analyze the study outcomes. The Cochrane Systematic Review Guidelines and the GRADE system were utilized evaluated the risk of bias and the quality of evidence. Results A total of […]
BMC Infectious Diseases
27. oktober 2025
[…] culture-confirmed bacteremic IED and 67 (50.0%) were antimicrobial resistant. Median age was 79 years. Fourteen (10.4%) patients died during index hospitalization and 41 (35.7%) were readmitted within 12 months. Almost 80% of patients showed a SOFA score increase of ≥2 points, and 9.0% suffered from septic shock. Bacteremic patients had higher readmission rates (35.8% versus 28.0%), and longer hospital stays (mean 13.1 days). Patients with AMR infections were admitted with significantly worse SOFA scores […]
BMC Infectious Diseases
25. oktober 2025
[…] treatment). Inflammatory parameters (C-reactive protein (CRP), lactate dehydrogenase (LDH), and serum ferritin (SF) and lactate), patient conditions, and Sequential Organ Failure Assessment (SOFA) scores were monitored and recorded on the fifth and seventh days of hospitalization, and the day of discharge from the intensive care unit (ICU). Results While mortality had no difference between the groups (p > 0.05), the duration of receiving inotrope was significantly shorter in the intervention group (p […]
BMC Infectious Diseases
22. oktober 2025
[…] IVAC 1.3 and PVAP 4.7. Additionally 158 VAP episodes (14.8%, 7.09/1000 MV days) were observed, 85 (45.9%, 4.99/1000 MV days) of them fit the definition of a concurrent VAE criteria. Risk factors for VAE included a Sequential Organ Failure Assessment (SOFA) score greater than 7 on admission (odds ratio [OR]: 1.75; 95% confidence interval [CI]: 1.23–2.47), the presence of a tracheostomy (OR:1.78; CI:1.19-2.65), and antibiotic use within the previous 90 days (OR:2.41; CI:1.09-4.20) were risk factors for […]
Neutropenic sepsis and septic shock in ICU patients: A single-center experience over the last decade
PLoS One Infectious Diseases
15. oktober 2025
[…] infections were pulmonary (24.8%) and hepatobiliary or gastrointestinal (23.8%). Gram-negative bacilli predominated. Predictors of in-hospital mortality were older age (odds ratio [OR], 1.04; 1.01–1.07; P = 0.005) and worse SOFA score (OR, 1.22; 1.05–1.42; P = 0.009). Aminoglycoside therapy predicted lower in-hospital mortality regardless of infection site and renal function (OR, 0.30; 0.14–0.63; P = 0.002). Early source-control interventions were not significantly associated with […]
BMC Infectious Diseases
27. september 2025
[…] Methods A total of 257 septic patients (Sepsis-3 criteria) were included. Patients were divided into two groups based on SI-AKI development (with SI-AKI, n = 133; without SI-AKI, n = 124). All patients had complete blood count with leukocyte formula, CRP, PCT, SOFA and qSOFA score available. Statistical analysis included non-parametric Mann-Whitney test, Spearman’s correlations, ROC curve analysis, as well as binary logistic regression in order to identify independent predictors of SI-AKI. Results CRP (p […]
PLoS One Infectious Diseases
25. september 2025
[…] Propensity score matching (1:1) without replacement was used to create comparable groups for Cox regression analysis of 30-day all-cause mortality. Results Among 211 CII patients (mean age (SD) 61 (16) years, 57% male), 85 (40.3%) had BSIs. The median SOFA and APACHE II scores were 7 (IQR 4–11) and 16 (IQR 14–20), respectively. Immunosuppression was due to hematologic malignancy (37.4%), solid tumors (27.0%), autoimmune diseases (19.0%), solid organ transplantation (5.7%), and other causes (10.4%). […]
Critical Care Explorations
31. august 2025
[…] phenotypes. DESIGN, SETTING, AND PARTICIPANTS: Prospective observational study in four ICUs enrolling critically ill patients with septic shock. MAIN OUTCOMES AND MEASURES: Endotoxin activity assay (EAA) results, Sequential Organ Failure Assessment (SOFA), and multiple organ dysfunction (MODS) and 28-day mortality. RESULTS: We enrolled 90 patients aged 25–95 years and set an EAA cutoff of greater than or equal to 0.6 together with SOFA greater than 11 or MODS greater than 9 to define endotoxic septic […]
PLoS One Infectious Diseases
30. august 2025
[…] Any norepinephrine use, Blood.transfusion, Chlorine disinfectant, Tracheotomy on the occurrence of HARTI in ICU patients. And use R studio to construct nomogram model. Result The results indicate that MONO (7.16[2.16,23.71]), BUN (0.24[0.06,0.88]), SOFA (4.5[1.48,13.74]), chlorine disinfectant (500 mg/L) (0.02[0,0.07]) in the choice of disinfection method, and bed railing (0.14[0.04,0.48]), micro-infusion pump (0.31[0.1,0.98]) in the area of disinfection are independent predictors of HARTI occurrence. […]
BMJ Open
2. august 2025
[…] adult patients requiring mechanical ventilation and vasopressor support. Participants will receive either intermittent or continuous enteral nutrition for 7 days, with the primary endpoint being the change in the Sequential Organ Failure Assessment (SOFA) score from Day 1 to Day 7 or ICU discharge. Secondary endpoints include nutritional intake, metabolic markers, gastrointestinal tolerance, ICU-acquired infections and mortality rates. Quality of life will be assessed at discharge. A total of 174 […]
Infection
23. juli 2025
[…] (2.08; 1.24–3.50), liver disease (1.81; 0.99–3.28), healthcare-associated acquisition (2.29; 1.52–3.44), Pitt index > 3 (3.59; 2.30–5.61), SOFA ≥ 2 (1.66; 1.04–2.64), and urinary tract source (0.37; 0.24–0.56). The predictive score showed an AUROC of 0.78 (95% CI 0.74–0.83) in the DC and 0.78 (95% CI 0.73–0.84) in the VC. Conclusion We developed and internally validated a predictive scoring model to identify patients with E. coli bacteraemia at high and low risk of crude mortality on day 30 of […]
PLoS One Infectious Diseases
22. juli 2025
[…] logistic regression analysis. Results The 28-day ICU mortality rates were 9.08% and 9.49% in the training and validation cohorts, respectively. The final nomogram incorporated 11 independent predictors: red cell distribution width (RDW), SOFA score, lactate, pH, 24-hour urine output, platelet count, total protein, temperature, heart rate, GCS score, and white blood cell (WBC) count. The model showed good discrimination in both the training (AUC: 0.805) and validation (AUC: 0.756) cohorts. The […]
Critical Care Medicine
4. juni 2025
[…] countries. PATIENTS: Adult patients with sepsis or septic shock. INTERVENTIONS: Mega-dose (1024 mg) esomeprazole or placebo over a 72-hour period. MEASUREMENTS AND MAIN RESULTS: The primary outcome was mean daily Sequential Organ Failure Assessment (SOFA) score to day 10. Secondary outcomes included antibiotics-free days, ICU-free days at day 28, and all-cause mortality. We also conducted a mechanistic study of the in vitro effects of esomeprazole in sepsis. We randomized 307 patients and assigned 148 […]
Critical Care Explorations
26. maj 2025
[…] mechanical ventilation, or oxygen therapy with Pao2/Fio2 less than 200. MAIN OUTCOMES AND MEASURES: The primary outcome was death in the intensive care unit. We fit logistic regression models using a modified Sequential Organ Failure Assessment (SOFA) score with and without age in the derivation cohort and assessed predictive performance in the validation cohort using area under the receiver operating characteristic curves (AUCs) and compared observed and predicted mortality. RESULTS: The final […]
BMJ Open
24. maj 2025
[…] particularly among men aged 25–34 years. DesignA mixed-methods, cross-sectional study using quantitative and qualitative approaches. SettingIn Mozambique, over two million individuals live with HIV. This study was conducted in Maputo, Nampula and Sofala provinces. ParticipantsThe study comprised 10 focus group discussions with MLHIV aged 18–35 years and 58 indepth interviews with MLHIV aged 15–35 years across diverse subpopulations. A quantitative cross-sectional survey was completed by 1934 MLHIV […]
Aktuelle smitsomme sygdomme [1]
Aktuelle smitsomme sygdomme [1]
ProMED
6. februar 2025
[…] there have been no new cases notified in theprevious 24 hours, and for the past 14 days there have been no measlesdeaths. The measles cases were reported in Cabo Delgado, Niassa, and Nampulain the north, and in the central provinces of Zambezia and Sofala. [Of the 1191 cases,] 428 cases were diagnosed in Niassa, 351 inNampula, 341 in Cabo Delgado, 42 in Sofala, and 29 in Zambezia. Of the31 known measles deaths, 17 were in Cabo Delgado, 11 in Nampula, and 3in Niassa. Couto stressed the need for […]