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Medscape Infectious Diseases, 16.08.2024
Tilføjet 16.08.2024
Pfizer said on Monday its respiratory syncytial virus (RSV) vaccine Abrysvo generated a strong immune response in a late-stage study of four groups of adults aged 18 and... Reuters Health Information
Læs mereMedscape Infectious Diseases, 13.08.2024
Tilføjet 13.08.2024
Correct timing for RSV testing and updated recommendations for three FDA-approved vaccines can reduce adult hospitalizations for this insidious infection. Medscape
Læs mereLea Gur-Arie, Michal Stein, Hanna Sefty, Ilana S Fratty, Ital Nemet, Limor Kliker, Nofar Atari, Neta S Zuckerman, Alina Rosenberg, Heftziba Ivgi, Orit Golan-Shany, Nadav Sorek, Orna Schwartz-Harari, Michal Bromberg, Lital Keinan-Boker, Michal Mandelboim, Aharona Glatman-Freedman and on behalf of the Israeli Respiratory Viruses Hospital Laboratory Network (IRVHLN)
Eurosurveillance latest updates, 9.08.2024
Tilføjet 9.08.2024
BackgroundA new respiratory virus surveillance platform, based on nationwide hospital laboratory data, was established in Israel during the COVID-19 pandemic. AimWe aimed to evaluate the performance of this platform with respect to the detection of influenza and respiratory syncytial virus (RSV) from week 36 in 2020 to week 15 in 2023, and how it fits with the World Health Organization (WHO) mosaic surveillance framework. MethodsData of respiratory samples from hospitalised patients sent for laboratory confirmation of influenza virus or RSV from 25 general hospital laboratories nationwide were collected. We analysed the weekly number and percentage of samples positive for influenza virus or RSV vis-à-vis SARS-CoV-2 activity and compared data from the new surveillance platform with existing surveillance platforms. Using data in the new surveillance platform, we analysed early stages of a 2021 out-of-season RSV outbreak and evaluated the capabilities of the new surveillance system with respect to objectives and domains of the WHO mosaic framework. ResultsThe new hospital-laboratory surveillance platform captured the activity of influenza virus and RSV, provided crucial data when outpatient sentinel surveillance was not operational and supported an out-of-season RSV outbreak investigation. The new surveillance platform fulfilled important objectives in all three domains of the mosaic framework and could serve for gathering additional information to fulfil more domain objectives. ConclusionThe new hospital laboratory surveillance platform provided essential data during the COVID-19 pandemic and beyond, fulfilled important domain objectives of the mosaic framework and could be adapted for the surveillance of other viruses.
Læs mereMorbidity and Mortality Weekly Report (MMWR), 8.08.2024
Tilføjet 8.08.2024
This report describes ACIP recommendations for the use of the RSV vaccine for older adults.
Læs mereEduardo Azziz-Baumgartner, Avital Hirsch, Young M Yoo, Alon Peretz, David Greenberg, Yonat Shemer Avni, Aharona Glatman-Freedman, Michal Mandelboim, Adam MacNeil, Emily T Martin, Gabriella Newes-Adeyi, Mark Thompson, Arnold S Monto, Ran D Balicer, Min Z Levine and Mark A Katz
Eurosurveillance latest updates, 2.08.2024
Tilføjet 2.08.2024
BackgroundHealthcare personnel (HCP) are at high risk for respiratory infections through occupational exposure to respiratory viruses. AimWe used data from a prospective influenza vaccine effectiveness study in HCP to quantify the incidence of acute respiratory infections (ARI) and their associated presenteeism and absenteeism. MethodsAt the start and end of each season, HCP at two Israeli hospitals provided serum to screen for antibodies to influenza virus using the haemagglutination inhibition assay. During the season, active monitoring for the development of ARI symptoms was conducted twice a week by RT-PCR testing of nasal swabs for influenza and respiratory syncytial virus (RSV). Workplace presenteeism and absenteeism were documented. We calculated incidences of influenza- and RSV-associated ARI and applied sampling weights to make estimates representative of the source population. ResultsThe median age of 2,505 participating HCP was 41 years, and 70% were female. Incidence was 9.1 per 100 person-seasons (95% CI: 5.8–14.2) for RT-PCR-confirmed influenza and 2.5 per 100 person-seasons (95% CI: 0.9–7.1) for RSV illness. Each season, 18–23% of unvaccinated and influenza-negative HCP seroconverted. The incidence of seroconversion or RT-PCR-confirmed influenza was 27.5 per 100 person-seasons (95% CI: 17.8–42.5). Work during illness occurred in 92% (95% CI: 91–93) of ARI episodes, absence from work in 38% (95% CI: 36–40). ConclusionInfluenza virus and RSV infections and associated presenteeism and absenteeism were common among HCP. Improving vaccination uptake among HCP, infection control, and encouraging sick HCP to stay home are important strategies to reduce ARI incidence and decrease the risk of in-hospital transmission.
Læs mereECDC
ECDC COVID-19 updates, 29.07.2024
Tilføjet 29.07.2024
This Reporting Protocol describes data collection for influenza, COVID-19, and other respiratory viruses (such as RSV or new viruses of public health concern) in the EU/EEA and wider WHO European Region. Data collection is integrated for most datasets in line with the operational considerations for respiratory virus surveillance in Europe.
Læs mereMedscape Infectious Diseases, 24.07.2024
Tilføjet 24.07.2024
Merck\'s antibody-based shot met the main goal of a mid-to-late stage trial, when tested to protect infants against a disease caused by the respiratory syncytial virus (RSV),... Reuters Health Information
Læs mereMedscape Infectious Diseases, 12.07.2024
Tilføjet 12.07.2024
Important changes to vaccination recommendations for COVID, flu, RSV, and pneumococcal disease -- and what\'s behind the changes -- are summarized here. Medscape Internal Medicine
Læs mereMedscape Infectious Diseases, 3.07.2024
Tilføjet 3.07.2024
The RSV season is peaking earlier and entailing higher rates of hospitalization, according to Canadian data. Medscape Medical News
Læs mereMedscape Infectious Diseases, 28.06.2024
Tilføjet 28.06.2024
Moderna\'s mRNA vaccine mRESVIA has been recommended for a marketing authorization in the EU to protect against respiratory syncytial virus in older adults. Medscape Medical News
Læs mereMedscape Infectious Diseases, 28.06.2024
Tilføjet 28.06.2024
The U.S. CDC on Wednesday narrowed its recommendation for use of respiratory syncytial virus vaccines in older adults this year and held off on recommending their use for... Reuters Health Information
Læs mereMedscape Infectious Diseases, 4.06.2024
Tilføjet 4.06.2024
For the first time, an mRNA vaccine has been approved for an indication other than COVID-19. The vaccine will join a couple other immunizations currently on the market for respiratory syncytial virus. Medscape Medical News
Læs mereMorbidity and Mortality Weekly Report (MMWR), 31.05.2024
Tilføjet 31.05.2024
This report describes safety findings a year after the respiratory syncytial virus (RSV) vaccine was recommended for adults 60 and older.
Læs mereWei Cai, Sophie Köndgen, Kristin Tolksdorf, Ralf Dürrwald, Barbara Biere, Walter Haas, Thorsten Wolff, Silke Buda and Janine Reiche
Eurosurveillance latest updates, 17.05.2024
Tilføjet 17.05.2024
Medscape Infectious Diseases, 16.05.2024
Tilføjet 16.05.2024
Data raise questions about whether more testing for RSV and more vaccination are needed. Medscape Medical News
Læs mereECDC
ECDC COVID-19 updates, 4.05.2024
Tilføjet 4.05.2024
Influenza, SARS-CoV-2 and RSV activity in EU/EEA Member States continue to decrease or remain stable at low levels. Cases, including severe infections, can still occur and it therefore remains essential to continue testing patients presenting with severe acute respiratory symptoms in order to guide treatment and inform epidemiological assessments.
Læs mereECDC
ECDC COVID-19 updates, 26.04.2024
Tilføjet 26.04.2024
Influenza, SARS-CoV-2 and RSV activity in EU/EEA Member States continue to decrease or remain stable at low levels. Cases, including severe infections, can still occur and it therefore remains essential to continue testing patients presenting with severe acute respiratory symptoms in order to guide treatment and inform epidemiological assessments.
Læs mereMedscape Infectious Diseases, 19.04.2024
Tilføjet 19.04.2024
Last year saw more than 50 new drug approvals, many of which may help internists better manage several common conditions in their patients. Medscape Medical News
Læs mereECDC
ECDC COVID-19 updates, 15.04.2024
Tilføjet 15.04.2024
Influenza, SARS-CoV-2 and RSV activity in EU/EEA Member States continue to decrease or remain stable at low levels.
Læs mereECDC
ECDC COVID-19 updates, 12.04.2024
Tilføjet 12.04.2024
This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 7 - 13 April 2024 and includes updates on measles, avian influenza, COVID-19, Mpox, seasonal influenza, RSV, cholera and shigellosis.
Læs mereECDC
ECDC Communicable Disease Threats Report, 12.04.2024
Tilføjet 12.04.2024
This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 7 - 13 April 2024 and includes updates on measles, avian influenza, COVID-19, Mpox, seasonal influenza, RSV, cholera and shigellosis.
Læs mereSarah K Nørgaard, Jens Nielsen, Anne Christine Nordholm, Lukas Richter, Alena Chalupka, Natalia Bustos Sierra, Toon Braeye, Maria Athanasiadou, Theodore Lytras, Gleb Denissov, Oskari Luomala, Anne Fouillet, Isabelle Pontais, Matthias an der Heiden, Benedikt Zacher, Alina Weigel, Ivo Foppa, Kassiani Gkolfinopoulou, Ioannis Panagoulias, Anna Paldy, Tibor Malnasi, Lisa Domegan, Eva Kelly, Naama Rotem, Oksana Rakhlin, Francesca K de'Donato, Chiara Di Blasi, Patrick Hoffmann, Telma Velez, Kathleen England, Neville Calleja, Liselotte van Asten, Femke Jongenotter, Ana Paula Rodrigues, Susana Silva, Petra Klepac, Diana Gomez-Barroso, Inmaculada Leon Gomez, Ilias Galanis, Ahmed Farah, Rolf Weitkunat, Katarina Fehst, Nick Andrews, Tom Clare, Declan T Bradley, Mark G O'Doherty, Naoma William, Mark Hamilton, Bolette Søborg, Tyra G Krause, Nick Bundle and Lasse S Vestergaard
Eurosurveillance latest updates, 12.04.2024
Tilføjet 12.04.2024
Since the end of November 2023, the European Mortality Monitoring Network (EuroMOMO) has observed excess mortality in Europe. During weeks 48 2023–6 2024, preliminary results show a substantially increased rate of 95.3 (95% CI: 91.7–98.9) excess all-cause deaths per 100,000 person-years for all ages. This excess mortality is seen in adults aged 45 years and older, and coincides with widespread presence of COVID-19, influenza and respiratory syncytial virus (RSV) observed in many European countries during the 2023/24 winter season.
Læs mereMedscape Infectious Diseases, 10.04.2024
Tilføjet 10.04.2024
Pfizer said on Tuesday its respiratory syncytial virus (RSV) vaccine Abrysvo was well tolerated and generated an immune response in higher risk adults under the age of 60... Reuters Health Information
Læs mereECDC
ECDC COVID-19 updates, 8.04.2024
Tilføjet 8.04.2024
Influenza, SARS-CoV-2 and RSV activity in EU/EEA Member States continue to decrease or remain stable at low levels.
Læs mereWei Cai, Sophie Köndgen, Kristin Tolksdorf, Ralf Dürrwald, Ekkehard Schuler, Barbara Biere, Brunhilde Schweiger, Luise Goerlitz, Walter Haas, Thorsten Wolff, Silke Buda and Janine Reiche
Eurosurveillance latest updates, 29.03.2024
Tilføjet 29.03.2024
BackgroundNon-pharmaceutical interventions (NPIs) during the COVID-19 pandemic affected respiratory syncytial virus (RSV) circulation worldwide. AimTo describe, for children aged
Læs mereMedscape Infectious Diseases, 25.03.2024
Tilføjet 25.03.2024
Yale pulmonologist Denyse Lutchmansingh, MBBS, talks RSV vaccine recommendations and efficacy, prevention, risks, disease burden, and treatment. Medscape Infectious Diseases
Læs mereMedscape Infectious Diseases, 20.03.2024
Tilføjet 20.03.2024
Adult RSV infection can have serious consequences. These five things to know will help you recognize and protect the adult populations most vulnerable to severe disease. Medscape Infectious Diseases
Læs mereECDC
ECDC COVID-19 updates, 20.03.2024
Tilføjet 20.03.2024
This Reporting Protocol describes data collection for influenza, COVID-19, and other respiratory viruses (such as RSV or new viruses of public health concern) in the EU/EEA and wider WHO European Region. Data collection is integrated for most datasets in line with the operational considerations for respiratory virus surveillance in Europe.
Læs mereMedscape Infectious Diseases, 14.03.2024
Tilføjet 14.03.2024
With a maternal vaccine already on the market to protect newborns from RSV, the outlook for another looked promising, but latest phase 3 trial of a new candidate is now halted over safety concerns. Medscape Medical News
Læs mereMedscape Infectious Diseases, 14.03.2024
Tilføjet 14.03.2024
Almost 10,000 older adults die each year due to respiratory syncytial virus. Two new FDA-approved RSV vaccines may help lower that number, and also ease congestion in hospitals. Medscape
Læs mereMedscape Infectious Diseases, 8.03.2024
Tilføjet 8.03.2024
Medscape Infectious Diseases, 2.03.2024
Tilføjet 2.03.2024
Pfizer on Thursday said a single dose of its new respiratory syncytial virus (RSV) vaccine Abrysvo maintained its ability to protect against the illness through a second... Reuters Health Information
Læs mereMónica López-Lacort, Cintia Muñoz-Quiles, Ainara Mira-Iglesias, F Xavier López-Labrador, Beatriz Mengual-Chuliá, Carlos Fernández-García, Mario Carballido-Fernández, Ana Pineda-Caplliure, Juan Mollar-Maseres, Maruan Shalabi Benavent, Francisco Sanz-Herrero, Matilde Zornoza-Moreno, Jaime Jesús Pérez-Martín, Santiago Alfayate-Miguelez, Rocío Pérez Crespo, Encarnación Bastida Sánchez, Ana Isabel Menasalvas-Ruiz, Mª Cinta Téllez-González, Samuel Esquiva Soto, Carlos Del Toro Saravia, Iván Sanz-Muñoz, José María Eiros, Vanesa Matías Del Pozo, Marina Toquero-Asensi, Eliseo Pastor-Villalba, José Antonio Lluch-Rodrigo, Javier Díez-Domingo and Alejandro Orrico-Sánchez
Eurosurveillance latest updates, 9.02.2024
Tilføjet 9.02.2024
The monoclonal antibody nirsevimab was at least 70% effective in preventing hospitalisations in infants with lower respiratory tract infections (LRTI) positive for respiratory syncytial virus (RSV) in Spain (Oct 2023–Jan 2024), where a universal immunisation programme began late September (coverage range: 79–99%). High protection was confirmed by two methodological designs (screening and test-negative) in a multicentre active surveillance in nine hospitals in three regions. No protection against RSV-negative LRTI-hospitalisations was shown. These interim results could guide public-health decision-making.
Læs mereLisa Staadegaard, Michel Dückers, Jojanneke van Summeren, Rob van Gameren, Clarisse Demont, Mathieu Bangert, You Li, Jean-Sebastien Casalegno, Saverio Caini and John Paget
Eurosurveillance latest updates, 2.02.2024
Tilføjet 2.02.2024
BackgroundThere is currently no standardised approach to estimate respiratory syncytial virus (RSV) epidemics’ timing (or seasonality), a critical information for their effective prevention and control. AimWe aimed to provide an overview of methods to define RSV seasonality and identify factors supporting method choice or interpretation/comparison of seasonal estimates. MethodsWe systematically searched PubMed and Embase (2016–2021) for studies using quantitative approaches to determine the start and end of RSV epidemics. Studies’ features (data-collection purpose, location, regional/(sub)national scope), methods, and assessment characteristics (case definitions, sampled population’s age, in/outpatient status, setting, diagnostics) were extracted. Methods were categorised by their need of a denominator (i.e. numbers of specimens tested) and their retrospective vs real-time application. Factors worth considering when choosing methods and assessing seasonal estimates were sought by analysing studies. ResultsWe included 32 articles presenting 49 seasonality estimates (18 thereof through the 10% positivity threshold method). Methods were classified into eight categories, two requiring a denominator (1 retrospective; 1 real-time) and six not (3 retrospective; 3 real-time). A wide range of assessment characteristics was observed. Several studies showed that seasonality estimates varied when methods differed, or data with dissimilar assessment characteristics were employed. Five factors (comprising study purpose, application time, assessment characteristics, healthcare system and policies, and context) were identified that could support method choice and result interpretation. ConclusionMethods and assessment characteristics used to define RSV seasonality are heterogeneous. Our categorisation of methods and proposed framework of factors may assist in choosing RSV seasonality methods and interpretating results.
Læs mereMedscape Infectious Diseases, 1.02.2024
Tilføjet 1.02.2024
Amid the current winter wave surge of respiratory virus cases, how challenging is it for physician\'s to distinguish between, diagnose, and treat COVID-19 vs RSV and influenza? Medscape Medical News
Læs mereCorinna Ernst, Dritan Bejko, Leo Gaasch, Emilie Hannelas, Isaline Kahn, Charlotte Pierron, Nesrine Del Lero, Claude Schalbar, Elsa Do Carmo, Michel Kohnen, Emmanuelle Andlauer, Pauline Hublart, Silvana Masi, Isabel de la Fuente Garcia, Anne Vergison and Joël Mossong
Eurosurveillance latest updates, 26.01.2024
Tilføjet 26.01.2024
After Luxembourg introduced nirsevimab immunisation against respiratory syncytial virus (RSV), estimated neonatal coverage was 84% (1,277 doses/1,524 births) in 2023. That year, paediatric RSV-related hospitalisations, especially concerning infants
Læs mereECDC
ECDC COVID-19 updates, 13.12.2023
Tilføjet 13.12.2023
This Reporting Protocol describes data collection for influenza, COVID-19, and other respiratory viruses (such as RSV or new viruses of public health concern) in the EU/EEA and wider WHO European Region. Data collection is integrated for most datasets in line with the operational considerations for respiratory virus surveillance in Europe.
Læs mereMaría Iglesias-Caballero, Sara Camarero-Serrano, Sarai Varona, Vicente Mas, Cristina Calvo, María Luz García, Juan García-Costa, Sonia Vázquez-Morón, Sara Monzón, Albert Campoy, Isabel Cuesta, Francisco Pozo and Inmaculada Casas
Eurosurveillance latest updates, 8.12.2023
Tilføjet 8.12.2023
To advance our understanding of respiratory syncytial virus (RSV) impact through genomic surveillance, we describe two PCR-based sequencing systems, (i) RSVAB-WGS for generic whole-genome sequencing and (ii) RSVAB-GF, which targets major viral antigens, G and F, and is used as a complement for challenging cases with low viral load. These methods monitor RSV genetic diversity to inform molecular epidemiology, vaccine effectiveness and treatment strategies, contributing also to the standardisation of surveillance in a new era of vaccines.
Læs mereMedscape Infectious Diseases, 6.12.2023
Tilføjet 6.12.2023
COVID-19 appears to be heading for a holiday season increase across most of the United States. WebMD Health News
Læs mereECDC
ECDC COVID-19 updates, 28.11.2023
Tilføjet 28.11.2023
This Reporting Protocol describes data collection for influenza, COVID-19, and other respiratory viruses (such as RSV or new viruses of public health concern) in the EU/EEA and wider WHO European Region. Data collection is integrated for most datasets in line with the operational considerations for respiratory virus surveillance in Europe.
Læs mereMedscape Infectious Diseases, 12.11.2023
Tilføjet 12.11.2023
Despite our prevention efforts, some unlucky few may contract not just one of these viruses, but two at once or in close succession during the winter season. WebMD Health News
Læs mere