Søgeord (pneumoni) valgt.
51 emner vises.
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Communicable disease threats report, 26 November - 2 December 2023, week 48
ECDC
ECDC Communicable Disease Threats Report, 2.12.2023
Tilføjet 2.12.2023
This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 19 - 25 November 2023 and includes updates on human infection with influenza A(H1N2)v, influenza A(H5N1), an overview of respiratory virus epidemiology in the EU/EEA, respiratory infections due to Mycoplasma pneumoniae in the EU/EEA, HIV/AIDS surveillance 2023 (2022 data), West Nile virus, SARS-CoV-2 variant classification, and poliomyelitis.
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Communicable disease threats report, 26 November - 2 December 2023, week 48
ECDC
ECDC COVID-19 updates, 1.12.2023
Tilføjet 1.12.2023
This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 19 - 25 November 2023 and includes updates on human infection with influenza A(H1N2)v, influenza A(H5N1), an overview of respiratory virus epidemiology in the EU/EEA, respiratory infections due to Mycoplasma pneumoniae in the EU/EEA, HIV/AIDS surveillance 2023 (2022 data), West Nile virus, SARS-CoV-2 variant classification, and poliomyelitis.
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Der er epidemi med mycoplasma-infektioner - også kendt som kold lungebetændelse
Statens Serum Institut, 29.11.2023
Tilføjet 29.11.2023
Der har siden sommeren været en stigning i antallet af luftvejsinfektioner med Mycoplasma pneumoniae, og forekomsten har nu nået et epidemisk niveau med væsentlig flere tilfælde end normalt.
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Emergence and persistent spread of carbapenemase-producing Klebsiella pneumoniae high-risk clones in Greek hospitals, 2013 to 2022
Kyriaki Tryfinopoulou, Marius Linkevicius, Olga Pappa, Erik Alm, Kleon Karadimas, Olov Svartström, Michalis Polemis, Kassiani Mellou, Antonis Maragkos, Alma Brolund, Inga Fröding, Sophia David, Alkiviadis Vatopoulos, Daniel Palm, Dominique L Monnet, Theoklis Zaoutis, Anke Kohlenberg and Greek CCRE study group
Eurosurveillance latest updates, 24.11.2023
Tilføjet 24.11.2023
BackgroundPreliminary unpublished results of the survey of carbapenem- and/or colistin-resistant Enterobacterales (CCRE survey) showed the expansion of carbapenemase-producing Klebsiella pneumoniae (CPKP) sequence type (ST) 39 in 12 of 15 participating Greek hospitals in 2019. AimWe conducted a rapid survey to determine the extent of spread of CPKP high-risk clones in Greek hospitals in 2022 and compare the distribution of circulating CPKP clones in these hospitals since 2013. MethodsWe analysed whole genome sequences and epidemiological data of 310 K. pneumoniae isolates that were carbapenem-resistant or ‘susceptible, increased exposure’ from Greek hospitals that participated in the European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE, 2013–2014), in the CCRE survey (2019) and in a national follow-up survey (2022) including, for the latter, an estimation of transmission events. ResultsFive K. pneumoniae STs including ST258/512 (n = 101 isolates), ST11 (n = 93), ST39 (n = 56), ST147 (n = 21) and ST323 (n = 13) accounted for more than 90% of CPKP isolates in the dataset. While ST11, ST147 and ST258/512 have been detected in participating hospitals since 2013 and 2014, KPC-2-producing ST39 and ST323 emerged in 2019 and 2022, respectively. Based on the defined genetic relatedness cut-off, 44 within-hospital transmission events were identified in the 2022 survey dataset, with 12 of 15 participating hospitals having at least one within-hospital transmission event. ConclusionThe recent emergence and rapid spread of new high-risk K. pneumoniae clones in the Greek healthcare system related to within-hospital transmission is of concern and highlights the need for molecular surveillance and enhanced infection prevention and control measures.
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Emergence and rapid dissemination of highly resistant NDM-14-producing Klebsiella pneumoniae ST147, France, 2022
Cécile Emeraud, Aba Mahamat, Agnès B. Jousset, Sandrine Bernabeu, Tania Goncalves, Camille Pommier, Delphine Girlich, Aurélien Birer, Christophe Rodriguez, Jean-Michel Pawlotsky, Thierry Naas, Rémy A. Bonnin and Laurent Dortet
Eurosurveillance latest updates, 20.10.2023
Tilføjet 20.10.2023
BackgroundSince 2021, an emergence of New Delhi metallo-β-lactamase (NDM)-14-producing Klebsiella pneumoniae has been identified in France. This variant with increased carbapenemase activity was not previously detected in Enterobacterales. AimWe investigated the rapid dissemination of NDM-14 producers among patients in hospitals in France. MethodsAll NDM-14-producing non-duplicate clinical isolates identified in France until June 2022 (n = 37) were analysed by whole genome sequencing. The phylogeny of NDM-14-producers among all K. pneumoniae sequence type (ST) 147 reported in France since 2014 (n = 431) was performed. Antimicrobial susceptibility testing, conjugation experiments, clonal relationship and molecular clock analysis were performed. ResultsThe 37 NDM-14 producers recovered in France until 2022 belonged to K. pneumoniae ST147. The dissemination of NDM-14-producing K. pneumoniae was linked to a single clone, likely imported from Morocco and responsible for several outbreaks in France. The gene blaNDM-14 was harboured on a 54 kilobase non-conjugative IncFIB plasmid that shared high homology with a known blaNDM-1-carrying plasmid. Using Bayesian analysis, we estimated that the NDM-14-producing K. pneumoniae ST147 clone appeared in 2020. The evolutionary rate of this clone was estimated to 5.61 single nucleotide polymorphisms per genome per year. The NDM-14 producers were highly resistant to all antimicrobials tested except to colistin, cefiderocol (minimum inhibitory concentration 2 mg/L) and the combination of aztreonam/avibactam. ConclusionHighly resistant NDM-14 producing K. pneumoniae can rapidly spread in healthcare settings. Surveillance and thorough investigations of hospital outbreaks are critical to evaluate and limit the dissemination of this clone.
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Rapid spread of a novel NDM-producing clone of Klebsiella pneumoniae CC147, Northern Italy, February to August 2023
Irene Mileto, Greta Petazzoni, Marta Corbella, Stefano Gaiarsa, Cristina Merla, Angela Kuka, Marina Ramus, Cristina Terulla, Micaela Brandolini, Antonio Piralla, Patrizia Cambieri and Fausto Baldanti
Eurosurveillance latest updates, 20.10.2023
Tilføjet 20.10.2023
New Delhi metallo-beta-lactamase (NDM)-producing Klebsiella pneumoniae (Kp) ST147 caused a large multi-hospital outbreak in Italy from 2018 to 2021. We describe a new ST6668 NDM-producing Kp clone, belonging to CC147, which rapidly spread across hospitals in the Pavia province (Northern Italy) from February to August 2023. Genomic analyses revealed that ST6668 is different from ST147 and fast evolving. As shown here, genomic surveillance programmes are useful for tracking the spread of new clones with reduced susceptibility to most antibiotics.
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Pneumonia, Not Just Inflammation, May Cause Severe COVID
Medscape Infectious Diseases, 26.09.2023
Tilføjet 26.09.2023
New research from Northwestern University and the University of Wisconsin, however, is pointing to bacterial pneumonia as the cause of many severe COVID deaths. WebMD Health News
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Worm Pulled From Woman's Brain in Case That 'Stunned'
Medscape Infectious Diseases, 22.09.2023
Tilføjet 22.09.2023
A 64-year-old woman diagnosed with pneumonia had abdominal pain, diarrhea, dry cough, and night sweats. A year of inexplicable symptoms ended in an open biopsy and a live, stringlike worm. Medscape Medical News
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Three Cases of Community-Acquired Pneumonia
Medscape Infectious Diseases, 19.09.2023
Tilføjet 19.09.2023
Clinicians should consider all three etiologies on community-acquired pneumonia presentation to improve antimicrobial stewardship and patient outcomes. CDC Expert Commentary
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Sustained increase of paediatric invasive Streptococcus pyogenes infections dominated by M1UK and diverse emm12 isolates, Portugal, September 2022 to May 2023
Catarina Gouveia, Maria Paula Bajanca-Lavado, Rafael Mamede, Ana Araújo Carvalho, Fernanda Rodrigues, José Melo-Cristino, Mario Ramirez, Ana Friães, Portuguese Group for the Study of Streptococcal Infections and Portuguese Study Group of Pediatric Invasive Streptococcal Disease
Eurosurveillance latest updates, 8.09.2023
Tilføjet 8.09.2023
Since autumn 2022, observed numbers of paediatric invasive group A Streptococcus infections in Portugal (n = 89) were higher than in pre-COVID-19 seasons. Between September 2022 and May 2023, the dominant diagnoses were pneumonia (25/79), mostly with empyema (20/25), and sepsis (22/79). A number of cases required admission to intensive care (27/79) and surgery (35/79), and the case fatality rate was 5.1% (4/79). Genomic sequencing (n = 55) revealed multiple genetic lineages, dominated by the M1UK sublineage (26/55) and more diverse emm12 isolates (12/55).
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A Q fever outbreak among visitors to a natural cave, Bizkaia, Spain, December 2020 to October 2021
Ana Hurtado, Ion I Zendoia, Eva Alonso, Xabier Beraza, Joseba Bidaurrazaga, Blanca Ocabo, Iñaki Arrazola, Aitor Cevidanes, Jesús F Barandika and Ana L García-Pérez
Eurosurveillance latest updates, 14.07.2023
Tilføjet 14.07.2023
We describe a large Q fever outbreak reported in Spain, including 108 cases, 53 with pneumonia and 27 requiring hospitalisations. The first cases were detected in February 2021 among rock climbers visiting a cave in Bizkaia, and the last case was detected in October 2021. Most cases were notified after the Easter holiday (April–May 2021). More males (63.9%) than females (36.1%) were infected (median ages: 42 (1–68) and 39 years (6–61), respectively). We detected Coxiella burnetii by PCR in faecal, dust and/or aerosol samples taken inside the cave in March 2021, and in dust and aerosol samples collected between March 2021 and February 2023. Coxiella burnetii from dust samples were cultured on Vero cells, showing viability for 24 months. Based on serological and genotyping data, goats sheltering in the cave were the most likely source of infection. The cave was closed on 29 April 2021, movements of goats and sheep in the area were restricted (March–July 2021), and the animals were vaccinated in October 2021. Investigation of Q fever outbreaks requires a multidisciplinary One Health approach as these outbreaks can occur in unexpected places like natural sites where animals are present.
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Nationwide, population-based observational study of the molecular epidemiology and temporal trend of carbapenemase-producing Enterobacterales in Norway, 2015 to 2021
Oskar Ljungquist, Bjørg Haldorsen, Anna Kaarina Pöntinen, Jessin Janice, Ellen Haldis Josefsen, Petter Elstrøm, Oliver Kacelnik, The Norwegian Study Group on CPE, Arnfinn Sundsfjord and Ørjan Samuelsen
Eurosurveillance latest updates, 7.07.2023
Tilføjet 7.07.2023
IntroductionNational and regional carbapenemase-producing Enterobacterales (CPE) surveillance is essential to understand the burden of antimicrobial resistance, elucidate outbreaks, and develop infection-control or antimicrobial-treatment recommendations. AimThis study aimed to describe CPE and their epidemiology in Norway from 2015 to 2021. MethodsA nationwide, population-based observational study of all verified clinical and carriage CPE isolates submitted to the national reference laboratory was conducted. Isolates were characterised by antimicrobial susceptibility testing, whole genome sequencing (WGS) and basic metadata. Annual CPE incidences were also estimated. ResultsA total of 389 CPE isolates were identified from 332 patients of 63 years median age (range: 0–98). These corresponded to 341 cases, 184 (54%) being male. Between 2015 and 2021, the annual incidence of CPE cases increased from 0.6 to 1.1 per 100,000 person-years. For CPE-isolates with available data on colonisation/infection, 58% (226/389) were associated with colonisation and 38% (149/389) with clinical infections. WGS revealed a predominance of OXA-48-like (51%; 198/389) and NDM (34%; 134/389) carbapenemases in a diversified population of Escherichia coli and Klebsiella pneumoniae, including high-risk clones also detected globally. Most CPE isolates were travel-related (63%; 245/389). Although local outbreaks and healthcare-associated transmission occurred, no interregional spread was detected. Nevertheless, 18% (70/389) of isolates not directly related to import points towards potentially unidentified transmission routes. A decline in travel-associated cases was observed during the COVID-19 pandemic. ConclusionsThe close-to-doubling of CPE case incidence between 2015 and 2021 was associated with foreign travel and genomic diversity. To limit further transmission and outbreaks, continued screening and monitoring is essential.
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Towards One Health surveillance of antibiotic resistance: characterisation and mapping of existing programmes in humans, animals, food and the environment in France, 2021
Lucie Collineau, Clémence Bourély, Léo Rousset, Anne Berger-Carbonne, Marie-Cécile Ploy, Céline Pulcini and Mélanie Colomb-Cotinat
Eurosurveillance latest updates, 2.06.2023
Tilføjet 2.06.2023
BackgroundInternational organisations are calling for One Health approaches to tackle antimicrobial resistance. In France, getting an overview of the current surveillance system and its level of integration is difficult due to the diversity of surveillance programmes. AimThis study aimed to map and describe all French surveillance programmes for antibiotic resistance (ABR), antibiotic use (ABU) and antibiotic residues, in humans, animals, food and the environment, in 2021. Another objective was to identify integration points, gaps and overlaps in the system. MethodsWe reviewed the literature for surveillance programmes and their descriptions. To further characterise programmes found, semi-directed interviews were conducted with their coordinators. ResultsIn total 48 programmes in the human (n = 35), animal (n = 12), food (n = 3) and/or the environment (n = 1) sectors were identified; 35 programmes focused on ABR, 14 on ABU and two on antibiotic residues. Two programmes were cross-sectoral. Among the 35 ABR programmes, 23 collected bacterial isolates. Bacteria most targeted were Escherichia coli (n = 17 programmes), Klebsiella pneumoniae (n = 13), and Staphylococcus aureus (n = 12). Extended-spectrum beta-lactamase-producing E. coli was monitored by most ABR programmes (15 of 35) in humans, animals and food, and is a good candidate for integrated analyses. ABU indicators were highly variable. Areas poorly covered were the environmental sector, overseas territories, antibiotic-resistant-bacterial colonisation in humans and ABU in companion animals. ConclusionThe French surveillance system appears extensive but has gaps and is highly fragmented. We believe our mapping will interest policymakers and surveillance stakeholders. Our methodology may inspire other countries considering One Health surveillance of ABR.
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Clinical epidemiology and case fatality due to antimicrobial resistance in Germany: a systematic review and meta-analysis, 1 January 2010 to 31 December 2021
Maria Rödenbeck, Olaniyi Ayobami, Tim Eckmanns, Mathias W Pletz, Jutta Bleidorn and Robby Markwart
Eurosurveillance latest updates, 19.05.2023
Tilføjet 19.05.2023
BackgroundAntimicrobial resistance (AMR) is of public health concern worldwide. AimWe aimed to summarise the German AMR situation for clinicians and microbiologists. MethodsWe conducted a systematic review and meta-analysis of 60 published studies and data from the German Antibiotic-Resistance-Surveillance (ARS). Primary outcomes were AMR proportions in bacterial isolates from infected patients in Germany (2016–2021) and the case fatality rates (2010–2021). Random and fixed (common) effect models were used to calculate pooled proportions and pooled case fatality odds ratios, respectively. ResultsThe pooled proportion of meticillin resistance in Staphylococcus aureus infections (MRSA) was 7.9% with a declining trend between 2014 and 2020 (odds ratio (OR) = 0.89; 95% CI: 0.886–0.891; p
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PRO/EDR> Meningitis - Iraq (03): (SM,HJ) children, enterovirus & S. pneumoniae, WHO, RFI
ProMED, 13.05.2023
Tilføjet 13.05.2023
Pneumonia -- IraqFollowing a surge in meningitis cases in Halabjah City and Sulaymaniyah governorate since mid-April 2023, an expert team from the World Health Organization (WHO) and the Ministry of Health was deployed to the affected areas to perform a joint epidemiological investigation of the reported cases and develop a swift response plan to curb the transmission of the disease.Preliminary laboratory results from 24 collected samples showed a mixture of bacterial (_Streptococcus pneumoniae_) and viral
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PRO/EDR> Klebsiella pneumoniae - USA (02): (WA) nosocomial, MDR, fatal, RFI
ProMED, 7.05.2023
Tilføjet 7.05.2023
Hospital-Related Infection -- United StatesA bacterial outbreak at Virginia Mason Medical Center in Seattle has sickened 31 patients since October [2022]. Seven of them have since died, but it\'s unknown what caused those deaths -- the infection or the diagnoses that brought them to the hospital in the first place._Klebsiella pneumoniae_ is a bacterium usually found in health care settings, and often resistant to antibiotics. It can cause pneumonia, meningitis, and wound or bloodstream infections.Virginia Mason is working with
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PRO/AH/EDR> Porcine circovirus - USA: swine, vaccine effectiveness
ProMED, 3.05.2023
Tilføjet 3.05.2023
Porcine Circovirus -- United StatesThe latest Swine Disease Reporting System report has some people scratching their heads. For the 1st time in recent memory, porcine circovirus type 2 (PCV2) jumped into the top 10 most-diagnosed diseases list at the Iowa State University Veterinary Diagnostic Lab. At No. 9, it surpassed porcine epidemic diarrhea virus and came in just behind _Mycoplasma hyopneumoniae_.Porcine-circovirus-associated disease (PCVAD) can be caused by any PCV2 strain. When PCVAD 1st showed up in the US in
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PRO/EDR> Meningitis - Nigeria (05): sg C, fatal
ProMED, 30.04.2023
Tilføjet 30.04.2023
Meningitis -- NigeriaBetween 1 Oct 2022 and 16 Apr 2023, Nigeria reported a total of 1686 suspected cases of meningitis, including 124 deaths, for a case fatality ratio (CFR) of 7%.Meningitis is a serious infection of the meninges, the membranes covering the brain and spinal cord. It is a devastating disease and a major public health challenge. _Neisseria meningitidis_ (meningococcus), _Streptococcus pneumoniae_ (pneumococcus), _Haemophilus influenzae_ [serotype b or Hib] and _Streptococcus agalactiae_ (group
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PRO/EDR> Klebsiella pneumoniae - USA: (WA) nosocomial, MDR, fatal, RFI
ProMED, 28.04.2023
Tilføjet 28.04.2023
Klebsiella pneumoniae -- United StatesFour patients at a downtown Seattle hospital are dead in connection to an outbreak of a bacterium often found in healthcare settings that has developed resistance to some antibiotics.The [31] infected patients, who contracted _Klebsiella_, were hospitalized in various departments, including inpatient medical beds, an ICU, and an operating room at Virginia Mason Medical Center, the hospital said in a statement released Wednesday [26 Apr 2023].Beginning in October 2022, hospital staff
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Within-patient horizontal transfer of pOXA-48 from a hypervirulent Klebsiella pneumoniae SL218 to Serratia marcescens following spread of the K. pneumoniae isolate among hospitalised patients, Denmark, 2021
Karen Leth Nielsen, Marc Sørensen, Frederik Boëtius Hertz, Maria Anna Misiakou, Henrik Hasman, Susanne Häussler, Marie Helleberg and Kristian Schønning
Eurosurveillance latest updates, 28.04.2023
Tilføjet 28.04.2023
A hypervirulent Klebsiella pneumoniae SL218 (ST23-KL57), phylogenetically distinct from the classical hypervirulent SL23 (ST23-KL1) lineage, was transmitted between hospitalised patients in Denmark in 2021. The isolate carried a hybrid resistance and virulence plasmid containing blaNDM-1 and a plasmid containing blaOXA-48 (pOXA-48); the latter plasmid was horizontally transferred within-patient to Serratia marcescens. The convergence of drug resistance and virulence factors in single plasmids and in different lineages of K. pneumoniae is concerning and requires surveillance.
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PRO/EDR> Legionellosis - USA (07): (NJ) fatal/Mercer Cty/Trenton Water Works/2020-23, RFI
ProMED, 1.04.2023
Tilføjet 1.04.2023
Legionnaires' -- United StatesThe New Jersey Department of Health is conducting an investigation after 7 people contracted Legionnaire's disease -- and 2 have died -- in areas of Mercer County that are served by Trenton Water Works.In announcing the investigation on Monday [27 Mar 2023], officials said that, between October of last year [2022] and this month [March 2023], 7 people throughout Trenton, Ewing Township, Lawrence Township, and Hamilton Township have contracted the disease -- a type of pneumonia. Of the 7
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PRO/EDR> Meningitis, pneumococcal - Togo: (SA) fatal, RFI
ProMED, 29.03.2023
Tilføjet 29.03.2023
Meningitis - Strep/Pneumoccocal -- TogoIn a follow-up on the meningitis outbreak in Togo, the Togolese Ministry of Health now reports a total of 123 suspected cases of meningitis reported in the Oti Sud district [Savanes region], including 12 deaths, through 19 Mar 2023.The national reference laboratory confirmed the presence of _Streptococcus pneumoniae_ in 17 cases by polymerase chain reaction (PCR) and culture. Nearly 85% of the cases are over 10 years of age, individuals born before the introduction of the pneumococcal
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Tap water as the source of a Legionnaires’ disease outbreak spread to several residential buildings and one hospital, Finland, 2020 to 2021
Eurosurveillance latest updates, 16.03.2023
Tilføjet 18.03.2023
In Finland, all microbiology laboratories notify Legionella findings and physicians notify Legionnaires’ disease (LD) cases to the National Infectious Disease Register. All cases are interviewed, and water samples obtained from potential places of exposure. Legionella isolates from humans and water are compared by whole genome sequencing (WGS). In March 2021, Legionella pneumophila serogroup 1 (Lp 1) pneumonia cases increased in one Finnish city (120,000 inhabitants) where single LD cases are detected annually. We identified 12 LD cases, nine living in different residential buildings and three nosocomial, linked by identical human and/or water isolates. Three of these cases were from January 2020, October 2020 and February 2021 and identified retrospectively. Eleven were diagnosed by urinary antigen test, 10 by PCR and five by culture; age ranged between 52 and 85 years, and 10 had underlying diseases. Nine of 12 homes of LD cases and 15 of 26 water samples from the hospital were positive for Lp 1, with concentrations up to 640,000 cfu/L. Water samples from regional storage tanks were negative. Positivity in homes and the hospital suggested inadequate maintenance measures. Enhanced surveillance combined with WGS was crucial in detecting this unusual LD outbreak related to domestic and hospital water systems.
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PRO/EDR> Legionellosis - USA (05): (OH) nosocomial, RFI
ProMED, 13.03.2023
Tilføjet 13.03.2023
Hospital-Related Infection -- United StatesIncreased water testing protocols are in effect at The Christ Hospital in Mt. Auburn after 3 patients recently tested positive for the presence of _Legionella_, according to a hospital spokesperson._Legionella_ is 'a common organism routinely found in the public water supply,' the spokesperson said late Friday [10 Mar 2023]. It isn't clear whether those patients are diagnosed with Legionnaires' disease, a serious type of pneumonia caused by _Legionella_ bacteria. The hospital has not
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PRO/AH/EDR> Q fever - Croatia: (PG) goat
ProMED, 8.03.2023
Tilføjet 8.03.2023
Q Fever -- A large number of wild [see comment] goats, which have been a long-standing problem for the inhabitants of the small Adriatic island of Unije [of the Cres-Lošinj archipelago] are infected with Q fever.As 'Novi List' writes, tissue samples from dead or shot animals show this, with the note that this infection in humans can cause symptoms similar to flu or pneumonia, and in a small number of cases, damage to the heart, brain, liver, and lungs.According to estimates, there are about 400
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PRO/AH> Equine rhinopneumonitis - Spain: (VC) EHV-1, horse
ProMED, 6.03.2023
Tilføjet 6.03.2023
Equine Herpes Virus -- SpainNine horses are receiving 'close monitoring' in hospital in Valencia, 8 of which are showing neurological signs of equine herpesvirus (EHV-1).H&H reported that the organisers of the Mediterranean Equestrian Tour in Oliva Nova, Spain, had cancelled the 2nd part of the showjumping tour (7-26 Feb [2023]) as 4 horses on-site had tested positive for EHV-1. Ten horses, 6 of whom were showing signs of illness, were put in isolation on 21 Feb [2023]. Swabs were taken, 4 of which were positive, 4
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PRO/AH/EDR> Toxoplasmosis, bighorn sheep - USA: (western)
ProMED, 28.01.2023
Tilføjet 28.01.2023
Toxoplasmosis -- United StatesFisk EA, Cassirer EF, Huggler KS, et al. Abortion and neonatal mortality due to _Toxoplasma gondii_ in bighorn sheep (_Ovis canadensis_). J. Wildl. Dis. 2023; . Epub ahead of print.Bighorn sheep have experienced disease driven impact for several years, and thus the health dimension is a very important aspect of their conservation. Many mortality episodes have been caused by bighorn sheep pneumonia, which is mainly caused by _Mycoplasma ovipneumoniae_ (Movi), an exotic disease agent for
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PRO/AH> Contagious bovine pleuropneumonia - Uganda: (AG) spread
ProMED, 27.01.2023
Tilføjet 27.01.2023
Bovine Pleuropneumonia -- UgandaBovine pleuropneumonia kills 300 cattle in Agago. The disease has been confirmed in 3 sub-counties; Paimol, Laimuto, and Omiya Pachwa, where the majority of farmers were advised to keep their animals in communal kraals [enclosures for cattle or other livestock], to protect them against Karamojong cattle rustlers.--Communicated by:ProMED Rapporteur Mahmoud Orabi['Contagious bovine pleuropneumonia (CBPP) is a disease of cattle and water buffalo caused by _Mycoplasma mycoides_ subsp.
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Molecular surveillance of multidrug-resistant Gram-negative bacteria in Ukrainian patients, Germany, March to June 2022
Eurosurveillance latest updates, 5.01.2023
Tilføjet 6.01.2023
BackgroundSince the beginning of the war in Ukraine in February 2022, Ukrainians have been seeking shelter in other European countries.AimWe aimed to investigate the prevalence and the molecular epidemiology of multidrug-resistant Gram-negative (MDRGN) bacteria and meticillin-resistant Staphylococcus aureus (MRSA) in Ukrainian patients at admittance to the University Hospital Frankfurt, Germany.MethodsWe performed screening and observational analysis of all patients from March until June 2022. Genomes of MDRGN isolates were analysed for antimicrobial resistance, virulence genes and phylogenetic relatedness.ResultsWe included 103 patients (median age: 39 ± 23.7 years), 57 of whom were female (55.3%; 95% confidence interval (CI): 45.2–5.1). Patients were most frequently admitted to the Department of Paediatrics (29/103; 28.2%; 95% CI: 19.7–37.9). We found 34 MDRGN isolates in 17 of 103 patients (16.5%; 95% CI: 9.9–25.1). Ten patients carried 21 carbapenem-resistant (CR) bacteria, five of them more than one CR isolate. Four of six patients with war-related injuries carried eight CR isolates. In six of 10 patients, CR isolates caused infections. Genomic characterisation revealed that the CR isolates harboured at least one carbapenemase gene, blaNDM-1 being the most frequent (n = 10). Core genome and plasmid analysis revealed no epidemiological connection between most of these isolates. Hypervirulence marker genes were found in five of six Klebsiella pneumoniae CR isolates. No MRSA was found.ConclusionHospitals should consider infection control strategies to cover the elevated prevalence of MDRGN bacteria in Ukrainian patients with war-related injuries and/or hospital pre-treatment and to prevent the spread of hypervirulent CR isolates.
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PRO/EDR> Streptococcus, group A update (02): fatal, invasive, children
ProMED, 23.12.2022
Tilføjet 23.12.2022
Strep -- United StatesAbstract---------'Based on a survey sent to 7 Dutch hospitals, we observed a substantial increase in invasive group A streptococcal infections in children in the Netherlands, comparing the pre-COVID-19 pandemic cohort of 2018-2019 to 2021-2022. The most affected age group were children between 0-5 years. Main diagnosis was pneumonia with empyema. Necrotizing fasciitis and streptococcal toxic shock syndrome were also reported in 11% and 7%, respectively. A significant number was admitted to
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PRO/EDR> Legionellosis - USA (17): (NJ) RFI
ProMED, 19.12.2022
Tilføjet 19.12.2022
Legionnaires' -- United StatesCamden County [New Jersey] and state health authorities on Friday [16 Dec 2022] reported a cluster of Legionnaires' disease, a type of pneumonia, in 4 Pennsauken residents.Camden County Health Officer Paschal Nwako said that officials are trying to determine how and where the people got infected so they can prevent further transmission. The source could be outside Pennsauken, he added.One person is hospitalized, while the other 3 are recovering at home, Nwako said. The 1st case was
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Increase in NDM-1 and NDM-1/OXA-48-producing Klebsiella pneumoniae in Germany associated with the war in Ukraine, 2022
Eurosurveillance latest updates, 15.12.2022
Tilføjet 16.12.2022
In 2022, German surveillance systems observed rapidly increasing numbers of NDM-1- and NDM-1/OXA-48-producing Klebsiella pneumoniae, which may in part reflect recurring pre-pandemic trends. Among these cases, however, a presence in Ukraine before diagnosis was frequently reported. Whole genome sequencing of 200 isolates showed a high prevalence of sequence types ST147, ST307, ST395 and ST23, including clusters corresponding to clonal dissemination and suggesting onward transmission in Germany. Screening and isolation of patients from Ukraine may help avoid onward transmission.
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Pneumococcal Vaccine Lowers Hospitalization Risk for Elderly
Medscape Infectious Diseases, 7.12.2022
Tilføjet 7.12.2022
Older adults who received the 13-valent pneumococcal conjugate vaccine were less likely to be hospitalized for pneumonia, a new study found. Medscape Medical News
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PRO/AH/EDR> Aspergillosis - USA: (MN) goose, die-off
ProMED, 1.12.2022
Tilføjet 1.12.2022
Aspergillosis -- United StatesThe Minnesota (MN) Department of Natural Resources has determined the cause of death of the over 100 geese that were found at Loon Lake in Waseca.The DNR says the birds died of pneumonia, pulmonary aspergillosis, which is a fungal disease.The source of the fungal infection is still unknown at the moment, but they said it is unusual for this disease to cause a mass die-off like this.DNR speculates that the weather and fall migration may have made the birds more vulnerable.The
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Antibiotic resistance surveillance of Klebsiella pneumoniae complex is affected by refined MALDI-TOF identification, Swiss data, 2017 to 2022
Eurosurveillance latest updates, 10.11.2022
Tilføjet 11.11.2022
BackgroundModern laboratory methods such as next generation sequencing and MALDI-TOF allow identification of novel bacterial species. This can affect surveillance of infections and antimicrobial resistance. From 2017, increasing numbers of medical microbiology laboratories in Switzerland differentiated Klebsiella variicola from Klebsiella pneumoniae complex using updated MALDI-TOF databases, whereas many laboratories still report them as K. pneumoniae or K. pneumoniae complex.AimOur study explored whether separate reporting of K. variicola and the Klebsiella pneumoniae complex affected the ANRESIS surveillance database.MethodsWe analysed antibiotic susceptibility rates and specimen types of K. variicola and non-K. variicola-K. pneumoniae complex isolates reported by Swiss medical laboratories to the ANRESIS database (Swiss Centre for Antibiotic Resistance) from January 2017 to June 2022.ResultsAnalysis of Swiss antimicrobial resistance data revealed increased susceptibility rates of K. variicola compared with species of the K. pneumoniae complex other than K. variicola in all six antibiotic classes tested. This can lead to underestimated resistance rates of K. pneumoniae complex in laboratories that do not specifically identify K. variicola. Furthermore, K. variicola strains were significantly more often reported from blood and primarily sterile specimens than isolates of the K. pneumoniae complex other than K. variicola, indicating increased invasiveness of K. variicola.ConclusionOur data suggest that refined differentiation of the K. pneumoniae complex can improve our understanding of its taxonomy, susceptibility, epidemiology and clinical significance, thus providing more precise information to clinicians and epidemiologists.
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PRO/AH> Equine rhinopneumonitis - India: (PB) susp, RFI
ProMED, 26.10.2022
Tilføjet 9.11.2022
Equine Herpes Virus -- IndiaGuru Angad Dev Veterinary and Animal Sciences University, Ludhiana, has cautioned horse-rearing farmers against possible outbreak of equine herpesvirus disease in Punjab. For the last 2 months, a large number of horses with nervous form have been presented at the university hospital for the complaint of this disease.The disease is present in almost all the parts of the state with most of the cases being reported from Malwa region of Bathinda, Faridkot, Mukatsar Sahib, Mansa, and Moga,
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PRO/AH/EDR> Contagious bovine pleuropneumonia - Zambia: (CE) cattle, WOAH
ProMED, 31.10.2022
Tilføjet 31.10.2022
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PRO/EDR> Klebsiella pneumoniae - Jamaica: (Kingston) NICU, fatal, RFI
ProMED, 31.10.2022
Tilføjet 31.10.2022
Hospital-Related Infection -- Jamaica
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Nosocomial outbreak by NDM-1-producing Klebsiella pneumoniae highly resistant to cefiderocol, Florence, Italy, August 2021 to June 2022
Marco Coppi , Alberto Antonelli, Claudia Niccolai, Andrea Bartolini, Laura Bartolini, Maddalena Grazzini, Elisabetta Mantengoli, Alberto Farese, Filippo Pieralli, Maria Teresa Mechi, Vincenzo Di Pilato, Tommaso Giani and Gian Maria Rossolini
Eurosurveillance latest updates, 27.10.2022
Tilføjet 28.10.2022
A nosocomial outbreak by cefiderocol (FDC)-resistant NDM-1-producing Klebsiella pneumoniae (NDM-Kp) occurred in a large tertiary care hospital from August 2021–June 2022 in Florence, Italy, an area where NDM-Kp strains have become endemic. Retrospective analysis of NDM-Kp from cases observed in January 2021–June 2022 revealed that 21/52 were FDC-resistant. The outbreak was mostly sustained by clonal expansion of a mutant with inactivated cirA siderophore receptor gene, which exhibited high-level resistance to FDC (MIC ≥ 32 mg/L) and spread independently of FDC exposure.
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PRO/AH/EDR> Pneumonia, bighorn sheep - USA (02): (WY) Mannheimia haemolytica
ProMED, 25.10.2022
Tilføjet 25.10.2022
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Iron Deficiency May Protect Against Bacterial Pneumonia
Medscape Infectious Diseases, 21.10.2022
Tilføjet 21.10.2022
Iron deficiency is the most common nutritional deficiency, but iron is also required for the survival and growth of pathogens, experts say.
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PRO/AH/EDR> Lungworm, cattle - UK: seasonal alert, control
ProMED, 20.10.2022
Tilføjet 21.10.2022
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PRO/AH/EDR> Plague - China (03): (Tibet) pneumonic, fatal
ProMED, 18.10.2022
Tilføjet 18.10.2022
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PRO/AH/EDR> Contagious bovine pleuropneumonia - Namibia (05): (KU) cattle, WOAH
ProMED, 17.10.2022
Tilføjet 17.10.2022
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PRO/AH/EDR> Contagious bovine pleuropneumonia - Namibia (04): (OS) cattle, WOAH
ProMED, 12.10.2022
Tilføjet 12.10.2022
Bovine Pleuropneumonia -- Namibia
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46
Has COVID Swayed the Rise in Pneumococcal Disease in Spain?
Medscape Infectious Diseases, 30.09.2022
Tilføjet 30.09.2022
An increase in the use of two types of antibiotics to treat COVID-19 may have contributed to a rise in antimicrobial-resistant strains of Streptococcus pneumoniae.
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Mysterious Outbreak of Bilateral Pneumonia in Northern Argentina
Medscape Infectious Diseases, 19.09.2022
Tilføjet 20.09.2022
Healthcare workers at a private clinic in the city of San Miguel de Tucumán likely contracted legionellosis, subsequent investigations showed.
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PRO/EDR> Undiagnosed pneumonia - Argentina (04): (TU) fatal, Legionnaires' dis., conf, RFI
ProMED, 6.09.2022
Tilføjet 6.09.2022
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PRO/AH/EDR> Undiagnosed pneumonia - Argentina (03): (TU) fatal, legionnaires' dis., conf., RFI
ProMED, 4.09.2022
Tilføjet 4.09.2022
50
PRO/AH/EDR> Undiagnosed pneumonia - Argentina (02): (TU) fatal, RFI
ProMED, 2.09.2022
Tilføjet 2.09.2022