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Dokumenter [3]
Fællesregional retningslinje for udlevering af forebyggende medicin mod HIV (PrEP), udgivet af Danske Regioner.
Henvendelse til Danske regioner
Arrangereret af AIDS-fondet og CHIP
Sider [3]
Her kan du læse om arbejdsgrupperne og diverse udvalg under Dansk Selskab for Infektionsmedicin. Arbejdsgrupper: Arbejdsgrupper under Dansk Selskab for Infektionsmedicin organiseres med en kerne på typisk 4-8 personer (maks. 10) herunder en tovholder. Bestyrelsen kan oprette og lukke arbejdsgrupper. Ved oprettelse af arbejdsgruppe sender bestyrelsen invitation til infektionsmedicinske centre i alle regioner. Alle DSI medlemmer, med undtagelse af firma-medlemmer, kan indgå i arbejdsgrupper. Har m…
…e HIV-Infected Host: Epidemiology and Pathogenesis in the Antiretroviral Era Curr HIV/AIDS Rep. 2015; 12: 6?15. HIV - persistence on ART & cure research:. Margolis et al: Latency reversal and viral clearance to cure HIV-1. Science. 2016; 253: aaf6517. PREP og PEP:. Fonner et al. Effectiveness and safety of oral HIV preexposure prophylaxis for all populations: AIDS 2016 Jul 31;30(12):1973-83. Rodger et al. Sexual Activity Without Condoms and Risk of HIV Transmission in Serodifferent Couples When the HIV-…
…dling (Lene). 12:00-12:45 Resistens (Ann-Brit Eg Hansen). 12:45-13:30 Frokost. 13:30-14:15 Klinisk håndtering af HIV I (Ole og Lene). 14:15-14.30 Pause. 14:30-15:30 Klinisk håndtering af HIV 2 - cases (Alle). 15:30-15:45 Pause. 15:45-16:30 PrEP, Long acting antiretrovirals og STDs (Gitte Kronborg). . Torsdag den 13. oktober. 08:15-09:15 HIV og Komorbiditet/EACS Guidelines (Lene). 09:15-09:30 Pause. 09:30-10:15 Cocomo, danske data vedr HIV og co-morbiditet (Susanne Dam). 10:15-1…
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Journal of the American Medical Association
14.01.2025
The rates of health care–associated infections (HAIs) at US hospitals fell in 2023, which reflects a continuing downward trend following significant increases amid the COVID-19 pandemic.
Journal of Acquired Immune Deficiency Syndromes
11.01.2025
Introduction: . There are persistent race- and ethnicity-based disparities in HIV incidence among gay and bisexual men who have sex with men (GBMSM) in the United States, partially driven by inequities in distribution of pre-exposure prophylaxis (PrEP). We assessed how additional modalities of PrEP beyond daily oral might affect uptake of PrEP and ongoing disparities in HIV incidence in the US. Methods: . In an online survey of GBMSM in the US, we presented participants with descriptions of each PrEP moda…
Journal of Acquired Immune Deficiency Syndromes
4.01.2025
Background: . Pre-exposure prophylaxis for HIV prevention (PrEP) prescriptions in the U.S. have increased, yet only 15% of individuals assigned female at birth who could benefit from PrEP had received prescriptions as of 2022, with marked racial disparities. Setting: . Georgia has the highest HIV incidence of any U.S. state, with over half of new cases occurring in Atlanta. Accounting for approximately 1-in-5 cases, cisgender women living in Atlanta may benefit from clinic-based efforts to increase PrEP u…
AIDS
29.12.2024
Objective: . We developed Healthy Families-PrEP to support perinatal women to use HIV prevention strategies. Design: . Single arm study to evaluate PrEP use among pregnant women exposed to the intervention. Methods: . We offered safer conception counselling including TDF/FTC as PrEP with adherence support (Healthy Families-PrEP) for women planning for pregnancy in South Africa with a partner with HIV or unknown serostatus. Women completed pregnancy and HIV testing quarterly and were followed for one year…
Journal of Acquired Immune Deficiency Syndromes
28.12.2024
Background: . Pregnant women are vulnerable to HIV acquisition. Oral HIV pre-exposure prophylaxis (PrEP) is safe and effective for use during pregnancy. We describe PrEP adherence among pregnant women using multiple measures. Methods: . We conducted a secondary data analysis among women enrolled in a study evaluating an adherence intervention for PrEP among those planning for and with pregnancy in South Africa. Our analysis included women who used PrEP and became pregnant. Longitudinal PrEP use was assess…
BMJ Open
16.12.2024
… health resource management, where scarcity impairs pandemic response resulting in increased disease transmission, delayed patient care and poorer health outcomes. In the EU PANDEM-2 project, we aimed to identify essential resource parameters for pandemic preparedness and response in the context of an emerging viral respiratory illness. . Design. After performing a systematic literature review, we conducted a Delphi study consisting of a structured questionnaire and consensus round with two separate panels…
Clinical Microbiology and Infection
9.12.2024
The emergence of Post-COVID-19 Condition (PCC) following SARS-CoV-2 infection underscores the critical need for preparedness in addressing future Post-Acute Infection Syndromes (PAIS), particularly those linked to epidemic outbreaks. The lack of standardized clinical and epidemiological data during the COVID-19 pandemic has significantly hindered timely diagnosis and effective treatment of PCC, highlighting the necessity of pre-emptively standardizing data collection in clinical studies to better define and…
PLoS One Infectious Diseases
7.12.2024
by ChenXin Zhang, Jia Li, HaiJin Suo, JianPing Bai . Purpose The impact of non-fixation of mesh in transabdominal preperitoneal (TAPP) inguinal hernia repair has not been fully assessed. The aim of this meta-analysis was to comprehensively compare the clinical outcomes of non-fixation and fixation of mesh in TAPP to determine whether non-fixation could affect the outcomes. Methods PubMed, Embase and CENTRAL were searched for studies on TAPP repair of inguinal hernia and mesh fixation published up to June …
Journal of Acquired Immune Deficiency Syndromes
5.12.2024
Background: . Despite high oral pre-exposure prophylaxis (PrEP) uptake among young heterosexual cisgender women, early discontinuation is frequent. It is unclear whether this aligns with potential HIV exposure. Methods: . Young women 16-25 years and ≥1 of their male partners were enrolled in separate but linked longitudinal HIV PrEP studies in Kampala, Uganda from 2018-2021. Data on sexual behavior, PrEP use, STI positivity, and Y chromosome DNA (Yc DNA; a marker for condomless sex) were collected at en…
Journal of Acquired Immune Deficiency Syndromes
5.12.2024
Background. . The best therapeutic management for people with HIV who have a history of pre-exposure prophylaxis (PrEP) is still debated. Objectives. . The aim of this study was to describe recent HIV infections in PrEP users compared with people never exposed to PrEP. Methods. . Multicentre retrospective analysis evaluating all recent HIV infections from 2018 to 2021 within the Italian Cohort Naive Antiretrovirals (ICONA). PWH, PrEP-experienced or not, were compared using chi-squared test and Wilcoxon r…
Journal of Medical Virology
1.12.2024
Journal of Medical Virology, Volume 96, Issue 12, December 2024.
Journal of Acquired Immune Deficiency Syndromes
20.11.2024
Introduction: . Adolescent girls and young women (AGYW) in Kenya have low pre-exposure prophylaxis (PrEP) initiation rates in part due to stigmatizing interactions with health care providers. Our recent randomized clinical trial of a standardized patient actor (SP) training intervention for providers found higher quality PrEP delivery at intervention sites, however it was unclear whether improved service quality improved PrEP initiation. Methods: . This analysis used routine records from facilities partic…
PLoS One Infectious Diseases
19.11.2024
…Boyd, Seraiya Wright, Joseph D. Tucker, Manya Magnus . HIV incidence among young people (Black and Latinx women and men who have sex with men ages 16–24 years), in the United States is high. Traditional top-down approaches for pre-exposure prophylaxis (PrEP) social marketing are not effectively reaching this population. Crowdsourcing is a promising approach to engaging young people in the development of innovative solutions to raise awareness and use of PrEP among those at highest risk of HIV. This study…
PLoS One Infectious Diseases
13.11.2024
by Julien Brisson, Mariangela Castro-Arteaga, Dorothy Apedaile, Amaya Perez-Brumer . Introduction Pre-exposure prophylaxis (PrEP) stands as an effective tool in preventing HIV transmission among individuals at risk of HIV infection. However, the effectiveness of daily oral PrEP is contingent on the adherence of its users, which can pose a challenge for many individuals. Various studies have explored different interventions aimed at bolstering PrEP adherence. One recurring type of intervention revolves arou…
Journal of the American Medical Association
12.11.2024
This JAMA Insights discusses the expanding PrEP options for preventing HIV, including the considerations for initiation and follow-up and implementation challenges of these medications.
Journal of the American Medical Association
12.11.2024
To the Editor In the research and operations niche of hospital capacity strain and preparedness, although surges have historically been defined according to an unexpected large number of patients (eg, a mass casualty event), many have argued for a more nuanced definition that also includes any number of patients with high acuity (or higher acuity than the norm for the treating location) or with unique care needs (such as enhanced personal protective equipment or specialized personnel), or any isolated or si…
Journal of the American Medical Association
12.11.2024
In Reply We appreciate Dr Anesi’s interest in our Research Letter, which reported that ransomware attacks disrupting care delivery in targeted hospitals in California from 2014 to 2020 led to an increase in emergency department visits at nearby facilities.
BMC Infectious Diseases
7.11.2024
… Abstract. . Objectives. Disruptive public health risks and events, including infectious disease outbreaks, are inevitable, but their effects can be mitigated by investing in prevention and preparedness. We assessed the epidemic preparedness and response capacities of health systems in 186 countries from 2018 to 2022. . . . Methods. We utilized data from the …
Clinical Infectious Diseases
1.11.2024
Abstract . In a low-barrier long-acting PrEP program in a safety-net setting, permitting same-day or next-day initiation, 85% of injections were on-time, and six-month retention was 83%, surpassing outcomes from most previously-reported oral PrEP studies. With drop-in, wrap-around services, similar retention among housing-insecure populations was seen. Long-acting PrEP expansion is urgently needed.
Aktuelle smitsomme sygdomme [+20]
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Medscape Infectious Diseases
21.10.2024
Large study showed current statistical trends of PrEP access vs PrEP need. . Medscape Medical News
Eurosurveillance latest updates
30.08.2024
The East African Community (EAC) is experiencing an unprecedented, emerging mpox outbreak since July 2024 in five of eight partner states. We highlight rapid regional response measures, initiated August 2024 coordinated by EAC: field deployment of six mobile laboratories in Burundi, Rwanda, Uganda, Tanzania, Kenya, South Sudan to high-risk areas, donation of one mobile laboratory to Democratic Republic of the Congo and genomic monkeypox virus (MPXV) surveillance support. These interventions aim to limit loc…
Medscape Infectious Diseases
22.08.2024
Preexposure prophylaxis prescription reversals and abandonments were lower for patients seen by primary care clinicians than by other noninfectious disease clinicians. . MDedge News
Medscape Infectious Diseases
25.07.2024
Final results of the highly anticipated PURPOSE 1 trial of lenacapavir show the shots prevent new infections without many side effects. . Medscape Medical News
Medscape Infectious Diseases
5.07.2024
Patients at a high risk for HIV infection who received preexposure prophylactic injections with lenacapavir had 100% efficacy in a phase 3 clinical trial. . Medscape Medical News
Morbidity and Mortality Weekly Report (MMWR)
16.05.2024
This report describes the investigation of cases in the Democratic Republic of the Congo (DRC), CDC's support to DRC, and U.S. public health preparedness activities to date.
Eurosurveillance latest updates
29.03.2024
. Background. Pre-exposure prophylaxis (PrEP) effectively prevents HIV, but its association with sexually transmitted infections (STIs) has raised concerns about risk compensation, potentially impacting the expansion of PrEP programmes. . . Aim. We examined the relationship between PrEP and the incidence of chlamydia, gonorrhoea and syphilis. . . Methods. In this prospective cohort study, we compared STI rates before and after PrEP initiation among users in the capital region of Denmark (2019–2022),…
ECDC COVID-19 updates
20.03.2024
This guidance outlines key strategic and operational considerations to inform pandemic preparedness planning round the design and implementation of public health and social measures in community settings in the EU/EEA.
Medscape Infectious Diseases
7.03.2024
AstraZeneca plans to invest 650 million pounds ($826.80 million) in Britain to boost research, development and manufacturing of vaccines, the government announced on. . Reuters Health Information
Eurosurveillance latest updates
11.10.2024
We report a considerable increase in enterovirus D68 (EV-D68) cases since July 2024, culminating in an ongoing outbreak of acute respiratory infections in northern Italy, accounting for nearly 90% of all enterovirus infections. The outbreak was identified by community- and hospital-based surveillance systems, detecting EV-D68 in individuals with mild-to-severe respiratory infections. These strains belonged to B3 and a divergent A2 lineage. An increase in adult cases was observed. Enhanced surveillance and m…
ProMED
13.01.2025
…enial. A follow-up. investigation proved that food items were stored at an 'appropriate. temperature and manner,' according to the CHP news release. However,. attention was brought to a beetroot salad, offered on both flights, as. it requires heavy manual preparation and does not require to be. reheated before serving. The menu item was suspended as a precaution. The CHP has collected samples from Cathay Pacific's in-flight food. offerings for further investigation. . Cathay Pacific emphasized their cautio…
ProMED
11.01.2025
…stration or dehorning, . - Branding, . - Shearing, and . - Sore mouth in sheep. . 'In addition, screwworms can infest the navels of newborn mammals and. mucous membranes of bodily orifices, including nostrils and sinuses,. eyes, mouth, ears, vulva, anus, prepuce, and urethral fossa. . 'It may be difficult to visualize the screwworm maggots at the wound. surface, since only the breathing tubes of the maggot are exposed. As. the larvae feed on live tissue, they burrow into the tissue, creating. a deeper and…
ProMED
11.01.2025
…uching animals, plucking poultry. feathers, or other objects that may be sources of contamination. Cook. food thoroughly before eating, especially meat, poultry, and eggs. Do. not eat raw chicken or duck eggs. Keep raw and cooked food separate. Clean food preparation equipment properly. . . Therefore, the public is requested to be aware and take care of their. health in accordance with the above prevention methods. The Ministry. of Health will continue to provide information on public health issues. on th…
Medscape Infectious Diseases
3.12.2024
Britain's Health Security Agency (UKHSA) said on Tuesday that it has secured a contract for over five million doses of the human H5 influenza vaccine as part of preparations. . Reuters Health Information
Morbidity and Mortality Weekly Report (MMWR)
28.11.2024
This report describes PrEP initiations in 37 countries as part of the United Nations Programme on HIV/AIDS.
Medscape Infectious Diseases
19.11.2024
Approximately 80% of patients who started STI-PEP via telehealth remained in HIV PrEP care after 3 months . Medscape Medical News
Eurosurveillance latest updates
26.10.2024
…ears had not reverted to pre-pandemic behaviours, possibly because they more often work from home. Although the number of contacts is lower compared to the pre-pandemic period, the effect on transmission potential of a newly emerging respiratory pathogen is limited if all age groups were equally susceptible. . . Conclusion. Continuous monitoring of contacts can signal changes in contact patterns and can define a ‘new normal’ baseline. Both aspects are needed to prepare for a future pandemic. . . .
Eurosurveillance latest updates
18.10.2024
. Background. Sweden reached the UNAIDS 90–90–90 target in 2015. It is important to reassess the HIV epidemiological situation due to ever-changing migration patterns, the roll-out of PrEP and the impact of the COVID-19 pandemic. . . Aim. We aimed to assess the progress towards the UNAIDS 95–95–95 targets in Sweden by estimating the proportion of undiagnosed people with HIV (PWHIV) and HIV incidence trends. . . Methods. We used routine laboratory data to inform a biomarker model of time since …
Eurosurveillance latest updates
11.10.2024
…C sequences correlated with an earlier weighted mean date of COVID-19 deaths. . . Conclusion. Community transmission in Sweden started when mitigation efforts still focused on preventing influx. This created a transmission advantage for clade 20C, likely introduced from ongoing cryptic spread in Austria. Therefore, pandemic preparedness should have a comprehensive approach, including capacity for large-scale diagnostics to allow early detection of travel-related cases and community transmission. . . .
Eurosurveillance latest updates
20.09.2024
. Background. In the Netherlands, HIV pre-exposure prophylaxis (PrEP) has been available since 2019. However, the extent of PrEP use prior to HIV diagnosis and development of PrEP-resistance-associated mutations (RAMs) is not known. . . Aim. We assessed prior PrEP use and potential transmission of PrEP RAMs among men who have sex with men (MSM) and transgender persons (TGP) with a new HIV diagnosis in the Netherlands. . . Methods. Data on prior PrEP use between 1 January 2018 and 31 December 2022 were…