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Søgning på udtrykket 'shock' giver 47 resultater
Dokumenter [2] Sider [4] Nyt fra tidsskrifterne [+20] Aktuelle smitsomme sygdomme [+20]
Dokumenter [2]
Disse rekommandationer retter sig mod voksne indlagt med mistænkt sepsis og septisk shock. Se flowchart på infmed.dk/bilag#sepsis_flowchart_(2021).pdf
Bilag med flowchart til vurdering og behandling af sepsis og septisk shock, se også infmed.dk/guidelines#sepsis_guidelines_(2021).pdf
Sider [4]
[…] Dis 2015;15:1–7. 7. Hirst C, Owusu-Ofori S. Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease. Cochrane Database Syst Rev 2014;11:CD003427. 8. Falletta JM, Woods GM, Verter JI, m.fl. Discontinuing penicillin prophylaxis in children with sickle cell anemia. Prophylactic Penicillin Study II. J Pediatr 1995;127:685–90. 9. El-Alfy MS, El-Sayed MH. Overwhelming postsplenectomy infection: Is quality of patient knowledge enough for prevention? Hematol J […]
[…] praksis. Afdelingslæge, Jon Gitz Holler, Nordsjællands Hospital. 12. juni 2024 (dag 2) Sepsis, antibiotika, urinvejsinfektioner Tid Emne og underviser 08.30 – 12.30 SEPSIS 08.30 – 09.30 Det septiske shock. Professor, overlæge Anders Perner, Intensiv, RH. 09.30 – 09.45 Pause 09.45 – 10.30 Definition og behandling af sepsis I. Overlæge Christian Fischer, Infektionsmedicin, Hvidovre. 10.30 – 10.45 Pause 10.45 – 11.30 Definition og behandling af sepsis II. Overlæge Christian Fischer, […]
[…] urin til D+R Afhængig af klinik: CT-cerebrum EEG (NCSE) Ekkokardografi ØNH-tilsyn Understøttende behandling Volumen og elektrolyt terapi Smerter/Kramper Indikation for intensiv terapi Ved sepsis eller septisk shock anvendes isoton NaCl (0,9 %) som infusionsvæske. Ved hyponatriæmi og bevidsthedspåvirkning se** Giv ikke væsker som bliver hypotone efter indgift (Ringer, Na-K-Glukose eller Glukose), da risikoen for hjerneødem øges. Smertebehandling: paracetamol 1 g x 4 evt + morfin 10 mg x 3-4 Kramper: inj. […]
[…] urin til D+R Afhængig af klinik: CT-cerebrum EEG (NCSE) Ekkokardografi ØNH-tilsyn Understøttende behandling Volumen og elektrolyt terapi Smerter/Kramper Indikation for intensiv terapi Ved sepsis eller septisk shock anvendes isoton NaCl (0,9 %) som infusionsvæske. Ved hyponatriæmi og bevidsthedspåvirkning se** Giv ikke væsker som bliver hypotone efter indgift (Ringer, Na-K-Glukose eller Glukose), da risikoen for hjerneødem øges. Smertebehandling: paracetamol 1 g x 4 evt + morfin 10 mg x 3-4 Kramper: inj. […]
Professor Court Petersen kommenterer: Velskreven oversigtsartikel, der bør læses af alle, der har med sepsispatienter at gøre. Artiklen 'afliver' det noget forældede SIRS begreb. Andre 2013-artikler fra NEJM kan med stor fordel læses som supplement: 'Circulatory shock' N Engl J Med. 2013;369(18):1726-34 'Resuscitation fluids' N Engl J Med. 2013;369(13):1243-51 'Ventilator-induced lung injury' N Engl J Med. 2013;369(22):2126-36
Nyt fra tidsskrifterne [+20]
Der er mere end 20 resultater, måske du vil se flere resultater her?
BMC Infectious Diseases
25. oktober 2025
[…] and purpose Treating septic shock requires a multifactorial plan, such as anti-inflammatory drugs and newer drugs to reduce inflammation. This study investigated the effect of a combination (statin and vitamin C) on septic shock mortality and disease symptoms. Methods In this double-blind clinical trial study, 60 patients with septic shock hospitalized in the intensive care unit were assigned into two groups: intervention (1 gram of vitamin C was prescribed once a day for 5 days, and […]
Critical Care Medicine
24. oktober 2025
[…] 30-day follow-up. Allocation was stratified according to trial site and presence of chronic arterial hypertension. Setting: Three European university hospital ICUs with enrollment from 2016 to 2022. Patients: Two hundred nineteen patients with septic shock and blood lactate greater than 3 mmol/L allocated to TTP (n = 111) vs. SC (n = 108). Interventions: The TTP protocol comprised capillary refill time, peripheral skin temperature, arterial lactate concentrations, and MAP 50–65 mm Hg. The SC protocol […]
BMJ Open
22. oktober 2025
[…] is a lack of evidence on the efficacy of extracorporeal blood purification (EBP) to reduce the mortality rate in septic shock. We have designed the EABPSS (Efficacy of Adaptive Blood Purification for Septic Shock) study to confirm whether adaptive blood purification (ABP) intervention could confer a clinical benefit. Methods and analysisIn this multicentre, open-label, randomised controlled trial, we are recruiting a total of 276 patients with septic shock. Eligible patients who provide […]
Neutropenic sepsis and septic shock in ICU patients: A single-center experience over the last decade
PLoS One Infectious Diseases
15. oktober 2025
[…] Florian Guillotin, Laetitia Aubert, Soraya Benguerfi, Reyes Munoz Calahorro, Alice Vennier, David Boutoille, Thomas Gastinne, Jean Reignier, Jean-Baptiste Lascarrou, Matilde Karakachoff, Emmanuel Canet Purpose Sepsis and septic shock in patients with neutropenia are associated with high mortality. We investigated the features and outcome predictors of neutropenic sepsis in the last decade. Methods Consecutive patients who were admitted to the intensive care unit (ICU) of a French university-affiliated […]
Critical Care Medicine
30. september 2025
[…] strategy might decrease organ dysfunction compared with a liberal extracorporeal oxygenation strategy. Design: Pilot multicenter randomized controlled trial. Setting: Four ICUs in three teaching hospitals of the eastern France. Patients: Cardiogenic shock supported by venoarterial extracorporeal membrane oxygenation (VA ECMO). Interventions: FDO2 titration targeting postoxygenator oxygen partial pressure (PPOSTO2) 100–150 mm Hg in the conservative arm, and FDO2 maintained at 100% in the liberal arm. […]
BMC Infectious Diseases
27. september 2025
[…] To assess whether continuous infusion of β-lactam antibiotics improves clinical outcomes compared to intermittent infusion in adult patients with sepsis or septic shock. Methods We conducted a systematic review and meta-analysis of randomized controlled trials comparing continuous versus intermittent β-lactam infusion. Databases searched included PubMed, Scopus, Web of Science, and Embase. Risk of bias was assessed using the RoB 2.0 tool, and the certainty of evidence was evaluated using GRADE. […]
Critical Care Explorations
25. september 2025
[…] OBJECTIVE: We explored the association between PMX-HP and clinical outcomes in patients in ICUs. DESIGN, SETTING, AND PARTICIPANTS: This is a multicenter prospective cohort study conducted in 20 ICUs in Japan between 2020 and 2022. Patients with septic shock requiring high-dose norepinephrine (≥ 0.2 µg/kg/min) were included. MAIN OUTCOMES AND MEASURES: We compared patient characteristics and outcomes between those who received PMX-HP (PMX group) and those who did not (non-PMX group). A primary outcome […]
BMJ Open
19. september 2025
[…] study aims to define the prevalence of Do-Not-Resuscitate (DNR) orders among patients with shock in the emergency department (ED) and explore their impact on clinical management and mortality outcomes. DesignA retrospective observational cohort study was conducted involving patients presenting to the ED with shock. SettingAn ED in a tertiary hospital in western China. Participants2001 patients (aged ≥18 years) presenting to the ED with shock from 1 January 2022 to 31 December 2023. MethodsThe […]
Critical Care Explorations
17. september 2025
[…] Guidelines recommend hydrocortisone as an adjunctive treatment in septic shock, but the optimal dosing regimen is unknown. A national shortage of hydrocortisone in 2023 prompted a change in institutional practice for hydrocortisone administration from 50 mg every 6 hours to 100 mg every 12 hours in an effort to reduce waste and conserve vials, creating an opportunity to evaluate the comparative effectiveness of these two regimens. The primary efficacy outcome was time to shock resolution, and […]
Critical Care Explorations
17. september 2025
[…] To determine the impact of using dynamic measures of fluid responsiveness in guiding the resuscitation of adult patients with sepsis and septic shock. DATA SOURCE: We searched MEDLINE, Embase, and unpublished sources from inception to February 3, 2025. STUDY SELECTION: We included randomized controlled trials (RCTs) that evaluated the use of dynamic measures of fluid responsiveness to guide resuscitation compared with any other method in patients with sepsis and septic shock. DATA EXTRACTION: We […]
Infection
6. september 2025
[…] cerebrospinal fluid and blood by next-generation sequencing, and was cultured from sputum. The isolate was resistant to erythromycin, clindamycin, and tetracycline. By genomic analysis, the isolate was identified to be emm12 of global Clade II and harbor mobile genetic elements of ICE-emm12 and ΦHKU.vir, carrying resistance genes ermB and tetM. We report a fatal case of meningitis case complicated with streptococcal toxic shock syndrome caused by emm12 S. pyogenes in China, which is rare in this […]
Critical Care Explorations
31. august 2025
[…] patients at higher risk of death from sepsis and determine the relationship to previously described sepsis phenotypes. DESIGN, SETTING, AND PARTICIPANTS: Prospective observational study in four ICUs enrolling critically ill patients with septic shock. MAIN OUTCOMES AND MEASURES: Endotoxin activity assay (EAA) results, Sequential Organ Failure Assessment (SOFA), and multiple organ dysfunction (MODS) and 28-day mortality. RESULTS: We enrolled 90 patients aged 25–95 years and set an EAA cutoff of […]
Critical Care Explorations
31. august 2025
[…] Vasopressin is used in one-third of patients with septic shock to augment hemodynamics and reduce overall catecholamine exposure. However, the optimal clinical context in which to initiate vasopressin is unknown. OBJECTIVES: To determine the association between norepinephrine-equivalent dose, lactate concentration, and time duration from shock onset at vasopressin initiation with in-hospital mortality DESIGN, SETTING, AND PARTICIPANTS: Retrospective, observational evaluation utilizing Medical […]
PLoS One Infectious Diseases
30. august 2025
[…] Žiga Kalamar, Mario Gorenjak, Giovanni Landoni, Andrej Markota Introduction The main mechanism of hypotension in septic shock is persistent vasodilation secondary to vascular hyporeactivity despite high endogenous catecholamine levels and despite endogenous activation of the renin-angiotensin-aldosterone system. The classic stepwise approach involves initiation of norepinephrine, up-titration of the dosage to achieve a specified mean arterial pressure and moving to a second-line vasopressor if the […]
JAMA
19. august 2025
[…] the Editor As intensivists and data scientists, we were delighted to read the recent Optimal Vasopressin Initiation in Septic Shock (OVISS) reinforcement learning study. Although this innovative study demonstrates the potential of artificial intelligence (AI) integration to save lives with timely, personalized treatment recommendations, we were disappointed that the model’s code was not released with the article. Most health care AI models are never externally validated or used in practice, and most […]
JAMA
19. august 2025
In Reply We thank Drs Gao and Parker for their insightful comments on our recent study. We fully agree with the crucial importance of open science. As highlighted, sharing key portions of the code architecture is an essential step to enable dissemination, foster exploration of the transportability of the results to different settings, and, in some cases, support adaptation of the model to improve local performance.
Critical Care Medicine
9. august 2025
[…] To determine whether low-density lipoprotein cholesterol (LDL-C) levels, set by the balance of clearance and production, causally contribute to septic shock 28-day mortality. Design: We measured LDL-C levels and genotypes in patients with septic shock. Using Genotyping and Genome-Wide Association Study summary statistics from over 150,000 Japanese participants, we genetically predicted pre-infection LDL-C levels. Two-sample Mendelian randomization was used to assess the causal relationship […]
PLoS One Infectious Diseases
8. august 2025
[…] uncertainty increases, financial institutions experience higher inefficiencies, reflected in increased NPLs, and with proper management solutions, the economy can move toward sustainability. This research analyzes the effect of severe macroeconomic shocks on the NPLs of the Iranian banking system using the Time-Varying Parameter Vector Autoregressions (TVP-VAR) model and a Panel Data Model. The study utilizes data from 2007 to 2021 on key macroeconomic indicators such as economic growth rate, […]
BMJ Open
2. august 2025
[…] ill patients often require enteral nutrition, but the optimal feeding strategy—continuous or intermittent—remains uncertain. While continuous enteral nutrition ensures steady nutrient delivery, it may inhibit key metabolic and cellular processes such as autophagy and ketogenesis. Intermittent enteral nutrition, by mimicking fasting periods, could activate protective pathways, potentially improving clinical outcomes. However, evidence for its efficacy and safety in intensive care […]
BMC Infectious Diseases
31. juli 2025
[…] The relationship between the anion gap (AG) level, represented by the time-weighted average AG (TWA-AG), and outcomes of septic shock patients remains unclear. This study aimed to investigate the relationship between TWA-AG and all-cause mortality in septic shock patients. Methods This study included septic shock patients from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database. Participants were categorized into four quartiles based on their TWA-AG values. The primary outcome […]
Aktuelle smitsomme sygdomme [+20]
Der er mere end 20 resultater, måske du vil se flere resultater her?
Medscape Infectious Diseases
26. juli 2025
Despite strong clinical data, RSV immunization rates among pregnant women and older adults remain worryingly low, highlighting the need for targeted outreach programs. Medscape Medical News
Medscape Infectious Diseases
10. juli 2025
In this edition of Medicine Matters, Dr Sandra Fryhofer, breaks down the June ACIP meeting — RSV and COVID vaccines votes, the omission of HPV, and misleading information about thimerosal. Medscape Internal Medicine
Medscape Infectious Diseases
25. april 2025
The VASST trial was first published in 2008 and has spawned 16 years of analysis and debate. Aaron Holley, MD, has vacillated on whether early vasopressin is the right call, but now he\'s all in. Medscape Critical Care
ProMED
4. marts 2025
[…] TOXIC SHOCK SYNDROME - JAPAN******************************************A ProMED-mail postwww.promedmail.orgProMED-mail is a program of theInternational Society for Infectious Diseaseswww.isid.org Date: Mon 24 Feb 2025 Source: Emerging Infectious Diseases [edited] wwwnc.cdc.gov/eid/article/31/4/24-1076_article Citation: Ujiie M. Emerging trends in streptococcal toxic shocksyndrome, Japan. Emerg Infect Dis. 2025;31(4).doi.org/10.3201/eid3104.241076 […]
ProMED
26. februar 2025
[…] - VIET NAM: (CA MAU) CONGENITAL, PREVENTION, ANAPHYLACTICSHOCK, FATAL*******************************************************************************A ProMED-mail postwww.promedmail.orgProMED-mail is a program of theInternational Society for Infectious Diseaseswww.isid.org Date: Mon 24 Feb 2025 Source: Tuoi Tre News [in Vietnamese, machine trans., edited] tuoitrenews.vn/news/society/20250224/in-vietnam-newborn-dies-after-receiving-penicillin-shot-to-prevent-syphilis/84773.html […]
ProMED
15. februar 2025
[…] DISEASE - VIET NAM: SEPTIC SHOCK, FATAL*****************************************************A ProMED-mail postwww.promedmail.orgProMED-mail is a program of theInternational Society for Infectious Diseaseswww.isid.org Date: Thu 13 Feb 2025 Source: VN Express [in Vietnamese, machine trans., edited] vnexpress.net/mot-quan-nhan-tu-vong-do-nhiem-khuan-nao-mo-cau-4849299.html A soldier died of meningococcal infection ----------------------------------------- Soldier [N. V. […]
Medscape Infectious Diseases
11. juli 2025
The ACIP shakeup sent shockwaves through the public health system. Dr Sandra Fryhofer unpacks the fallout of this decision and what it means for the future of vaccine policy. Medscape Internal Medicine
WHO Eastern Mediterranean Region news
27. april 2025
[…] six high-burden countries: Afghanistan, Djibouti, Pakistan, Somalia, Sudan, and Yemen. While malaria is receding in many parts of the world, our Region is facing a troubling rise in cases―driven by conflict, fragile health systems, climate-related shocks, and the increasing risk of resistance to drugs and insecticides. Between 2015 and 2023, the estimated malaria incidence in the Region more than doubled to 17.9 cases per 1,000 people at risk. But we are making progress. In 2024, WHO supported the […]
ProMED
15. april 2025
[…] poisoning of 3 minors and 1 adult last weekend inBogotá has been identified, resulting in the deaths of 2 of theminors. The girls died on 5 and 10 Apr 2025, respectively, while receivingmedical careat the Santa Fe Foundation. The incident has caused shockin the community; however, authorities clarified these were isolatedincidents and there is no evidence to suggest a public healthconcern. According to information published by \'Semana\', the deceased minorsand the other 2 victims were reportedly […]
ProMED
15. april 2025
[…] days with symptoms of sudden high fever, headache, vomiting,and impaired consciousness. At that time, the patient quickly becomescomatose, with necrotic hemorrhagic rashes appearing on the skin inthe context of acute adrenal insufficiency syndrome, shock, and rapiddeath. To prevent meningococcal disease, people should practice good personalhygiene and hygiene in their living quarters, wear masks when incontact with or caring for sick people, and take preventive medicine.In particular, the most […]
ProMED
8. april 2025
[…] same type of bacteria, group A _Streptococcus_, is responsible forstrep throat -- a far milder infection. Invasive streptococi cantrigger necrotizing fasciitis, a soft tissue infection also known asflesh-eating disease, or streptococcal toxic shock syndrome, an immunereaction akin to sepsis that can lead to organ failure. \'Within 24 to 48 hours, you could have very, very rapiddeterioration,\' said Dr. Victor Nizet, a professor of pediatrics atthe University of California, San Diego. Cases can […]
ProMED
3. april 2025
[…] fever. Initial symptoms of yellow fever can include fever, chills, severeheadache, back pain, general body aches, nausea, vomiting, fatigue(feeling tired), and weakness. Severe symptoms include high fever,yellow skin or eyes (jaundice), bleeding, shock, and organ failure. Ifyou think you or a family member might have yellow fever, see a doctoror talk with a healthcare provider. Visit the US Centers for Disease Control and Prevention (CDC) […]
ProMED
3. april 2025
[…] can lead to poisoning for buyers who drink it. When ingested, methanol can turn into a toxic substance that affectsmany organs. This substance can cause damage to the central nervoussystem, acute respiratory failure, heart failure, hypotension, severeshock, acute kidney failure, blindness, etc. Treatment is oftendifficult, with a high mortality rate. Doctors recommend choosing alcohol with a clear origin and ensuringfood safety to drink. Be alert when experiencing fatigue, headache,especially blurred […]
ProMED
25. marts 2025
[…] is associated with better outcomes. The study,published this week [19 Mar 2025] in JAMA Network Open, found thatsepsis patients who received care that was noncompliant with theCenters for Medicare and Medicaid Services (CMS) Severe Sepsis andSeptic Shock Management Bundle (SEP-1) tended to be older, have morecomorbidities, and have more complex clinical presentation than thosewho received compliant care. When those factors were accounted for,SEP-1 compliance was no longer associated with improved […]
ProMED
25. marts 2025
[…] of India [edited] timesofindia.indiatimes.com/life-style/health-fitness/health-news/woman-in-delhi-ncr-dies-of-rabies-days-after-drinking-milk-from-infected-cow-report/articleshow/119330439.cms A strange case from Delhi NCR\'s Greater Noida has shocked everyone. Asper reports, a woman residing in Greater Noida succumbed to rabiesafter contracting the infection via cow milk. The reports have saidthat the cow had rabies after being bitten by a stray dog. While a few people from the nearby area […]
ProMED
25. marts 2025
[…] do not eat blood pudding or slaughter pigs but still getsick. The cause is eating raw infected pork, or coming into contactwith infected pigs through skin lesions or scratches duringprocessing. In severe cases, the disease can progress rapidly to septic shock,circulatory collapse, hypotension, severe blood clotting disorders,hemorrhagic necrosis, embolism, multiple organ failure, coma anddeath. Many people think that if they do not eat pig blood pudding, they canswitch to eating poultry blood pudding […]
ProMED
25. marts 2025
[…] disturbance - Stress: transportation, social, nutritional - Gastrointestinal disturbance: motility (especially colic), feedchange Clinical signs of salmonellosis include diarrhea, fever, lethargy,anorexia, colic, localized infection, sepsis and septic shock. Foalsare commonly more seriously affected with profound systemic illness,including hemorrhagic diarrhea, pneumonia, meningitis, inflammation ofgrowth plate and septic arthritis. Treatment of the severe form of salmonellosis is based on IV fluid […]
ProMED
17. marts 2025
[…] and was rushed to the hospital when the first signs of theillness were detected on Friday [7 Mar 2025]. However, her health deteriorated rapidly, leading to severecardiovascular and respiratory complications that caused refractoryshock. Sadly, she died on Sunday [9 Mar 2025]. In response to this tragic event, health authorities immediatelyactivated preventive isolation protocols for those people who hadclose contact with the victim. Isolation of close contacts […]
ProMED
13. marts 2025
[…] with the \'flesh-eating bacteria\' _Vibrio vulnificus_. This type of bacteria lives in saltwater, brackish water orparasitized shrimp and oysters, can cause blood infection and tissuenecrosis with high mortality rate, up to 50%, even 90% if septic shockoccurs. Previously, the patient worked as a ship driver, was healthy, and hadno underlying medical conditions. After the fall, he treated the woundhimself by applying a plaster and rubbing oil without going to amedical facility. Four days later, his […]
ProMED
12. marts 2025
[…] the death of sheep in herds. More than 20sheep died in half an hour in Kerala Thanda, Mundargi taluk, Gadagdistrict. Anthrax infection is suspected. A herd of 60 sheep has lost 20 of them. A herd of sheep belonging to[PL] have died. The shepherds are shocked to see the death of thesheep. Animal Husbandry Department officials rushed to the spot and conductedan inspection. They have expressed suspicion of anthrax infection.Doctors said that the sheep are dying due to bleeding from their noses(a serious […]