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Version 1, oktober 2024.
Denne guideline omfatter konkret håndtering af mistænkte og bekræftede tilfælde af mpox med det formål at diagnosticere mpox, behandle tilfældet samt forebygge smittespredning samt forholdsregler ifm. vaccination mod infektionen.
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Journal of the American Medical Association
18.12.2024
The modified vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine is approved in several countries for use in the prevention of mpox and smallpox in adults. New research suggests it’s also safe and produces an immune response in adolescents, a population affected by the current clade I mpox outbreak.
Infection
4.12.2024
Abstract. . Background. The JYNNEOS vaccine (two doses given 28 days apart) was recommended in the United States for people at high risk of exposure to monkeypox virus during the 2022 mpox outbreak. Our objective was to assess the safety of JYNNEOS using two complementary epidemiologic methods. . . . Methods. This observational cohort included patients of eight
Journal of the American Medical Association
3.12.2024
On October 3, the World Health Organization (WHO) authorized the first mpox in vitro diagnostic test under its Emergency Use listing procedure. As mpox cases continue to spread regionally in Africa, this measure will help improve both timely treatment and containment of the virus, the WHO stated.
Tropical Medicine & International Health
2.12.2024
Tropical Medicine &International Health, EarlyView.
Science
28.11.2024
Science, Volume 386, Issue 6725, Page 954-954, November 2024.
Journal of the American Medical Association
20.11.2024
This study assesses mpox-specific immune responses for 12 months after MVA-BN vaccination.
PLoS One Infectious Diseases
13.11.2024
by John Gilmore, David Comer, David J. Field, Randal Parlour, Adam Shanley, Chris Noone . Background In May 2022, a global surge in mpox cases, typically endemic to Western and Central Africa, particularly affected gay, bisexual, and other men who have sex with men (gbMSM). This study examines gbMSM communities’ experiences and perceptions around Ireland’s public health response to the outbreak. Methods A cross-sectional mixed-methods online survey was conducted. Qualitative data were analysed using r
Journal of the American Medical Association
12.11.2024
The US Centers for Disease Control and Prevention (CDC) issued an updated advisory outlining prevention strategies for people visiting countries with widespread clade I mpox virus outbreaks. These strategies include getting the modified vaccinia Ankara–Bavarian Nordic (JYNNEOS) vaccine, which the World Health Organization recently prequalified.
Journal of the American Medical Association
6.11.2024
A single dose of the modified vaccinia Ankara–Bavarian Nordic (MVA-BN) smallpox vaccine is 58% effective against mpox infection, according to a study in The BMJ. The results were based on 9800 men aged 18 years or older in Canada and come as mpox cases continue to spread in regions of Africa.
Current Opinion in Infectious Diseases
1.11.2024
Purpose of review . The aim of this study was to summarize the current knowledge of therapeutic options for mpox (formerly known as monkeypox) in the context of recent outbreaks and the ongoing evolution of the virus. Recent findings . Multiple therapeutic agents, including tecovirimat, cidofovir, brincidofovir, and vaccinia immune globulin, have been used during the multicountry outbreak of mpox caused by Clade 2b monkeypox virus that began in 2022. Tecovirimat has been most extensively used, based on ef
Proceedings of the National Academy of Sciences
23.10.2024
Proceedings of the National Academy of Sciences, Volume 121, Issue 43, October 2024.
BMC Infectious Diseases
22.10.2024
. Abstract. During the 2022 mpox outbreak, our study conducted 30 interviews with a recruited sample of Chicago gay men (age 18+) during June-September to investigate their experiences of mpox, HIV/AIDS, and COVID-19. Participants were interviewed with a semi-structured guide about gay sexual identity and social experiences; HIV/AIDS, ART, and PrEP; and COVID-19 behaviors and vaccination. All 30 interview respondents had been fully vaccinated for COVID-19 and expresse
Journal of Infectious Diseases
19.10.2024
Journal of Infectious Diseases
18.10.2024
Lancet
18.10.2024
When we spoke, Jean Nachega, Co-Founder and Steering Committee Chair of the African Mpox Research Consortium (MpoxReC), had been working late on an mpox emergency discretionary grant application. Nachega, Associate Professor of Epidemiology, Infectious Diseases and Microbiology at the University of Pittsburgh School of Public Health, PA, USA, is an accomplished researcher in HIV/AIDS, tuberculosis, and COVID-19 whose focus now is the mpox emergency in his home country DR Congo and other African countries.
Journal of the American Medical Association
15.10.2024
As the mpox virus continues to spread in Africa, the World Health Organization (WHO) has launched a global emergency response plan to limit transmission. As of June 2024, the agency reported, the outbreak has resulted in nearly 100 000 confirmed cases and 200 deaths, mostly in the Democratic Republic of Congo, but also in such neighboring countries as Burundi and Kenya. Both Sweden and Thailand have reported a single travel-related case each.
Clinical Microbiology and Infection
15.10.2024
On August 14, 2024, WHO's Director-General, Dr. Tedros Adhanom Ghebreyesus, declared Mpox a Public Health Emergency of International Concern (PHEIC). This declaration followed a surge in Mpox cases, particularly those caused by clade Ib of the virus, in the Democratic Republic of the Congo and neighbouring African countries [1]. While the global spotlight has primarily focused on adult populations, especially men who have sex with men (MSM), The paediatric risk from Mpox remains significantly underrecognise
Emerg Microbes Infect
12.10.2024
Volume 13, Issue 1, December 2024 .
Clinical Infectious Diseases
8.10.2024
Abstract . Introduction . Since its global reemergence in 2022, monkeypox (mpox) has demonstrated increased incidence and severity among people with human immunodeficiency virus (HIV [PWH]). Predictors of mpox diagnosis, vaccination, and outcomes among PWH are limited.Methods . We included PWH with primary care visits after 1 January 2022 at 9 US sites participating in the Centers for AIDS Research Network of Integrated Clinic Systems Network. We identified mpox diagnosed between 1 June 2022 and 31 May 2023
Clinical Microbiology and Infection
6.10.2024
The current epidemiological situation regarding mpox, a zoonotic viral disease caused by the monkeypox virus (MPXV), is complex. Multiple simultaneous epidemics involving distinct clades of MPXV are occurring across different geographic regions, each affecting distinct at-risk populations. Particularly concerning is the emergence of clade Ib, about which much remains unknown.
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Eurosurveillance latest updates
29.11.2024
In October 2024, the first imported mpox clade Ib case was confirmed in Germany in an individual in their thirties returning from Rwanda. In this report we summarise the response from the public health service in North Rhine-Westphalia related to case management, contact tracing and institutional collaborations. Our findings highlight the importance of a coordinated public health response in the management of imported mpox cases and in preventing the transmission of mpox clade Ib in Germany and beyo
Eurosurveillance latest updates
29.11.2024
An unprecedented upsurge in mpox, caused by clade I of the monkeypox virus (MPXV) was noted in Central Africa in 2024. The first mpox case with MPXV clade Ib outside Africa was reported in Sweden in mid-August. The case experienced a mild disease course after travelling to an affected country. No additional cases of this clade have been detected in Sweden. Strengthened public health measures and surveillance including whole genome sequencing are crucial to prevent establishment of novel MPXV clades. .
Medscape Infectious Diseases
13.11.2024
Prompt identification of suspected mpox cases is a vital first step to maintaining workforce safety, experts said at a WHO webinar. . Medscape Infectious Diseases
Medscape Infectious Diseases
11.11.2024
The World Health Organization will convene a meeting of its Emergency Committee next week to determine whether mpox remains a global health crisis, it said in a statement on. . Reuters Health Information
Medscape Infectious Diseases
2.11.2024
Britain has detected its first case of new mpox variant clade Ib, the country's health security agency (UKHSA) said on Wednesday, adding that the risk to the population. . Reuters Health Information
Eurosurveillance latest updates
18.10.2024
In response to the increasing number of mpox cases caused by monkeypox virus (MPXV) clade I in the African continent and the first reported travel-related clade Ib case of mpox in EU/EEA, the European Centre for Disease Prevention and Control surveyed national capability for detection and characterisation of MPXV in the EU/EEA. The results showed high level of capability for case confirmation by PCR, alongside molecular typing methods for identification of MPXV clades and/or clade I subclades within the EU/
Eurosurveillance latest updates
18.10.2024
We analysed mpox cases in Burundi from July to September 2024, following the introduction of Clade Ib virus. Of 607 samples from the whole population of suspected cases, 154 were PCR-positive, of whom 85 were children under 15 years, with a higher proportion of female children testing positive. Geographical analysis demonstrates case concentration in Bujumbura Mairie (91/154). Age- and sex-specific interventions, as well as community engagement, are important for outbreak containment, as are targeted public
Medscape Infectious Diseases
14.10.2024
The World Health Organization said on Monday it had approved Bavarian Nordic's mpox vaccine for adolescents aged 12 to 17 years, an age group considered especially. . Reuters Health Information
Medscape Infectious Diseases
11.10.2024
U.S. health officials have identified a cluster of cases caused by an mpox variant that are resistant to Siga Technologies' antiviral tecovirimat, branded as TPOXX, in five. . Reuters Health Information
Morbidity and Mortality Weekly Report (MMWR)
11.10.2024
This report describes a cluster of mpox cases cause by tecovirimat-resistant mpox.
Morbidity and Mortality Weekly Report (MMWR)
11.10.2024
This report describes mpox risk among men who have sex with men and transgender persons who reported close contact with a person with mpox.
Medscape Infectious Diseases
5.10.2024
The World Health Organization authorized Abbott Laboratories' mpox diagnostic test for emergency use on Thursday, the first such approval in the agency's effort to bolster. . Reuters Health Information
Medscape Infectious Diseases
24.09.2024
U.S. President Joe Biden will announce on Tuesday the donation of 1 million mpox vaccine doses and at least $500 million to African countries to support their response to. . Reuters Health Information
Medscape Infectious Diseases
20.09.2024
With more than 200 mpox-related deaths reported globally, the EMA has approved Imvanex for adolescents aged 12-17 years. . Medscape Medical News
Medscape Infectious Diseases
18.09.2024
In an emulated target trial, a single dose of modified vaccinia Ankara-Bavarian Nordic vaccine was moderately effective in preventing mpox infection. . Medscape Medical News
Medscape Infectious Diseases
17.09.2024
The UK government has ordered more than 150,000 doses of Bavarian Nordic's mpox vaccine to boost its preparedness against a new form of the virus currently spreading in. . Reuters Health Information
ECDC Epidemiological Update
17.09.2024
In 2024, over 24 000 confirmed or suspected mpox cases due to MPXV clade I and clade II, including over 600 deaths, have been reported from Africa Union Member States, including over 5 000 confirmed cases.
Medscape Infectious Diseases
14.09.2024
The World Health Organization and partners on Friday set up a scheme to help bring mpox vaccines, tests and treatments to the most vulnerable people in the world’s poorest. . Reuters Health Information
Medscape Infectious Diseases
13.09.2024
Canada is donating 'up to 200,000' doses of mpox vaccine, a government spokesperson said on Wednesday. . Reuters Health Information
ECDC Epidemiological Update
10.09.2024
Since the beginning of mpox monitoring in 2022, and as of 31 July 2024, over 100 000 confirmed cases of mpox due to monkeypox virus (MPXV) clade I and clade II, including over 200 deaths among confirmed cases, have been reported by more than 120 countries globally.